Effectiveness of long-lasting insecticidal nets in prevention of malaria among individuals visiting health centres in Ziway-Dugda District, Ethiopia: matched case–control study

Wubishet, Mesfin Kelkile; Berhe, Gebretsadik; Adissu, Alefech; Tafa, Mesfin

doi:10.1186/s12936-021-03833-9

Cited by 17 publications

(11 citation statements)

References 30 publications

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“…Drawing from existing literature, we incorporate into our scenario analysis the intervention’s implementation, durability and efficiency. Notably, LLINs exhibit an efficiency rate of approximately 77%, decreasing malaria prevalence by about 77%, and have a lifespan of three years [46, 47, 48]. Based on this information, we set b and c at 0.8 to mimic a similarly high efficacy of LLINs.…”

Section: Numerical Resultsmentioning

confidence: 99%

Mathematical assessment of the role of intervention programs for malaria control

Korsah,

Johnston,

Tiedje

et al. 2023

Preprint

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Malaria remains a global health problem despite the many attempts to control and eradicate it. There is an urgent need to understand the current transmission dynamics of malaria and to determine the interventions necessary to control malaria. In this paper, we seek to develop a fit-for-purpose mathematical model to assess the interventions needed to control malaria in an endemic setting. To achieve this, we formulate a malaria transmission model to analyse the spread of malaria in the presence of interventions. A sensitivity analysis of the model is performed to determine the relative impact of the model parameters on disease transmission. We explore how existing variations in the recruitment and management of intervention strategies affect malaria transmission. Results obtained from the study imply that the discontinuation of existing interventions has a significant effect on malaria prevalence. Thus, the maintenance of interventions is imperative for malaria elimination and eradication. In a scenario study aimed at assessing the impact of long-lasting insecticidal nets (LLINs), indoor residual spraying (IRS), and localized individual measures, our findings indicate that increased LLINs utilization and extended IRS coverage (with longer-lasting insecticides) cause a more pronounced reduction in symptomatic malaria prevalence compared to a reduced LLINs utilization and shorter IRS coverage. Additionally, our study demonstrates the impact of localized preventive measures in mitigating the spread of malaria when compared to the absence of interventions.

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Section: Numerical Resultsmentioning

confidence: 99%

Mathematical assessment of the role of intervention programs for malaria control

Korsah,

Johnston,

Tiedje

et al. 2023

Preprint

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“…As cost effective as the current interventions are, these interventions have limitations, and the implementation of pgSIT has the potential to completely eliminate malaria in the region. The current methods are quite cost effective, but they are likely at their peak capability due to the limitations of low compliance rates, growing insecticide resistance, and the lack of outdoor interventions (Wubishet et al 2021; Fru et al 2021; Aweis et al 2023; Kayedi et al 2007). These issues make it highly unlikely that these approaches could eliminate malaria in these regions, even if the investment is increased.…”

Section: Resultsmentioning

confidence: 99%

Cost-effectiveness of Precision Guided SIT for Control ofAnopheles gambiaein the Upper River Region, The Gambia

Gendron,

Raban,

Mondal

et al. 2023

Preprint

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Precision-guided sterile insect technique (pgSIT) is an extremely promising vector control intervention that can reduce and potentially eliminate the unacceptable malaria burden, particularly in sub-Saharan Africa. Here we explore the cost effectiveness of using this approach in Africa using mathematical modeling and economical analysis. Overall, we find that pgSIT represents a cost-effective and promising approach to A. gambiae control in The Gambia, with the potential to deliver significant economic and social benefits.

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“…The study noted usage rates of LLIN/IRS that were less than desirable, suggesting a need to scale up programmes and interventions targeting improved effective use of such. 10 , 39 , 40 On the other hand, the lack of association between malaria RDT positivity rate and the usage of LLIN/IRS suggests a need for review of the effectiveness of the strategy. 41 This may be due to the fact that the effectiveness of vector control strategies such as LLIN depends on certain vector parameters which may be different across regions or may change over time within the same region.…”

Section: Discussionmentioning

confidence: 99%

Malaria among the elderly in five communities of Osun East district, Southwest Nigeria: Prevalence and association with non-communicable diseases

et al. 2023

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Objective: The level of immunity against pathogens decreases with old age. As a result, the elderly may be regarded to be at increased risk of malaria morbidity and fatality. There is paucity of studies on malaria among the elderly population in Osun East district, Southwest Nigeria. This study aimed to determine the prevalence of malaria and its association with medical comorbidities among the elderly. Methods: A descriptive cross-sectional study was carried out, which involved 972 adult residents of five communities in Osun State, who were selected using a multistage random sampling technique. Data was collected with aid of a structured questionnaire. The medical history of respondents and anthropometric measures were obtained. The presence of malaria parasitaemia in the respondents was determined by rapid diagnostic test (RDT). Appropriate descriptive and inferential analyses were done. Results: Out of the 972 respondents, 504 (51.9%) were 60 years and above. The overall prevalence of malaria RDT positivity was 4%. The positivity rate was higher among the elderly (4.6%) compared to those less than 60 years (3.4%), albeit not statistically significant ( p = 0.36). Among these elderlies, 52.6% and 16.1% used insecticide-treated nets and insecticide sprays, respectively. There was no association between the prevalence of malaria positivity and comorbid conditions, such as hypertension ( p = 0.37), overweight/obesity ( p = 0.77), or diabetes ( p = 0.15). Malaria positivity rate was also not significantly associated with the use of insecticide-treated nets ( p = 0.64) or insecticide sprays ( p = 0.45). Conclusion: The malaria positivity rate was higher among the elderly in the study area, although not statistically significant. The prevalence was not associated with comorbid medical conditions.

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Effectiveness of long-lasting insecticidal nets in prevention of malaria among individuals visiting health centres in Ziway-Dugda District, Ethiopia: matched case–control study

Cited by 17 publications

References 30 publications

Mathematical assessment of the role of intervention programs for malaria control

Mathematical assessment of the role of intervention programs for malaria control

Cost-effectiveness of Precision Guided SIT for Control ofAnopheles gambiaein the Upper River Region, The Gambia

Malaria among the elderly in five communities of Osun East district, Southwest Nigeria: Prevalence and association with non-communicable diseases

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