Effectiveness of erythropoietin in correcting anemia in patients of chronic kidney disease.

Shakir, Waqas; Khurshid, Asim; Talib, Muhammad Abu

doi:10.29309/tpmj/2020.27.04.3683

Cited by 1 publication

(3 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A study conducted by Shuaib et al 17 has also reported 24.97±15.88 kilograms mean weight of the children undergoing hemodialysis. Shakir et al 18 has also reported 19.65± 4.71 kilograms mean weight, similar to our results. Jaramillo et al 19 from Mexico has also reported similar results.…”

Section: Discussionsupporting

confidence: 93%

“…A study conducted by Shuaib et al 17 has also reported 11.91±7.06 months mean duration on hemodialysis, close to our study results. Shakir et al 18 has also reported similar results. Jaramillo et al 19 from Mexico has also reported similar results.…”

Section: Discussionmentioning

confidence: 54%

“…A study conducted by Shuaib et al 17 has also reported 66.7% boys with CKD, similar to our findings. Shakir et al 18 has also reported 60.8% male gender predominance. Jaramillo et al 19 from Mexico has also reported similar results.…”

Section: Discussionmentioning

confidence: 89%

See 2 more Smart Citations

Correlation of Iron Profile with Different Stages of Chronic Kidney Disease in Children Presenting at a Tertiary Care Hospital

Ishaq¹,

Imran²,

Raza³

et al. 2021

PJMHS

View full text Add to dashboard Cite

Aim: To determine correlation of iron profile in children with different stages of chronic kidney disease (CKD) presenting to tertiary care hospital. Methodology: A total of 81 children with chronic kidney disease stage having glomerular filtration rate (GFR) less than 90 (ml/min/m2) aged 1 – 14 years of either sex were included. Three ml serum sample was taken in vial by hospital duty doctor for serum ferritin level, serum iron, transferrin saturation and total iron binding capacity. The sample was sent to hospital laboratory for reporting. Iron profiling was done evaluating hemoglobin (g/dl), serum iron (ug/dl), serum ferritin (ng/ml), transferrin saturation (%) and total iron binding capacity (ug/dl) while iron load was defined as serum ferritin levels above 300 ng/ml. Correlation of iron profile with different stages of CKD was determined applying one-way analysis of variance (ANOVA). Results: In a total 81 children, 46 (56.8%) were boys while overall mean age was 7.79±2.30 years. Mean duration on hemodialysis was 11.52 ± 9.97 months. Iron overload was observed in 26 (32.1%) children. Significant association of age above 7 years (p=0.031) and residential status as rural (p=0.017) was noted with iron overload whereas iron overload was increasing with increase in stages of CKD (p=0.002). Hemoglobin levels decreased significantly with increase in stages of CKD (p<0.001). Serum iron levels increased significantly with increase in the CKD stages (p=0.039). Serum ferritin levels were increasing significantly with the increase in CKD stages (p=0.031). Transferrin saturation also increased significant with increase in CKD stages (p=0.027). Conclusion: High frequency of iron overload was noted in children with CKD on maintenance hemodialysis and there was linear relationship with stages of CKD and iron overload. Significant correlation of hemoglobin, serum iron, serum ferritin and transferrin saturation was observed with different stages of CKD. Keywords: Iron overload, maintenance hemodialysis, ferritin level.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 54%