Effectiveness of intradialytic exercise on dialysis adequacy, physiological parameters, biochemical markers and quality of Life – A pilot study

Abstract

End-stage renal disease is emerging as a major public health problem in the developing countries. It must be treated with renal replacement therapy and hemodialysis (HD) is the most widely used therapy and the only maintenance treatment if kidney transplant is not feasible. This study aimed to determine the effectiveness of intradialytic exercise on dialysis efficacy, physiological parameters, biochemical markers, and quality of life among patients on HD. Experimental research design was adopted to conduct the study with 20 patients in our HD unit who met the inclusion criteria and patients were randomly allocated into experimental group and control group. The experimental group received intradialytic exercise during the first 2 h of HD besides receiving routine care compared to the control group. Data were tabulated and analyzed using the SPSS package. The finding of the present pilot study reveals that the prescribed intradialytic exercise intervention resulted in significant improvement in Kt/V, serum creatinine, blood urea, serum potassium, phosphorous, and quality of life. Based on the findings of the present study, it can be concluded that intradialytic exercise program is a safe complementary intervention and does not need an extra time of the patient and showed improvement in patients' outcome.

The role of exercise in improving patient‐reported outcomes in individuals on dialysis: A scoping review

“…Applying the inclusion/exclusion criteria to titles/abstracts resulted in 44 articles for full‐text screening. Once the full text of those articles was screened, 25 RCTs (1.8% of those identified by the search process) met all inclusion criteria . We also included five systematic reviews for our review of generic HRQOL …”

“…Study and participant characteristics are summarized in Table . Of the 25 RCTs included in this review, 13 studies investigated the effect of aerobic exercise (11 intradialytic and 3 home‐based interventions) . Seven studies looked at the effect of intradialytic resistance exercise .…”

“…The effects of exercise on a range of PROs were reported (see Table ), including anxiety (3 studies); depression (6 studies); HRQOL (19 studies); disability/activities of daily living (2 studies); dialysis‐related symptom frequency (6 studies); self‐reported physical activity level (4 studies); sleep (2 studies) . A single study also investigated the effects of exercise on stage of change in terms of readiness for exercise participation, perceived fitness, and physical self‐efficacy .…”

“…Of the 25 RCTs included in this review, 13 studies investigated the effect of aerobic exercise (11 intradialytic and 3 home-based interventions). 11,14,15,17,19,21,[23][24][25]29,30,33,35 Seven studies looked at the effect of intradialytic resistance exercise. [12][13][14][15]20,31,33 Seven studies implemented an intervention combining both aerobic and resistance exercise (six intradialytic; 14,16,22,28,33,34 one facility based 26 ) and two of these studies had a total of four arms.…”

“…14,33 Finally, two studies investigated exercise and rehabilitation counseling programs which incorporated counseling regarding home-based physical activity programming. 18,32 The effects of exercise on a range of PROs were reported (see Table 1), including anxiety (3 studies); 11,14,22 depression (6 studies); 12,14,19,22,28,34 HRQOL (19 studies); 12,13,[15][16][17][18]20,[23][24][25][26][27][28][29][30][31][33][34][35] disability/ activities of daily living (2 studies); 13,18 dialysis-related symptom frequency (6 studies); 11,16,18,19,27,34 self-reported physical activity level (4 studies); 12,13,21,32 sleep (2 studies). 11,19 A single study also investigated the effects of exercise on stage of change in terms...…”