Effectiveness of Pharmacist–Physician Collaborative Management for Patients With Idiopathic Pulmonary Fibrosis Receiving Pirfenidone

Satsuma, Yukari; Ikesue, Hiroaki; Kusuda, Kaori; Maeda, Mami; Muroi, Nobuyuki; Mori, Ryohei; Kogo, Mariko; Hirabayashi, Ryosuke; Nagata, Kazuma; Nakagawa, Atsushi; Tachikawa, Ryo; Tomii, Keisuke; Hashida, Tohru

doi:10.3389/fphar.2020.529654

Cited by 7 publications

(9 citation statements)

References 32 publications

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“…Four studies reported better medication adherence (three medication support programmes [ 39 , 77 , 89 ]; one home monitoring programme [ 40 ]). One palliative care programme reported increased use of antifibrotic therapy [ 58 ].…”

Section: Resultsmentioning

confidence: 99%

Self-management interventions for people with pulmonary fibrosis: a scoping review

Lee,

Tikellis,

Dowman

et al. 2023

Eur Respir Rev

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BackgroundThe most effective method for encouraging self-management in individuals with pulmonary fibrosis (PF) is unclear. This review aimed to identify common self-management components, the outcome measures used and the impact of these components in PF.MethodsA scoping review was conducted according to theJoanna Briggs Institute Manual for Evidence Synthesisusing Medline, Embase, PsychInfo, CINAHL and the Cochrane Central Register of Controlled Trials. Eligible studies included those with educational, behavioural or support components aimed at facilitating self-management among adults with PF and employed quantitative and/or qualitative methods.Results87 studies were included. Common self-management components included education (78%), managing physical symptoms (66%) and enhancing psychosocial wellbeing (54%). Components were predominantly delivered in a pulmonary rehabilitation setting (71%). No studies tested a PF-specific self-management package. Common outcome measures were 6-min walk distance (60%), St George's Respiratory Questionnaire (37%) and the Medical Research Council Dyspnoea scale (34%). Clinically significant improvements in these outcomes were seen in ≥50% of randomised controlled trials. Qualitative data highlighted the importance of healthcare professional and peer support and increased confidence in managing PF.ConclusionSelf-management components are commonly incorporated into pulmonary rehabilitation programmes rather than being offered as standalone packages. Future research should focus on testing PF-specific self-management packages and employ standardised outcome assessments that include self-efficacy and health-related behaviours.

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Section: Resultsmentioning

confidence: 99%

Self-management interventions for people with pulmonary fibrosis: a scoping review

Lee,

Tikellis,

Dowman

et al. 2023

Eur Respir Rev

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“…The value of pharmacist-led team care in pharmacotherapies has been demonstrated in numerous studies ( Yamamoto et al, 2018 ; Escudero-Vilaplana et al, 2020 ; Satsuma et al, 2020 ; Ji et al, 2021 ; Jia et al, 2021 ; Marzal-Alfaro et al, 2021 ; Miura et al, 2021 ; Xu et al, 2021 ). The results of this study revealed that pharmacist-urologist collaborative management can also improve care for patients with CRPC receiving enzalutamide in an ambulatory care setting.…”

Section: Discussionmentioning

confidence: 99%

“…Studies have demonstrated that patient-centered, multidisciplinary team care, which provides support, information, and empowerment to cancer patients receiving chemotherapy, is effective ( Pillay et al, 2016 ; Lutfiyya et al, 2019 ; Xie et al, 2021 ). In addition, we developed a pharmacist-physician collaborative management system for patients with idiopathic pulmonary fibrosis receiving pirfenidone treatment, and reported the efficacy of this approach ( Satsuma et al, 2020 ). Based on these, in October 2016, we developed an ambulatory care pharmacy practice that allows pharmacist–urologist collaboration for the management of patients with CRPC receiving ASIs, including enzalutamide.…”

Section: Introductionmentioning

confidence: 99%

Pharmacist-Urologist Collaborative Management Improves Clinical Outcomes in Patients With Castration-Resistant Prostate Cancer Receiving Enzalutamide

