Effectiveness of Laparoscopic Cholecystectomy in Patients with Gallbladder Stones with Chronic Cholecystitis

Abstract

Objective. To assess the effectiveness of laparoscopic cholecystectomy in patients with gallbladder stones and chronic cholecystitis. Methods. From July 2018 to January 2020, 90 patients with gallbladder stones and chronic cholecystitis assessed for eligibility were recruited and concurrently assigned (1 : 1) to receive either small-incision cholecystectomy (observation group) or laparoscopic cholecystectomy (experimental group). Outcome measures included operation time, intraoperative bleeding volume, postoperative hospital stay, c-reactive protein (CRP), interleukin (IL)-6, tumor necrosis factor-α (TNF-α), gastrin (GAS), vasoactive intestinal peptide (VIP), motilin (MOT), and adverse events. Results. Patients given laparoscopic cholecystectomy showed lower levels of operation-related indices versus those receiving small-incision cholecystectomy ( P < 0.05 ). Laparoscopic cholecystectomy resulted in lower postoperative levels of CRP, IL-6, and TNF-α in the patients versus small-incision cholecystectomy ( P < 0.05 ). Patients receiving laparoscopic cholecystectomy showed better GAS, VIP, and MOT levels than those receiving small-incision cholecystectomy ( P < 0.05 ). The eligible patients after laparoscopic cholecystectomy had a significantly lower incidence of adverse events versus those after small-incision cholecystectomy ( P < 0.05 ). Conclusion. Laparoscopic cholecystectomy effectively shortens the operative time and length of hospital stay in patients with gallbladder stones and chronic cholecystitis, reduces intraoperative bleeding, attenuates the inflammatory response, and enhances the gastrointestinal function, with less surgical trauma and high safety. Clinical trials are, however, required prior to promotion.

An Indian surgeon's perspective on management of asymptomatic gallstones

“…With the advancement in medical sciences and technologies, minimally invasive surgeries have replaced the conventional open surgeries. 6 Cholecystectomies are being performed laparoscopically rather than open methods due to lower risks of wound infection, faster recovery rates, and shorter duration of hospital stays. 7 However, in asymptomatic patients, the added risk of complications including bile duct injury from laparoscopic cholecystectomy must be balanced against the potential benefit of the treatment.…”

“…The current gold standard treatment for symptomatic gallstone disease is laparoscopic cholecystectomy, which is the minimally invasive procedure for the surgical removal of gallbladder. With the advancement in medical sciences and technologies, minimally invasive surgeries have replaced the conventional open surgeries 6 . Cholecystectomies are being performed laparoscopically rather than open methods due to lower risks of wound infection, faster recovery rates, and shorter duration of hospital stays 7 .…”

Minimally invasive procedures in diagnostics and treatment of complications following cholecystectomy in acute cholecystitis.

“…Одним из ярких примеров внедрения технологических усовершенствований в сферу практической медицины является масштабное применение малоинвазивных хирургических вмешательств. Их внедрение в различных областях хирургии как в плановом, так и в экстренном порядке, базирующееся на современных методах визуализации, диссекции и реконструкции целостности биологических тканей минимизировало продолжительность госпитализации и послеоперационную летальность, что в результате позволило значительно улучшить качество медицинского лечения во всех странах мира [6][7][8][9][10][11][12][13]. В настоящее время открытая холецистэктомия продолжает выполняться во многих регионах мира и показана в случаях, если осуществление лапароскопической холецистэктомии невозможно по каким-либо причинам [14][15][16].…”

Retracted: Effectiveness of Laparoscopic Cholecystectomy in Patients with Gallbladder Stones with Chronic Cholecystitis

“…This article has been retracted by Hindawi following an investigation undertaken by the publisher [ 1 ]. This investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process: Discrepancies in scope Discrepancies in the description of the research reported Discrepancies between the availability of data and the research described Inappropriate citations Incoherent, meaningless and/or irrelevant content included in the article Peer-review manipulation …”

“…Tis article has been retracted by Hindawi following an investigation undertaken by the publisher [1]. Tis investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process:…”