Effectiveness of Salk Vaccine in Reducing Nonparalytic Poliomyelitis in a Large Urban Epidemic

the Kansas City cases. The clinical and epi¬ demiologic data were recorded on a standard form, which included the usual identifying in¬ formation.date of onset of illness, vaccination status, clinical diagnosis, 60-day muscle eval¬ uation, and the pertinent epidemiologic in¬ formation. The hospital charts provided the clinical data, and the patients or their relatives supplied the epidemiologic data. The nttinber of injections of Salk-type vaccine given up to 2 weeks before the onset of symptoms determined the vaccination status. The clinical classifica¬ tion was based on the presence or absence of significant muscle weakness at the time of the 60-day examination. The investigations included extensive etio¬ logical studies. The specimens consisted of feces, either stools or rectal swabs, or both, and paired serums. In addition, throat wash¬ ings were available on many of the Des Moines cases and on some of the Kansas City cases. Virus isolations and identifications were per¬ formed in monkey kidney monolayer cultures. Poliomyelitis antibodies were measured by the complement fixation (CF) test, and antibodies for other enteroviruses were assayed by the neutralization test. Detailed descriptions of the methods appear elsewhere (1-6). The vaccination status of the population was determined by household surveys conducted according to the methods described by Serfling and co-workers (7). Experienced statisticians in collaboration with local and State health department personnel supervised the surveys. Volunteers.Red Cross nurses, Gray Ladies, and Junior League members.performed the interviews in Des Moines; in Kansas City, in

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Effectiveness of Salk Vaccine in Reducing Nonparalytic Poliomyelitis in a Large Urban Epidemic

Cited by 2 publications

References 6 publications

An Outbreak of Poliomyelitis in a Partially Vaccinated Population

An Outbreak of Poliomyelitis in a Partially Vaccinated Population

The Changing Pattern of Poliomyelitis Observed in Two Urban Epidemics: Kansas City and Des Moines, 1959

Contact Info

Product

Resources

About