[Purpose] The aim of present study was to investigate the effects of isometric
quadriceps exercise on muscle strength, pain, and function in knee osteoarthritis.
[Subjects and Methods] Outpatients (N=42, 21 per group; age range 40–65
years; 13 men and 29 women) with osteoarthritis of the knee participated in the study. The
experimental group performed isometric exercises including isometric quadriceps, straight
leg raising, and isometric hip adduction exercise 5 days a week for 5 weeks, whereas the
control group did not performed any exercise program. The outcome measures or dependent
variables selected for this study were pain intensity, isometric quadriceps strength, and
knee function. These variables were measured using the Numerical Rating Scale (NRS),
strength gauge device, and reduced WOMAC index, respectively. All the measurements were
taken at baseline (week 0) and at the end of the trial at week 5. [Results] In
between-group comparisons, the maximum isometric quadriceps strength, reduction in pain
intensity, and improvement in function in the isometric exercise group at the end of the
5th week were significantly greater than those of the control group (p<0.05).
[Conclusion] The 5-week isometric quadriceps exercise program showed beneficial effects on
quadriceps muscle strength, pain, and functional disability in patients with
osteoarthritis of the knee.