Effectiveness of hyaluronic acid in post-surgical cures following partial matricectomies with the phenol/alcohol technique: A randomized clinical trial

Lopezosa-Reca, Eva; Nova, Alfonso Martínez; Sánchez-Rodríguez, Raquel; Gijón-Noguerón, Gabriel; Marchena‐Rodriguez, Ana; Martínez-Rico, Magdalena; Alabau-Dasi, Raquel

doi:10.1016/j.jtv.2023.01.010

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…The administration of PV-I is more effective than topical honey for post-operative wound care in reducing bleeding; 29 however, there was no significant difference between the administration of PV-I and hypochlorous acid cream as a pre-operative surface disinfectant. 23 There was no significant difference in the administration of PV-I in reducing fever compared to CHX, 19 pain compared to hyaluronic acid cream, 16 skin abscess, 25 and readmission compared to CHX. 19 However, silver foam dressing was significantly more effective than PV-I in reducing hospital stay in patients with pemphigus vulgaris.…”

Section: Resultsmentioning

confidence: 96%

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Uncovering the Benefits of Povidone Iodine Compared to Other Therapeutic Agents in Wound Infection Prevention and Healing Outcomes: A Scoping Review

Harun,

Haroen,

Mirwanti

et al. 2024

JMDH

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Background The selection of an appropriate chemical solution in wound care reduces the severity of wounds and accelerates the healing process. Povidone-iodine (PV-I), a chemical solution popularly known as an antiseptic, is frequently used in studies of wound care to prevent wound infection and accelerate woud the process of wound healing. Objective To identify the latest evidence on the benefits of PV-I in wound infection prevention and healing in all areas. Methods This review is a scoping review by Arskey and O’Malley and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) is used for reporting. The literature search used databases including PubMed, CINAHL, and search engines such as Scopus. This study was conducted using thematic analysis. Results This review yielded 19 out of 2109 studies that were identified in the initial search. Four outcomes comprised 20 sub-outcomes have been identified. Although strong evidence is lacking, PV-I in the form of foam is effective in improving wound healing, shortening healing time, and producing fewer adverse events than hydrocelluers. Moreover, saline and PV-I are effective as skin disinfectants when compared to saline alone in reducing surgical site infection (SSI), and they are also more effective than hypochlorous acid in improving wound healing. Nevertheless, there was no difference between PV-I and hypochlorous acid in the prevention of SSI and bacterial growth. In terms of healing time, silver foam and hyaluronic acid were more favorable than PV-I. Moreover, the use of chlorhexidine to improve SSI and silver dressing to improve hospital stay is more favorable than that of PV-I. Conclusion There is limited evidence regarding the effectiveness of wound care outcomes, and the efficacy of PV-I as a surface disinfectant for wound infection prevention remains controversial. Consequently, PV-I is not highly recommended for wound care, and further investigation into the effectiveness of PV-I as a surface disinfectant is required for various types of surgeries.

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Section: Resultsmentioning

confidence: 96%

“… 32 Moreover, ingrown toenail post-operative wounds required a longer time to heal in the PV-I group than in the hyaluronic acid group. 16 PV-I is not only used for operative wounds but may also be used for care in chronic wounds.…”

Section: Discussionmentioning

confidence: 99%

Uncovering the Benefits of Povidone Iodine Compared to Other Therapeutic Agents in Wound Infection Prevention and Healing Outcomes: A Scoping Review

Harun,

Haroen,

Mirwanti

et al. 2024

JMDH

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Update on Low-Molecular Weight Hyaluronic Acid in Dermatology: A Scoping Review

Waggett,

Lyles,

Schlesinger

2024

EMJ Dermatol

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Introduction: Hyaluronan, or hyaluronic acid (HA), is a naturally occurring glycosaminoglycan present in the skin, joints, and eyes that provides hydration, lubrication, protection, and other important benefits. HA in dermatology is commonly discussed in the context of its anti-ageing properties. However, both pre-clinical and clinical studies have shown numerous applications of HA, low-molecular-weight (LMW) HA, and hybrid LMW/high-molecular-weight HA in dermatology. LMW-HA exhibits antioxidant, anti-tumour, and angiogenic properties, and given its size, an ability to fully penetrate the skin. Aims: The purpose of this review was to explore the current science and utility of LMW-HA in clinical dermatology and provide an update on its use. Methods: A PubMed search from 2003–2023 on LMW-HA was conducted to evaluate LMW-HA’s utility in clinical dermatology. Results: Identified applications of LMW-HA in medical dermatology included treatment of acute and chronic wounds, rosacea, scars, and seborrhoeic dermatitis. Cosmetic applications of LMW and hybrid HA included treatment of skin ageing, enlarged pores, and skin laxity, as well as enhancement of skin hydration. Topical LMW-HA administration promoted healing after cosmetic procedures, chemical peels, and ingrown toenail surgery. Studies of topical and oral LMW-HA demonstrated adequate safety, and newer techniques of administration, such as needleless jet injection, are available. Conclusion: Exploration and understanding of the properties and benefits of LMW-HA are key to translating its usage in the clinical setting. Basic scientists and dermatologists have achieved substantial progress over the past two decades, and several applications of LMW-HA in dermatology were identified. Additional advantages of LMW-HA are worth exploring.

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Hyaluronic Acid in Nanopharmaceuticals: An Overview

Matalqah,

Lafi,

Asha

2024

CIMB

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Hyaluronic acid (HA) is a naturally occurring, long, unbranched polysaccharide that plays a critical role in maintaining skin structure and hydration. Its unique properties make it a valuable component in the field of nanopharmaceuticals. The combination of HA into nanopharmaceuticals enhances its ability to interact with various therapeutic agents, improving the delivery and efficacy of drugs. HA-based nanoparticles, including solid lipid nanoparticles, and polymeric nanogels, offer controlled release, enhanced stability, and targeted delivery of therapeutic agents. These innovations significantly improve therapeutic outcomes and reduce side effects, making HA an essential tool in modern medicine. In general, HA-modified liposomes enhance drug encapsulation and targeting, while HA-modified solid lipid nanoparticles (SLNs) provide a solid lipid core for drug encapsulation, offering controlled release and stability. This article provides an overview of the potential applications and recent advancements of HA in nanopharmaceuticals, emphasizing its significant impact on the evolving field of targeted drug delivery and advanced therapeutic strategies. By delving into the unique properties of HA and its compatibility with various therapeutic agents, this review underscores the promising potential of HA in revolutionizing nanopharmaceuticals.

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Effectiveness of hyaluronic acid in post-surgical cures following partial matricectomies with the phenol/alcohol technique: A randomized clinical trial

Cited by 3 publications

References 19 publications

Uncovering the Benefits of Povidone Iodine Compared to Other Therapeutic Agents in Wound Infection Prevention and Healing Outcomes: A Scoping Review

Uncovering the Benefits of Povidone Iodine Compared to Other Therapeutic Agents in Wound Infection Prevention and Healing Outcomes: A Scoping Review

Update on Low-Molecular Weight Hyaluronic Acid in Dermatology: A Scoping Review

Hyaluronic Acid in Nanopharmaceuticals: An Overview

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