Effectiveness of different modalities of cognitive remediation on symptomatological, neuropsychological, and functional outcome domains in schizophrenia: A prospective study in a real-world setting

Improving Social Cognition in Schizophrenia: A Pilot Intervention Combining Computerized Social Cognition Training With Cognitive Remediation

“…COGPACK is a computerized, commercially available CR program developed for persons with severe mental illness, with demonstrated efficacy in schizophrenia. 26,28,29 The curriculum of COGPACK exercises used in the current study is similar to that used in past controlled trials. 22,26,30 The curriculum consists of a standardized set of computerized exercises that provides practice of the broad range of cognitive functions and overlaps with cognitive domains assessed by the MCCB-MATRICS.…”

Cognitive Remediation for Schizophrenia: A Review of Recent Findings

“…Several studies support the implementation of CR in real-world clinical settings [17,20,21,44], although there remains uncertainty about the specific parameters of implementation (e.g., duration, approach, dosage, etc.). As stated above, computerized programs can ease the burden of dissemination in that they require less staff training, and enhance standardization of procedures.…”

“…Regarding generalization to functional outcomes, the recent research also indicates that gains tend to generalize to real-world skills. Ten of the sixteen studies found supportive evidence of generalizability to functional outcomes [12][13][14][15][16][17][18][19][20][21]. One study [22] reported no improvement in functional outcome and another study [12] found that functional outcomes improved when skills-training followed CR, but not after CR alone.…”

“…The recent research does not resolve this issue, as gains are apparent in studies with and without adjunctive treatments. Only four of the recent 16 studies reported systematic integration of higher-level approaches with structured approaches for psychosocial treatment [12,17,20,21]. These studies all yielded positive results for functional outcomes, including work outcomes and social skills.…”

Investigaciones en rehabilitación cognitiva para pacientes con esquizofrenia (2004-2013): una revisión temática en beneficio de propuestas para etapas iniciales del trastorno

“…En un análisis posterior de las investigaciones señaladas 23,24 , los autores reportaron que el tratamiento muestra mayor eficacia si el paciente cumple con las siguientes condiciones: menor uso de antipsicóticos, menor severidad de síntomas y mejor funcionamiento neurocognitivo de base (especialmente ejecutivo y memoria); además, la menor edad al momento de la intervención, como uno de los mejores predictores de mejoría a nivel de desempeño funcional 25 .…”