Effectiveness of Platelet-Rich Plasma Treatment in Chondromalacia Patellae

Subaşı, Volkan

doi:10.5152/jarem.2017.1099

Cited by 2 publications

(2 citation statements)

References 16 publications

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“…HA and PRP (as well as its derivatives), however, have been extensively investigated in the literature for the treatment of musculoskeletal conditions of the knee, especially in terms of degenerative joint diseases [16,17]. Numerous studies [18][19][20][21][22][23][24][25][26][27][28][29] have demonstrated satisfactory outcomes associated with the application of both PRP and HA, although sometimes PRP may or may not prove to be slightly superior to HA. The effects elicited by PRP include cell recruitment, proliferation, differentiation, neovascularization, cytokine secretion, and inflammatory modulation [30].…”

Section: Gradementioning

confidence: 99%

The Synergistic Effects of Hyaluronic Acid and Platelet-Rich Plasma for Patellar Chondropathy

Costa,

Santos,

Martins

et al. 2023

Biomedicines

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Musculoskeletal disorders are increasingly prevalent worldwide, causing significant socioeconomic burdens and diminished quality of life. Notably, patellar chondropathy (PC) is among the most widespread conditions affecting joint structures, resulting in profound pain and disability. Hyaluronic acid (HA) and platelet-rich plasma (PRP) have emerged as reliable, effective, and minimally invasive alternatives. Continuous research spanning from laboratory settings to clinical applications demonstrates the numerous advantages of both products. These encompass lubrication, anti-inflammation, and stimulation of cellular behaviors linked to proliferation, differentiation, migration, and the release of essential growth factors. Cumulatively, these benefits support the rejuvenation of bone and cartilaginous tissues, which are otherwise compromised due to the prevailing degenerative and inflammatory responses characteristic of tissue damage. While existing literature delves into the physical, mechanical, and biological facets of these products, as well as their commercial variants and distinct clinical uses, there is limited discussion on their interconnected roles. We explore basic science concepts, product variations, and clinical strategies. This comprehensive examination provides physicians with an alternative insight into the pathophysiology of PC as well as biological mechanisms stimulated by both HA and PRP that contribute to tissue restoration.

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Section: Gradementioning

confidence: 99%

The Synergistic Effects of Hyaluronic Acid and Platelet-Rich Plasma for Patellar Chondropathy

Costa,

Santos,

Martins

et al. 2023

Biomedicines

View full text Add to dashboard Cite

show abstract

“…HA and PRP (as well as its derivatives), however, have been extensively investigated in the literature for the treatment of musculoskeletal conditions of the knee, especially in terms of degenerative joint diseases [14,15]. Numerous studies [16][17][18][19][20][21][22][23][24][25][26][27] have demonstrated satisfactory outcomes associated with the application of both PRP and HA, although sometimes PRP may or may not prove to be slightly superior to HA. The effects elicited by PRP include cell recruitment, proliferation, differentiation, neovascularization, cytokine secretion and inflammatory modulation [28].…”

Section: Introductionmentioning

confidence: 99%

The Synergistic Effects of Hyaluronic Acid and Platelet-Rich Plasma for Patellar Chondropathy

Costa,

Santos,

Martins

et al. 2023

Preprint

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Musculoskeletal disorders are increasingly prevalent worldwide, causing significant socioeconomic burdens and diminished quality of life. Notably, patellar chondropathy (PC) is among the most widespread conditions affecting the joint structures, resulting in profound pain and disability. Hyaluronic acid (HA) and platelet-rich plasma (PRP) have emerged as reliable, effective, and minimally invasive alternatives. Continuous research spanning from laboratory settings to clinical applications demonstrate the numerous advantages of both products. These encompass lubrication, anti-inflammation, and stimulation of cellular behaviors linked to proliferation, differentiation, migration, and the release of essential growth factors. Cumulatively, these benefits support the rejuvenation of bone and cartilaginous tissues, which are otherwise compromised due to the prevailing degenerative and inflammatory responses characteristic of tissue damage. While existing literature delves into the physical, mechanical, and biological facets of these products, as well as their commercial variants and distinct clinical uses, there is limited discussion on their interconnected roles. We explore basic science concepts, product variations, and clinical strategies. This comprehensive examination provides physicians with an alternative insight into the pathophysiology of PC as well as biological mechanisms stimulated by both HA and PRP that contribute to tissue restoration.

show abstract

Effectiveness of Platelet-Rich Plasma Treatment in Chondromalacia Patellae

Cited by 2 publications

References 16 publications

The Synergistic Effects of Hyaluronic Acid and Platelet-Rich Plasma for Patellar Chondropathy

The Synergistic Effects of Hyaluronic Acid and Platelet-Rich Plasma for Patellar Chondropathy

The Synergistic Effects of Hyaluronic Acid and Platelet-Rich Plasma for Patellar Chondropathy

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