Effectiveness of non-pharmacological treatments for vestibular and oculomotor dysfunction in patients with persistent post-concussive symptoms: protocol for a systematic review and meta-analysis

Sheeba, Stella R; Cavaleri, Rocco; Summers, Simon J; Browne, Cherylea J.

doi:10.1136/bmjopen-2022-066634

Cited by 1 publication

(1 citation statement)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For most individuals who suffer a concussion, symptoms resolve within 2–4 weeks after injury; however, a minority of patients continue to experience persistent symptoms, which appear to be the result of ongoing impairment of ocular motility attributed to ongoing neuronal dysfunction in the brain, biomechanical dysfunction in the cervical spine, and dysfunction in the vestibular system [ 12 , 13 , 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of Cervical Spinal Manipulation on Saccadic Eye Movements

Klotzek,

Jemni,

Groves

et al. 2024

Brain Sciences

View full text Add to dashboard Cite

Quantifying saccadic eye movements can assist in identifying dysfunctional brain networks in both healthy and diseased people. Infrared Oculography is a simple and non-invasive approach to capturing and quantifying saccades, providing information that might aid in diagnosis and outcome assessments. The effect of spinal manipulation on quantified saccadic performance parameters has not been fully studied despite known post-manipulative effects on the brain and brainstem regions controlling them. This case study investigates spinal manipulation’s immediate and long-term effects on saccadic eye movements by quantifying the saccades of a male patient diagnosed with post-concussion syndrome. The patient performed horizontal saccades that were quantified before and immediately following cervical spinal manipulation both at the case study’s start and following a 2-week interim, during which the subject received six manipulative treatments. Immediate and long-term post-manipulative effects were observed, and the results revealed various post-manipulative effects across all quantified parameters in addition to between right and leftward saccades. The immediate post-manipulative effect was greatest at the case study’s onset, while the long-term right and leftward saccadic symmetry were most affected. The observations in this case study demonstrate that cervical spinal manipulation influences saccadic eye movements, providing new insights into its central neurological effects and therapeutic applications beyond its most commonly known use in pain management. More importantly, it encourages scientists to undertake further clinical investigations on wider scales.

show abstract