et al. 2022

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Background: Enzalutamide is useful for the treatment of castration-resistant prostate cancer (CRPC). Despite its usefulness, adverse events (AEs) sometimes force patients to discontinue treatment. To maximize patient care, we developed an ambulatory care pharmacy practice that allows collaboration between a pharmacist and urologist to manage patients with CRPC receiving enzalutamide. In this study, we investigated the efficacy of this collaborative management.Methods: A retrospective chart review of 103 patients with CRPC receiving enzalutamide in our hospital between May 2014 and December 2020 was performed. Our collaborative management was implemented in October 2016. Before being examined by urologists, patients visited the oncology pharmacy consultation room for a face-to-face consultation, wherein the oncology pharmacists assessed factors such as adherence to enzalutamide, any AEs and their grades, and provided their suggestions to the urologists. The time to enzalutamide discontinuation and prostate-specific antigen progression were compared between patients who started enzalutamide before (n = 41) and after (n = 62) the implementation of the collaborative management. A multivariate Cox regression analysis was performed to analyze the factors associated with enzalutamide discontinuation.Results: After implementing collaborative management, the pharmacists had 881 patient consultations. Among the 476 suggestions from pharmacists, 345 were accepted by urologists. The most frequent suggestion was supportive care in enzalutamide treatment (224 suggestions). Multivariate analysis showed that collaborative management [hazard ratio (HR) 0.53, 95% confidence interval (CI) 0.31–0.89, p = 0.017] and higher prostate-specific antigen (PSA; HR 2.41, 95% CI 1.36–4.28, p = 0.003) were significantly associated with enzalutamide discontinuation. The median time to discontinuation (18.9 vs. 7.6 months, p = 0.012), time to discontinuation due to AEs (not reached in both groups, p = 0.001), and time to PSA progression (13.3 vs. 5.8 months, p = 0.002) were all significantly longer in the after group.Conclusions: We implemented a pharmacist-urologist collaborative management program for outpatients with CRPC receiving enzalutamide. The results revealed that collaborative management was useful for prolonging the time to enzalutamide discontinuation.

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“…Specifically, a well-coordinated effort between doctors, nurses, and pharmacists can prevent medication errors, optimize therapeutic regimens, and ensure holistic patient care [ 6 , 7 ]. Hospital pharmacists are vital contributors to healthcare systems, working with doctors, nurses, and allied health professionals in diverse settings—from inpatient bedsides to emergency departments and outpatient clinics [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Multidisciplinary perspectives on roles of hospital pharmacists in tertiary settings: a qualitative study

Lee,

Koeper,

Johnson

et al. 2023

International Journal for Quality in Health Care

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Backgrounds In today’s complex healthcare landscape, exacerbated by resource constraints at various levels, optimisation of health professionals’ roles is becoming increasingly paramount. Interprofessional collaboration, underpinned by role recognition and teamwork, leads to improved patient and organisational outcomes. Hospital pharmacists play a pivotal role in multidisciplinary teams, and it is imperative to understand multidisciplinary viewpoints on hospital pharmacists’ roles to guide role prioritisation and organisational efficiency. However, no study extensively investigated multidisciplinary views on values of diverse pharmacist roles in tertiary settings. This study aims to address this gap by examining non-pharmacist health professionals’ views on hospital pharmacists’ roles, recognising their specialised niches as a crucial step towards optimising their roles and services in Australia and internationally. Methods Multiple focus group discussions and interviews were held via a virtual conferencing platform. Study participants were recruited using the study investigators’ professional networks who were non-pharmacist health professionals with experience working with pharmacists in hospital settings. Data was collected from transcripts of the focus group recordings, which were later summarised using descriptive statistics and thematic analysis. Overarching themes were categorised and mapped against work system models to conceptualise organisational implications of multidisciplinary feedback, linking them to patient and organisational outcomes. Results 27 health professionals participated across focus groups and interviews, with the majority of professions being doctors and nurses. Three major themes were identified as follows: (1) overarching perceptions regarding hospital pharmacists; (2) professional niches of hospital pharmacists and (3) future opportunities to optimise hospital pharmacy services. Valued professional niches included patient and health professional educators, transitions-of-care facilitators and quality use of medicines analysts. Conclusion The study highlights critical insights into hospital pharmacists’ roles in Australia, identifying their niche expertise as vital to healthcare efficiency and success. Based on multidisciplinary feedback, the study advocates for strategic role optimisation and targeted research for enhanced clinical, economic and organisational outcomes.

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Effectiveness of Pharmacist–Physician Collaborative Management for Patients With Idiopathic Pulmonary Fibrosis Receiving Pirfenidone

Cited by 7 publications

References 32 publications

Self-management interventions for people with pulmonary fibrosis: a scoping review

Self-management interventions for people with pulmonary fibrosis: a scoping review

Pharmacist-Urologist Collaborative Management Improves Clinical Outcomes in Patients With Castration-Resistant Prostate Cancer Receiving Enzalutamide

Multidisciplinary perspectives on roles of hospital pharmacists in tertiary settings: a qualitative study

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