“…24 Additionally, exercise is a well-established adjunct therapy for acute mobility disorders, contributing to pain reduction and the improvement or restoration of functional activities. 25 A recent study suggests that combining CAT with active exercise improves pain and dysfunction in patients with ALS in a short period, but with limitations such as small sample size and insufficient blinding. 26 Therefore, the immediate efficacy of this combined therapy for ALS remains unclear, necessitating further validation.…”