Effectiveness of hand-cleansing formulations containing tea tree oil assessed ex vivo on human skin and in vivo with volunteers using European standard EN 1499

Messager, S.; Hammer, Katherine A.; Carson, Christine; Riley, Thomas V.

doi:10.1016/j.jhin.2004.06.032

Cited by 35 publications

(31 citation statements)

References 34 publications

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“…Moreover, the antimicrobial activity of oils is dose-dependent with greater activity seen at the higher oil concentrations. The study concerning the antimicrobial effect of tea tree oil showed that hygienic skin wash with 5 % tea tree oil was significantly more active against E. coli K12 growth than a nonmedicated soft soap [20]. Manou et al [17] found that 3 % Thymus vulgaris essential oil inhibited the growth of S. aureus, P. aeruginosa and E. coli in formulations O/W and W/O, C. albicans only in formulations W/O, but not against the A. niger.…”

Section: Discussionmentioning

confidence: 99%

Essential Oils and Herbal Extracts as Antimicrobial Agents in Cosmetic Emulsion

et al. 2012

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The cosmetic industry adapts to the needs of consumers seeking to limit the use of preservatives and develop of preservative-free or self-preserving cosmetics, where preservatives are replaced by raw materials of plant origin. The aim of study was a comparison of the antimicrobial activity of extracts (Matricaria chamomilla, Aloe vera, Calendula officinalis) and essential oils (Lavandulla officinallis, Melaleuca alternifolia, Cinnamomum zeylanicum) with methylparaben. Extracts (2.5 %), essential oils (2.5 %) and methylparaben (0.4 %) were tested against Pseudomonas aeruginosa ATCC 27853, Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 29213, Candida albicans ATCC 14053. Essentials oils showed higher inhibitory activity against tested microorganism strain than extracts and methylparaben. Depending on tested microorganism strain, all tested extracts and essential oils show antimicrobial activity 0.8-1.7 and 1-3.5 times stronger than methylparaben, respectively. This shows that tested extracts and essential oils could replace use of methylparaben, at the same time giving a guarantee of microbiological purity of the cosmetic under its use and storage.

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Section: Discussionmentioning

confidence: 99%

Essential Oils and Herbal Extracts as Antimicrobial Agents in Cosmetic Emulsion

et al. 2012

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“…However, activity has also been demonstrated using time-kill assays (34,48,80,106), suspension tests (107), and "ex vivo"-excised human skin (108 Mechanism of antibacterial action. The mechanism of action of TTO against bacteria has now been partly elucidated.…”

Section: Antibacterial Activitymentioning

confidence: 99%

“…The benefits of using TTO in a handwash formulation include its antiseptic effects and increased handwashing compliance. A recent handwash study using volunteers showed that either a product containing 5% TTO and 10% alcohol or a solution of 5% TTO in water performed significantly better than soft soap, whereas a handwash product containing 5% TTO did not (108).…”

Section: Clinical Efficacymentioning

confidence: 99%

Melaleuca alternifolia(Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties

2006

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SUMMARY Complementary and alternative medicines such as tea tree (melaleuca) oil have become increasingly popular in recent decades. This essential oil has been used for almost 100 years in Australia but is now available worldwide both as neat oil and as an active component in an array of products. The primary uses of tea tree oil have historically capitalized on the antiseptic and anti-inflammatory actions of the oil. This review summarizes recent developments in our understanding of the antimicrobial and anti-inflammatory activities of the oil and its components, as well as clinical efficacy. Specific mechanisms of antimicrobial and anti-inflammatory action are reviewed, and the toxicity of the oil is briefly discussed.

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“…Essential oils such as tea tree and eucalyptus oil have gained acceptance as safe and effective antiseptics (Warnke et al, 2005;Cox et al, 2000). There is a search for plants with more potent PSM for applications in the feed and food industry and for medical applications (Greathead, 2003;Burt, 2004;Messager et al, 2005;de Sousa et al, 2004;Allahverdiyev et al, 2004). Lantana camara Linn.…”

Section: Introductionmentioning

confidence: 99%