Effectiveness of silver diamine fluoride and glass ionomer cement combined with fluoride varnish in arresting dental caries among intellectually disabled individuals: A randomized controlled trial

Mendiratta, Mansi; Manjunath, BC; Kumar, Adarsh; Yadav, Vipul; Shyam, Radhey; Wig, Madhavi

doi:10.1111/scd.12607

Cited by 13 publications

(13 citation statements)

References 28 publications

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“…The quality of the included studies rated between level II and lV. Three RCT (one of them has two entrances for different types of outcomes) ( 21 – 24 ), one pragmatic controlled clinical trial ( 25 ), one prospective cohort study ( 26 ), one retrospective audit ( 27 ), and four retrospective cohort studies ( 28 – 31 ) reported the outcomes of different interventions that aimed to restore teeth affected by caries disease in patients with disability in time interval 2011–2022.…”

Section: Resultsmentioning

confidence: 99%

Management of dental caries lesions in patients with disabilities: Update of a systematic review

Molina

Zar²,

Dougall³

et al. 2022

Front. Oral. Health

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The aim of this systematic review was to update an existing review on the management of dental caries lesions in patients with disabilities so as to provide an up-to-date summary of the evidence. Randomized clinical trials and cohort studies related to preventive and restorative programmes for dental caries among people requiring special care, published in English, Spanish, Portuguese, French and German languages from February 1st 2011 to April 1st 2022, were retrieved from three databases (“updated review”). From the 1,105 titles identified using the search topic “Caries AND Disability”, 17 papers informed in the analyses: 6 referring to caries preventive strategies and 11 related to restorative care strategies. Most of these studies targeted children and adults with intellectual/physical disability, although preventive and therapeutic strategies were also reported for frail older adults and onchohematological patients. Fluorides in tablets, gels or varnishes forms and the use of xylitol as a sugar substitute were reported as effective approach to prevent the onset of caries in high-risk groups. Minimally intervention treatment options such as the Hall technique, the ART approach and the use of SDF for arresting caries, were deemed suitable and effective strategies for treating existing lesions in-office. In conclusion, in the past decade (2011–2022) an increased number of articles reported strategies to prevent and manage caries among people requiring special care. Although an array of preventive and therapeutic strategies for dental caries exists, more and better-quality clinical evidence is needed to offer guidance to inform policy and practice for special care dentistry.

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Section: Resultsmentioning

confidence: 99%

Management of dental caries lesions in patients with disabilities: Update of a systematic review

Molina

Zar²,

Dougall³

et al. 2022

Front. Oral. Health

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“…In this context, the use of nonaerosol‐generating minimally invasive procedures in clinical dental care is increasing. For all these reasons, there is a clear need to find effective, safe, and accessible alternatives for the treatment of caries lesions in these groups of patients (Crystal & Niederman, 2019 ; Gao et al, 2021 ; Mendiratta et al, 2021 ).…”

Section: Discussionmentioning

confidence: 99%

“…In the case of patients with SHCNs aged 0−18 years who present <3 caries lesions, if there is no pain, the choice of treatment will depend on the patient's ability to cooperate. In uncooperative children, we opt for simpler strategies such as SDF or SMART (Crystal et al, 2017 ; Mendiratta et al, 2021 ), while in those able to cooperate, the conventional treatment indicated in each case will be carried out at the hospital's outpatient clinics. Patients in this same group who present four or more carious lesions without painful symptoms undergo comprehensive treatment under GA.…”

Section: Discussionmentioning

confidence: 99%

The use of silver diamine fluoride in a children's hospital: Critical analysis and action protocol

Brunet‐Llobet

Auría‐Martín

González‐Chópite

et al. 2022

Clinical & Exp Dental Res

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Objectives The present critical analysis aims to propose an action protocol for the use of silver diamine fluoride (SDF) in pediatric patients in a hospital setting, especially for those who are currently awaiting hospital dental treatment under general anesthesia. Material and Methods A literature search was performed in the PubMed/MEDLINE from 2009 to 2021 using the search terms “silver diamine fluoride”, “pediatrics silver diamine fluoride”, “application silver diamine fluoride”, and “AND” ‐ combined with terms: “potassium iodide”, “properties”, “adverse effects”, “early childhood caries”, “patient with disability”, “management”, “special health care needs patient”. Articles that recorded the type of teeth, application protocol, the concentration of the product, and possible complications of the treatment were selected. Results Four hundred and sixteen related articles were obtained, of which 13 were finally chosen on the basis of the search criteria. The age at which the use of SDF was recommended ranged from the first year of life to 12 years, in most cases in primary teeth. The study populations varied in size from 53 to 799 patients. An analysis of the characteristics of SDF and its use in pediatric patients with dental caries was performed. The recommended concentration was 38% SDF, applied twice yearly. The main complication reported was staining. A decision algorithm was designed including SDF as an agent for caries control in patients attending the specific population of our hospital (divided into two groups: healthy children aged 0−4 years and patients with special health care needs (SHCNs) aged 0−18 years). Conclusions SDF therapy appears to be effective in the control of caries in pediatric patients. We propose an action protocol for patients with early childhood caries to reduce risk, complications, and the progression of lesions. The protocol is aimed especially at pediatric patients who also have some systemic pathology, disability, SHCNs, and/or behavioral difficulties.

