Effectiveness of Magnesium Sulfate With Glycerine Versus Cold Compress on Patients With Peripheral Intravenous Cannula Induced Phlebitis

Abstract

Objective: The objective of the study was to determine the effectiveness of magnesium sulfate with glycerine versus cold compress on patients with a peripheral intravenous cannula (PIVC) induced phlebitis. Methods: A quasi-experimental pre-test post-test study on 60 subjects, 30 in each group, with interventions magnesium sulfate with glycerine application to one group and cold compress to another group of patients with PIVC induced phlebitis was done in a tertiary care hospital, Kerala. Purposive sampling with random allocation of subjects to each group was done. A standardized visual infusion phlebitis (VIP) scale was used to assess the severity of PIVC induced phlebitis. Results: Both magnesium sulfate with glycerine (MD=2.1, t29=16.16, p<0.001) and cold compress (MD=1.6, t29=17.59, p<0.001) were found to be effective in reducing the PIVC induced phlebitis. The difference in post-interventional VIP scores between application of magnesium sulfate with glycerine and cold compress was found to be statistically significant (F(1,57)=5.362*, p<0.05). The mean post-interventional VIP scores of magnesium sulfate with glycerine application (0.059) was less than the cold compress (0.274). The study concluded that magnesium sulfate with glycerine application was more effective than cold compress for treating PIVC induced phlebitis. Conclusion: The study highlights the significance of exploring the foremost effective intervention out of the many good practices currently in use in the prevention and management of phlebitis.

Effectiveness of Glycerin Magnesium Sulphate Versus Heparin Benzyl Nicotinate Application Among Children with Phlebitis

“…Other various studies also agree that there is a significant decrease in post test score after magnesium sulphate application in the treatment of phlebitis in adults. [13][14][15]21,22 Another study in China, showed similar findings that phlebitis was significantly reduced by external application of magnesium sulphate. 16 The study shows a significant difference in reduction of VIP score at 12 hours (p = 0.403) and 24 hours (p = 0.002) in the control group.…”

Practical view of the topical treatment of peripheral venous catheter‐related phlebitis: A scoping review

“…Concerning the mode of administration, some studies (Basu et al, 2017; Selva Grace et al, 2020; Soloman et al, 2015; Yadav et al, 2016; Yambem et al, 2015) provided no information In this respect, magnesium sulphate‐glycerine was administered in solution form (Amuda et al, 2019; Packialakshmi & Vidhya, 2017; Varghese & Moly, 2018) through compress and bandage 2 or 3 times a day for 2 or 3 days, in ointment form 3 times a day for 3 days (Jayabharathi, 2015; Rukhsana et al, 2016), and with a bandage and raised limb twice a day for 2 days (Ravindra & Patel Krupa, 2015). Magnesium sulphate was applied every 2 h for 2 days in solution form with a compress, and the limb was raised, wrapped in plastic and immobilised (Wan, 2018), or it was applied in ointment form with a gauze dressing twice or 3 times a day for 2 or 3 days (Sharma, 2016; Vidhya, 2017).…”

“…Of the 9 studies which considered anti‐inflammatories, 7 reported an improvement in symptoms: magnesium sulphate‐glycerine (Packialakshmi & Vidhya, 2017; Ravindra & Patel Krupa, 2015), vs. the application of cold (Varghese & Moly, 2018) and vs. heparinoids (Amuda et al, 2019; Jayabharathi, 2015; Selva Grace et al, 2020; Yambem et al, 2015). Magnesium sulphate without glycerine obtained a better response than heparinoids and the application of cold (Sharma, 2016) and aloe vera (Vidhya, 2017).…”

“…As for the mode of administration, cold was applied through ice packs or compresses at <15°C (Jayabharathi, 2015; Rukhsana et al, 2016; Sharma, 2016; Varghese & Moly, 2018), warmth through warm water compresses at 45°C (Hidayah et al, 2017; Jourabloo et al, 2017), and heat also through compresses but without specifying the temperature (Shilpa et al, 2015). The treatments were applied for 5–20 min every 8 or 12 h during 2–3 days.…”

“…the application of cold (Varghese & Moly, 2018) and vs. heparinoids (Amuda et al, 2019;Jayabharathi, 2015;Selva Grace et al, 2020;Yambem et al, 2015). Magnesium sulphate without glycerine obtained a better response than heparinoids and the application of cold (Sharma, 2016) and aloe vera (Vidhya, 2017).…”