Effectiveness of different disinfectants and combinations against SARS-CoV-2 nucleic acid in COVID-19 quarantine wards

Zhang, Ying; Zhou, Jianguo; Zhu, Haitao; Lu, Chunmei; Ye, Lan; Chunyu, Lingfeng; Li, Guoping; Fu, Pan; Zhou, Wenhao

doi:10.21203/rs.3.rs-2531629/v1

Cited by 2 publications

(1 citation statement)

References 32 publications

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“…The representative cruise ship with the theme of corporate brand culture is Disney fantasy. The magnificent atrium space of Disney fantasy is located in the middle of a three-story ship [2]. The plane is square and adopts a vertical enclosure, which is the design style of the new art school.…”

Section: Theme Type Of Interior Decoration In Cruise Atriummentioning

confidence: 99%

Theme design and style features of interior decoration of cruise atrium

2023

jceup

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when analyzing the theme design and style characteristics of the interior decoration of the cruise ship atrium, it is mainly to analyze the space of the cruise ship atrium, pay attention to its theme design and scene, analyze the space form, decorative style and functional layout of the interior decoration of the cruise ship atrium, elaborate the theme design and style characteristics in combination with the research on the theme design of the interior decoration of the cruise ship atrium, and effectively obtain the optimization suggestions for the interior decoration of the cruise ship atrium. Interior decoration theme of cruise atriumThe cruise atrium refers to the courtyard space connecting the main corridor, stairs, elevators and other spaces inside the cruise, which usually includes a large lobby with functions such as lobby, rest, reception, reception, registration, business and so on. Its functions mainly include satisfying passengers' boarding, handling relevant formalities and consulting services, providing a space for the cruise interior space to share the external environment, and providing tourists with a sense of direction. The atrium is usually located in the middle of the ship, with a height of about 2-3 floors. Although the atrium area accounts for 4%~8% of the total cruise public area, the passenger flow at the atrium accounts for about 60%~75% of the total passenger flow. Therefore, the design of the atrium is very important for the cruise ship experience. The design of cruise atrium should not only comprehensively consider the number of passengers getting on and off the ship, personnel flow, SOLAS and classification society related safety and fire protection regulations and supporting commercial service functions, but also the theme design of the atrium. The cruise theme design centers on a clear concept to plan the interior design, build a series of mutually coordinated space and element structure relationships, and build a cruise cultural atmosphere and business system with all-round differences around this theme [1] . That is to integrate the space atmosphere, style tendency, space arrangement, activity organization and operation strategy into its internal space, so as to create a different cruise leisure tourism experience. At present, there is still insufficient research on the theme design of the interior decoration of the cruise atrium at home and abroad, which needs further research and summary. Style representation of interior decoration theme of cruise atriumThe cruise theme first appeared in the atrium in 1908, namely the RMS Olympic of the white

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Section: Theme Type Of Interior Decoration In Cruise Atriummentioning

confidence: 99%

Theme design and style features of interior decoration of cruise atrium

2023

jceup

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Determining the efficacy of disinfectants at nucleic acid degradation

Wilkinson,

Meldrum,

Maggs

et al. 2023

Journal of Applied Microbiology

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Aims Nucleic acids, particularly antibiotic resistance genes, are commonly found on surfaces within healthcare environments, with levels not reducing following cleaning. Within the UK, there are no regulations for testing disinfectants against nucleic acids. Methods and Results A series of commonplace in vitro methods were used to determine disinfectant-induced physical and functional damage to various nucleic acids; RNA (10 μg), genomic DNA (2 μg), and plasmids (1 μg). Using these methods, the optimal residence time (10 minutes) and working concentration (10%) were determined for a new disinfectant. Furthermore, comparison of disinfectants with different active ingredients including lactic acid (LA), sodium hydroxide (NaOH), chloroxylenol (PCMX) and quaternary ammonium compounds (QAC) were compared to controls. All disinfectants showed greater degradation by gel electrophoresis of genomic DNA and RNA than of purified plasmids. Functional analysis using qPCR and PCR demonstrated that no disinfectant tested (apart from control) could damage DNA to the level where PCR amplification was not possible, and only the NaOH reagent could achieve this for RNA. Conclusions The set of methods described herein provides a platform for future standardisation and potential regulation regarding monitoring cleaning solutions for their activity against nucleic acids.

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Effectiveness of different disinfectants and combinations against SARS-CoV-2 nucleic acid in COVID-19 quarantine wards

Cited by 2 publications

References 32 publications

Theme design and style features of interior decoration of cruise atrium

Theme design and style features of interior decoration of cruise atrium

Determining the efficacy of disinfectants at nucleic acid degradation

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