Soil and climatic conditions of the region allow to obtain annually high stable yields of sugar beet. The increase in yield is directly related to a complex of factors, including high-yielding varieties and hybrids, a complex of fertilizers and chemical means of crop protection. In agricultural enterprises of the region, subject to the technology of sugar beet cultivation, the yield of root crops receives up to 50 t / ha and above. Bayer CropScience has created a new systemic herbicide Conviso 1, MD (ALS inhibitor) for sugar beet specifically for SMART hybrids that are part of the CONVISO SMART technology. The article presents the results of two-year studies to study the effectiveness of the herbicide Conviso 1, MD. The tests were carried out on the experimental fields of the ISA-branch of the FGBNU FNATS VIM. The task of the research was to determine the effectiveness of the herbicide Conviso 1, MD with a single, double and triple application on sugar beet crops SMART hybrid Calledonia KVS, in order to establish its effect on the weediness of crops and crop yield. Tests of the herbicide were carried out in 2020 and 2021 in fourfold repetition. The size of the experimental plots is 50 m2. The soil of the experimental site is dark gray forest heavy loamy, the humus content is 3.8%, the pH is 5.8 - 6.0, the predecessor is winter wheat. Spraying of sugar beet crops was carried out in phase 1-3, 3-4 and 6-8 leaves of the culture with threefold application, 3-4 and 6-8 real leaves of the culture - with double, and in phase 3-4 pairs of real sugar beet leaves with a single one. Field tests to study the effectiveness of the herbicide Conviso 1, MD were carried out according to the scheme of experience: Conviso 1, MD - 0.5 + 0.5 + 0.5 l / ha; Conviso 1, MD – 0,75 + 0,75 l/ha; Conviso 1, MD – 1.5 l/ha; control – without herbicides. As a result of research, it was found that the weediness of crop crops with annual dicotyledonous and cereal weeds decreased by 86-99%. As a result, the yield of root crops increased by 32.5-78.3%.