Effectiveness of Parenteral Iron Therapy in the Real-world Setting: A Retrospective Analysis

Abstract

Iron deficiency constitutes a significant economic burden to society, increasing health care resource use, reduced work productivity and absenteeism from work [12,13].

Efficacy and Safety of Ferric Carboxymaltose in the Management of Iron Deficiency Anemia: A Multi-Center Real-World Study from India

“… 20 , 28 Real-world studies have reported a significant increase in Hb levels post FCM administration; 2.6 g/dL at 4 weeks; 21 Hb increase of ≥2 g/dL and ≥3 g/dL were attained by 41% and 20% of subjects, respectively, at 6 weeks; 22 normalized Hb ≤1 year. 29 In our study, Hb improved significantly at week 4 across the study population, and irrespective of the IDA severity (increase of 1.89 g/dL in mild, 2.63 g/dL in moderate, and 3.31 g/dL in severe anemia) (P < 0.001 for all).…”

“… 41 A retrospective real-world study of 2966 adults with IDA showed that patients treated with FCM were significantly more likely to receive their full iron store repletion dose within three weeks than patients treated with ferumoxytol (P < 0.001) or with other parenteral iron preparations, such as iron dextran, iron sucrose, and sodium ferric gluconate in sucrose (P < 0.001 for all). 29 Patients on FCM were significantly more likely to have achieved the desired Hb levels within a year of index injection than those on ferumoxytol (P < 0.001). Patients on FCM required significantly fewer outpatient visits within that year than patients on ferumoxytol or with other parenteral iron preparations (P ≤ 0.001 for all comparisons).…”

“…Patients on FCM required significantly fewer outpatient visits within that year than patients on ferumoxytol or with other parenteral iron preparations (P ≤ 0.001 for all comparisons). 29 …”