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“…13 Mendiratta ve ark. 14 mental retarde çocuklarda yaptıkları randomize kontrollü bir çalışmada, bir gruba sadece bir kez GDF uygulamışlar, diğer gruba ise atravmatik restoratif tedavi ile kombine olarak florürlü vernik uygulamışlardır. Her iki uygulamanın çürük durdurma etkinliğinin benzer nitelikte olduğunu belirtmişlerdir.…”

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“…Her iki uygulamanın çürük durdurma etkinliğinin benzer nitelikte olduğunu belirtmişlerdir. 14 Çürüğü durdurmak için uygulama sayısı ve sıklığı konusunda fikir birliği yoktur. Çocuklarda kullanım şekline ilişkin kanıta dayalı kılavuzlar geliştirmek için daha ileri çalışmalar gereklidir.…”

unclassified

Çocuk Di̇ş Heki̇mli̇ği̇nde Gümüş Di̇ami̇n Florür Kullanimi

UÇAR

AKYILDIZ

2022

Selcuk Dental Journal

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Öz: Gümüş diamin florür (GDF); diamin gümüş iyonu ve florür iyonundan oluşan renksiz ve topikal olarak uygulanabilen alkalen bir çözeltidir. Gümüş iyonlarının antibakteriyel özelliği ile florun çürük önleyici etkileri birleştirilerek Japonya’da 1969’ların sonunda GDF geliştirilmiştir. 2014 yılında ise Amerikan Gıda ve İlaç Dairesi (U.S Food and Drug Administration, FDA) tarafından diş hassasiyeti tedavisi için onaylanmıştır. Ancak son zamanlarda anti-karyojenik özellikleri ve dental plak biyofilminin büyümesini inhibe etmesi nedeniyle çürük kontrolünde kullanılmaktadır. GDF içerisindeki gümüş (Ag) iyonları, Streptokok mutans’ın büyümesini inhibe etmekte ve dental plaktaki S.mutans’ın metabolik aktivitesini azaltmaktadır. GDF içerisindeki flor iyonları ise çürüğün ilerlemesini önlemektedir. Gümüş ve florun sinerjistik etkileri ile çürük sürecinin durdurulabileceği ve yeni lezyon gelişiminin önlenebileceği ileri sürülmüştür. Amerikan Pediatrik Diş Hekimleri Birliği; özel sağlık bakım ihtiyacı olan çocuklar da dahil olmak üzere çocuk ve ergenlerde çürük yönetimi için GDF kullanımını tavsiye etmektedir.Bu derlemenin amacı; gümüş diamin florürün özellikle çürük riski yüksek çocuklarda ve tedavi imkanının kısıtlı olduğu durumlarda restoratif materyallere alternatif olarak daha yaygın olarak kullanılmasını sağlamaktır. Abstract: Silver diamine fluoride is a colorless and topically applicable alkaline solution consisting of diamine silver ion and fluoride ion. SDF was developed in Japan in the late 1969 by combining the antibacterial properties of silver ions with the caries preventive effects of fluorine ions. In 2014, it was approved by the US Food and Drug Administration (U.S. Food and Drug Administration, FDA) for the treatment of tooth sensitivity. However, it has recently been used in the control of dental caries due to its anti-cariogenic properties and inhibition of dental plaque biofilm growth. Silver (Ag) ions in SDF inhibit the growth of Streptococcus mutans and reduce the metabolic activity of S.mutans in dental plaque. Fluorine ions in SDF prevent the progression of caries. It has been suggested that the caries process can be stopped and new caries lesion development can be prevented with the synergistic effects of silver and fluorine. The American Association of Pediatric Dentists recommends the use of SDF for caries management in children and adolescents, including children with special health care needs. The aim of this review is to ensure that silver diamine fluoride solution is used more widely as an alternative to restorative materials, especially in children with high caries risk and in cases where treatment possibilities are limited.

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Effectiveness of silver diamine fluoride and glass ionomer cement combined with fluoride varnish in arresting dental caries among intellectually disabled individuals: A randomized controlled trial

Cited by 13 publications

References 28 publications

Management of dental caries lesions in patients with disabilities: Update of a systematic review

Management of dental caries lesions in patients with disabilities: Update of a systematic review

The use of silver diamine fluoride in a children's hospital: Critical analysis and action protocol

Çocuk Di̇ş Heki̇mli̇ği̇nde Gümüş Di̇ami̇n Florür Kullanimi

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