Effectiveness of Routine Ultrasonography in Detecting Fetal Structural Abnormalities in a Low-Risk Population

Chitty, Lyn S.; Hunt, Gaye H.; Moore, Jennifer A.; Lobb, Michael

doi:10.1097/00006254-199208000-00006

Cited by 49 publications

(77 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The low detection rates can lead to increased perinatal mortality and morbidity. It also causes a lot of anxiety to the family (12) . On the other hand RADIUS trial found no statistically significant effect on the rate of induced abortion (14) .…”

Section: Discussionmentioning

confidence: 99%

Role of Ultrasound as a Diagnostic Modality in Detecting Congenital Anomalies

Vinodh¹

2017

jmscr

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Role of Ultrasound as a Diagnostic Modality in Detecting Congenital Anomalies

Vinodh¹

2017

jmscr

View full text Add to dashboard Cite

“…Such studies show detection rates for fetal abnormalities in unselected obstetric populations ranging from 40.4% to 74.4%. [8][9][10][11] However, the use of an unselected population fails to take into account that a number of these pregnancies are at perceived increased risk. Likewise, clinical cause for concern may arise during pregnancy and result in an antenatal ultrasound being performed for some other reason.…”

Section: Discussionmentioning

confidence: 99%

A comparative study of routine versus selective fetal anomaly ultrasound scanning

Long

Sprigg

1998

J Med Screen

View full text Add to dashboard Cite

Objectives-To evaluate the cost-benefit of changing from selective (high risk) to routine ultrasound screening for fetal anomaly. Setting-Women booked by general practitioners for primary antenatal care at their local hospital. Methods-Prospective study of the 12 months before and after introduction of routine second trimester ultrasound for fetal anomaly at our institution. All congenital abnormalities, mode of detection, and outcome were recorded and a cost analysis of the programme attempted. Results-In the 12 months of selective (high risk) ultrasound policy, detailed second trimester scans were performed in 1007 (26%) pregnancies. In the 12 months of routine ultrasound anomaly screening, scans were performed in 3529 (93%) pregnancies. Routine ultrasound was the sole method of detection for 11 major and 18 less severe congenital abnormalities found in low risk pregnancies which would not previously have qualified for high risk ultrasound. In seven of these cases the parents opted for termination of pregnancy, with estimated savings on treatment and long term care of £1 015 546. The financial cost of providing the ultrasound screening service at our hospital for 12 months was calculated at £57 573 and the resulting financial benefit for the year was estimated at £957 973. Conclusion-Although it is recognised that many of the emotional and psychological costs and benefits of the service are diYcult to evaluate, routine fetal anomaly ultrasound would seem to be economically justifiable. The financial savings achieved at our hospital would translate into a potential annual saving for the National Health Service of nearly £170 million if screening were oVered in all hospitals in England and Wales. (J Med Screen 1998;5:6-10)

show abstract

“…Many reports on the eVectiveness of antenatal ultrasound diagnosis are from tertiary referral centres where high risk populations are screened. Few studies have reported on the eVectiveness of screening populations by routine (rather than targeted) ultrasound scans, [3][4][5][6] and the role of routine ultrasonography and its validity as a screening test for fetal malformation in a low risk population is still open to debate. 7 Of all congenital anomalies, neural tube defects (NTDs) are the easiest to identify prenatally.…”

mentioning

confidence: 99%

Evaluation of the prenatal diagnosis of neural tube defects by fetal ultrasonographic examination in different centres across Europe

et al. 2000

View full text Add to dashboard Cite

Objective-Evaluation of prenatal diagnosis of neural tube defects by ultrasound examination in unselected populations across Europe. Setting-Prenatal ultrasound units in areas that report to contributing congenital malformation registers. Methods-All cases with a suspected or confirmed neural tube defect and delivered within the 30 month study period were identified from 18 Congenital Malformation Registers from 11 European countries. Data on the pregnancy, prenatal scans, outcome of pregnancy, and information on diVerent screening policies for each country were analysed. Results-670 766 deliveries occurred in the area covered by the registers during the study period. A neural tube defect was diagnosed at delivery in 542 cases. In 84% of these, the lesion was isolated (166 anencephaly, 252 spina bifida, 35 encephalocele). Of the 166 isolated cases with anencephaly, 96% were correctly identified prenatally; one was missed on scan, two were wrongly diagnosed, and four were not scanned (sensitivity 98%). 84% of the prenatal diagnoses were made before 24 weeks' gestation; 86% of isolated anencephalic pregnancies were terminated. Of the 252 cases of isolated spina bifida, 171 (68%) were correctly identified prenatally; 66% of these before 24 weeks' gestation. The diagnosis was missed on scan in 60 cases and 21 were not scanned (sensitivity 75%). The mean reduction in birth prevalence because of termination of pregnancy for spina bifida was 49% (range 6-100%). There was a wide variation between centres in prenatal detection rate (33-100%), termination of pregnancy of prenatally diagnosed cases (17-100%), and gestation both at diagnosis and termination of pregnancy. Conclusion-A high prenatal detection rate for anencephaly was reported by all registers. There is a large variation in prenatal detection and termination rates for spina bifida between centres, reflecting diVerences both in policy and culture. (J Med Screen 2000;7:169-174)

show abstract

Effectiveness of Routine Ultrasonography in Detecting Fetal Structural Abnormalities in a Low-Risk Population

Cited by 49 publications

References 1 publication

Role of Ultrasound as a Diagnostic Modality in Detecting Congenital Anomalies

Role of Ultrasound as a Diagnostic Modality in Detecting Congenital Anomalies

A comparative study of routine versus selective fetal anomaly ultrasound scanning

Evaluation of the prenatal diagnosis of neural tube defects by fetal ultrasonographic examination in different centres across Europe

Contact Info

Product

Resources

About