Effectiveness of Methadone Maintenance Therapy and Improvement in Quality of Life Following a Decade of Implementation

Fei, Joni Teoh Bing; Yee, Anne; Habil, Mohamad Hussain; Danaee, Mahmoud

doi:10.1016/j.jsat.2016.07.006

Cited by 52 publications

(28 citation statements)

References 34 publications

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“…The lack of social relationships can be explained by the fact that people using illicit drug have to take a long time to regain trust in their family and other relatives [34]. The reliability of the WHOQoL-BREF in this area of study has been demonstrated previously by several longitudinal studies on MMT in Vietnam and other parts of Asia, all of which demonstrate improvements in QoL using the WHOQoL-BREF [18,[35][36][37]. Findings from our study on the improvement of quality of life after 12months of the MMT program are critical evidence that demonstrates the effectiveness of MMT in enhancing the health status of illicit drug users.…”

Section: Discussionmentioning

confidence: 72%

Changes in quality of life and its associated factors among illicit drug users in Vietnamese mountainous provinces: a 12-month follow-up study

Tran

Moir

Nguyen

et al. 2020

Subst Abuse Treat Prev Policy

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Background: Sustainability of methadone maintenance treatment (MMT) program involves regularly assessing its impact on health and social outcomes of drug users in different settings, particularly in disadvantaged areas. In this study, we evaluated the change in quality of life (QoL), and identified associated factors amongst drug users over the course of 12-month MMT in Vietnamese mountainous provinces. Methods: We conducted a longitudinal study among patients from 6 MMT clinics in three mountainous provinces of Vietnam. At baseline, we screened 300 participants and after a 12-month treatment, 244 participants remained to involve in the study. World Health Organization Quality of Life short form instrument (WHOQOL-BREF) was used to measure the QoL of patients. The magnitude of the changes was extrapolated.Results: There were significant changes in all four dimensions of quality of life measured by WHOQoL-BREF between baseline and 12 months with the effect size ranged from 0.21 to 0.24. Increased age, being workers compared to unemployment and having health problems or comorbidities were positively related to reduced scores of QoL. Conclusions: To conclude, we observed a significant increase in the QoL level regarding physical, psychological, social relationships and environmental aspects among people who used drug after 12 months of MMT. Findings from this study emphasize the role of continuously receiving MMT treatment among people using drugs to enhance their QoL.

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Section: Discussionmentioning

confidence: 72%

Changes in quality of life and its associated factors among illicit drug users in Vietnamese mountainous provinces: a 12-month follow-up study

Tran

Moir

Nguyen

et al. 2020

Subst Abuse Treat Prev Policy

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“…Methadone itself does not induce intoxication, and tolerance to it develops slowly, thus allowing patients to be on MMT for longer periods of time 41. Fei Bing et al42 found that MMT can significantly improve the quality of life: measured by reduction in heroin use, injecting practices, crime, and improvement in social functioning and physical symptoms.…”

Section: Treatment Optionsmentioning

confidence: 99%

New developments in managing opioid addiction: impact of a subdermal buprenorphine implant

Itzoe¹,

Guarnieri²

2017

DDDT

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Opioid addiction to prescription and illicit drugs is a serious and growing problem. In the US alone, >2.4 million people suffer from opioid use disorder. Government and pharmaceutical agencies have begun to address this crisis with recently released and revised task forces and medication-assisted therapies (MAT). For decades, oral or intravenous (IV) MATs have helped patients in their recovery by administration of opioid agonists (methadone, buprenorphine, oxycodone), antagonists (naltrexone, naloxone), and combinations of the two (buprenorphine/naloxone). While shown to be successful, particularly when combined with psychological counseling, oral and IV forms of treatment come with constraints and challenges. Patients can become addicted to the agonists themselves, and there is increased risk for diversion, abuse, or missed dosages. Consequently, long-acting implants have begun to be developed as a potentially preferable method of agonist delivery. To date, the newest implant approved by the US Food and Drug Administration (May 2016) is Probuphine®, which delivers steady-state levels of buprenorphine over the course of 6 months. Numerous studies have demonstrated its efficacy and safety. Yet, implants come with their own risks such as surgical site irritation, possible movement, and protrusion of implant out of skin. This review introduces the opioid abuse epidemic, examines existing medications used for therapy, and highlights Probuphine as a new treatment option. Costs associated with MATs are also discussed.

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“…In The same context, the previous study of Malaysia carried out on 96 patients treated by methadone has shown that there is not a significant association of quality of life according to the period of treatment (Teoh Bing Fei et al, 2016).…”

Section: Discussionmentioning

confidence: 90%

“…Also, patients who are maintained under treatment by methadone showed an improvement in the quality of life in all areas including the social relations and the state of physical health (Teoh Bing Fei et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

“…A range of public is not sufficiently aware of the effectiveness of this treatment, although it is beneficial for public health and work integration, for reducing the risk of HIV infection as well as for crime (Mark, & Parrino, 1992). In particular, it helps improve the quality of life of patients regarding professional and family integration (Teoh Bing Fei et al, 2016). Despite the widely documented success in treating chronic drug dependence for more than twenty-five years, methadone maintenance treatment has survived tough years of inadequate funding and some negative public perception.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Evolution of the Health Status and Quality of Life of Heroin Addicts Treated with Methadone in the City of Tangier, Morocco

Idrissi¹,

Ahami²,

Ghaihlan³

et al. 2018

PSYCH

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Opiate substitution treatment with methadone (STM) is one of the most effective means of treating heroin addiction. It presents itself as a beneficial treatment for health, and insertion into work but also for the reduction of infectious risks and crime. Improving the quality of life of patients during treatment including social and relational life and somatic state has been considered by some research to be more important than abstinence from the substance itself. The objective of this study is to evaluate the effect of methadone treatment on the quality of life of 101 drug-addicted patients in a health center in Tangier city, including the possible improvement of their socio-professional, relational and somatic state, using the characters of the official questionnaires of request of cure and based on the multidisciplinary method of the ASI (Addiction Severity Index). Our questionnaire included a rubric for sociodemographic data and another one for the evaluation of the impact of this treatment on the somatic, socio-professional and relational state of the patients according to two periods: before and after the treatment, and according to the duration of the treatment. The results obtained showed an improvement in the somatic state including weight, sleep, nutritional status and socio-occupational and relational status after inclusion in treatment.

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Effectiveness of Methadone Maintenance Therapy and Improvement in Quality of Life Following a Decade of Implementation

Cited by 52 publications

References 34 publications

Changes in quality of life and its associated factors among illicit drug users in Vietnamese mountainous provinces: a 12-month follow-up study

Changes in quality of life and its associated factors among illicit drug users in Vietnamese mountainous provinces: a 12-month follow-up study

New developments in managing opioid addiction: impact of a subdermal buprenorphine implant

The Evolution of the Health Status and Quality of Life of Heroin Addicts Treated with Methadone in the City of Tangier, Morocco

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