Effectiveness of Geniculate Artery Embolization for Chronic Pain after Total Knee Replacement—A Pilot Study

Chau, Yves; Roux, Christian; Gonzalez, Jean-François; Breuil, Véronique; Dompsure, Régis Bernard de; Fontas, Éric; Rudel, Alexandre; Sédat, Jacques

doi:10.1016/j.jvir.2023.06.026

Cited by 6 publications

(5 citation statements)

References 33 publications

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“…GAE is also hypothesised to assist in managing persistent knee pain despite arthroplasty. Up to 20% of patients who undergo knee arthroplasty claim to continue to experience pain, of which 10–15% is unexplained [ 18 ]. Chau et al explored the effectiveness of GAE for those experiencing chronic pain post TKR.…”

Section: Discussionmentioning

confidence: 99%

“…This was a single-centre, single-arm study including 12 patients, with a mean interval of 2.8 years following TKR, all experiencing pain since surgery. Those with potential alternative underlying causes of pain were excluded [ 18 ]. All patients were found to have abnormal synovial hypervascularity.…”

Section: Discussionmentioning

confidence: 99%

“…All patients were found to have abnormal synovial hypervascularity. The mean number of arteries embolised following TKR compared with management of knee OA was lower [ 18 ]. The majority (58%) had clinical improvement in KOOS scores at 3 to 6 month follow up.…”

Section: Discussionmentioning

confidence: 99%

“…VAS scores at rest and walking decreased by 72% and 41%, respectively. In contrast, 30% had a transient increase in pain for two weeks following embolization [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

“…These are still preliminary data regarding managing unexplained chronic pain post TKR so should be viewed with caution. There were a few patients for which the pain increased, although, overall, the outcomes showed improved results for up to 12 months [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

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Selective Genicular Artery Embolization in the Management of Osteoarthritic Knee Pain—A Narrative Review

O’Brien,

Blakeney,

Soares

2024

JCM

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Many people with pain from osteoarthritis (OA) of the knee are either not ready for surgery or may never be surgical candidates. Genicular artery embolization (GAE) is a new proposed management for those with pain despite maximum medical management. It has historically been used to manage recurrent spontaneous haemarthrosis following total knee replacement, but newer studies are showing a positive effect in managing pre-arthroplasty knee OA. The goal of this review is to summarise current and relevant literature from searches of computerised databases and relevant journals, and analyse their results. Studies included show that GAE has promising outcomes in managing mild to moderate OA knee pain in those who have exhausted at least 3 months of conservative therapy. Most studies show improvements in VAS pain and PROM scores (including KOOS, and/or WOMAC). Minimal adverse effects have been associated in up to two years of follow up, the majority of which are self-resolving. The article précises a concise general procedural technique for performing GAE, as well as comparing and contrasting different embolic agents that may be utilised. GAE shows promising outcomes in management of mild to moderate OA knee pain. In the future, there will need to be higher volume studies to determine effectiveness, suitable candidates, and other potential adverse effects.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…VAS scores at rest and walking decreased by 72% and 41%, respectively. In contrast, 30% had a transient increase in pain for two weeks following embolization [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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