“…Use of a moderate dose of long-acting gonadotropin appears to be as effective as daily gonadotropin (Pouwer, et al, 2015) in autologous oocyte cycles; a single injection of Corifollitropin alfa (150-180 mcg) in the first week of stimulation has been shown to increase donor's satisfaction (Requena, et al, 2013). Oral progestogens have been introduced to replace GnRHantagonist injections, both in donor cycles (Begueria, et al, 2019, Martinez, et al, 2019 and in treating infertile couples and have been found to be a more convenient and less expensive method for endogenous LH suppression with equivalent efficacy (Cui, et al, 2021). Although a recent systematic review found a lower incidence of OHSS with progesterone priming, higher requirement of gonadotropin stimulation (Cui, et al, 2021), and a RCT evidence of lower pregnancy rate among the oocyte recipients (Begueria, et al, 2019) cast doubt on the use of progesterone-primed protocols at present (Martinez, et al, 2021).…”