Effectiveness of glass ionomer cements in the restorative treatment of radiation-related caries — a systematic review

Impact of Irradiation on the Adhesive Performance of Resin-Based Dental Biomaterials: A Systematic Review of Laboratory Studies

“…The review was confined to laboratory studies that evaluated resin-based biomaterials, which limits the scope of its findings. Glass ionomer cements can release fluoride and act as refillable fluoride reservoir, potentially curbing the development of secondary caries, especially in high-risk patients undergoing radiation therapy [ 10 ]. However, it remains unclear which biomaterial is most suitable for treating radiation-related caries based on available clinical evidence [ 10 ].…”

“…Radiation-related caries occur in approximately 29% of patients within 3 months of completing treatment [ 9 , 10 ]. This susceptibility to caries is largely due to changes in saliva quantity and quality, as well as direct radiation effects on enamel and dentin [ 11 , 12 , 13 , 14 ].…”

“…This susceptibility to caries is largely due to changes in saliva quantity and quality, as well as direct radiation effects on enamel and dentin [ 11 , 12 , 13 , 14 ]. In addition, oral trismus and mucositis, common side-effects of radiation therapy, can lead to inadequate biofilm control and increased consumption of carbohydrate-rich foods, both contributing factors to radiation-related caries [ 8 , 10 , 15 ].…”

“…Patients with head and neck cancer who undergo radiation therapy require comprehensive dental care, with special measures needed for caries prevention and control [ 11 , 15 , 16 , 17 ]. Owing to the high incidence of radiation-related caries, restorative interventions are often necessary [ 10 ]. In recent years, there has been an increase in studies evaluating the impact of irradiation on enamel, dentin, and the adhesive performance dental biomaterials [ 12 , 18 ].…”

Incorporation of Nanomaterials in Glass Ionomer Cements—Recent Developments and Future Perspectives: A Narrative Review

“…With commercial variants available since 1972 [ 12 ], GICs have several advantages over other types of materials, including a strong chemical bond with hard dental tissues and clinical metals [ 13 ], good adhesion properties in moist environments [ 14 ], a prolonged release of fluoride, positive effects on tooth health [ 15 ], and lower cytotoxicity when compared with other types of dental restoration materials [ 16 ]. Several review articles present GICs and their advantages in practical application as dental restoration materials [ 11 , 17 , 18 , 19 , 20 ]. At the same time, their hydrophilicity allows them to bond to the teeth in the presence of residual fluids [ 21 ].…”