Effectiveness of skin protection measures in prevention of occupational hand eczema: results of a prospective randomized controlled trial over a follow-up period of 1 year

Kütting, Birgitta; Baumeister, Thomas; Weistenhöfer, Wobbeke; Pfahlberg, Annette; Uter, Wolfgang; Drexler, Hans

doi:10.1111/j.1365-2133.2009.09485.x

Cited by 87 publications

(66 citation statements)

References 28 publications

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“…Based on the HEROS results, significant differences between smokers and nonsmokers were observed only for erythema and vesicles (table 2). These results were not influenced by the intervention of the aforementioned study [32], and there was no association between smoking status and intervention effect. At the 1-year follow-up, only 3 subjects, 2 of them smokers, reported that they had been unable to work in the past year and a total of 13 subjects reported current topical application of steroids on both hands.…”

Section: Resultsmentioning

confidence: 49%

“…All participants gave their informed consent to take part in a standardized interview and a dermatological examination of their hands. A subgroup of 1,020 male metal workers (406 smokers and 614 nonsmokers) which fulfilled our inclusion criteria for a recently published intervention study [32] gave their written informed consent to be followed-up for 1 year. The study design was approved by the local ethics committee of the University of Erlangen-Nuremberg.…”

Section: Methodsmentioning

confidence: 99%

“…In order to obtain objective – almost observer-independent [32] – results, the HEROS [34], a quantitative skin score, had been used. The score comprised all eruptions and physiologic abnormalities (e.g.…”

Section: Methodsmentioning

confidence: 99%

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Does Smoking Have a Significant Impact on Early Irritant Hand Dermatitis in Metal Workers?

Kütting

Uter²,

Weistenhöfer³

et al. 2011

Dermatology

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Background: Although they know the long-term complications of smoking, many smokers require additional motivation for entering a smoking cessation programme. At the same time, smoking is considered a possible promoting factor for various skin diseases. Objective: The present study assesses the impact of smoking on occupational hand dermatitis in a high-risk population. Material and Methods: 1,355 metal workers, 97.3% of them shift workers, took part in a standardized interview and a dermatological examination of their hands. A subgroup of 1,020 males was willing to be followed-up for 1 year. Of those, 78.3% could be included in the final assessment. Results: Compared to the general German adult population the percentage of smokers was increased (41.7% at baseline). Probably due to self-selection bias and to a higher drop-out rate, the proportion of smokers was significantly lower at follow-up. Compared to nonsmokers, smokers had significantly higher score values for both erythematous lesions and vesicles. Conclusion: The present data might give additional support for occupational physicians or dermatologists to convince workers to quit smoking.

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Section: Resultsmentioning

confidence: 49%

Section: Methodsmentioning

confidence: 99%

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Does Smoking Have a Significant Impact on Early Irritant Hand Dermatitis in Metal Workers?

Kütting

Uter²,

Weistenhöfer³

et al. 2011

Dermatology

Self Cite

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“…They showed that the skin protection programme (using BCs and skin care creams) is effective as well as the use of BCs alone, contrary to moisturizers alone, but the best protective effect was obtained by combining BCs and moisturizers. Kütting et al [59] underline the contrast with the results of an Austrian prospective 4-armed randomized controlled trial on 485 of 1,006 workers coming from building (n = 198) and timber (n = 287) industries, followed over 1 year, in which each subject was assessed by clinical hand dermatitis categorization, transepidermal water loss and subjective perception. None of the 4 groups showed a protective effect on dermatitis.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of Barrier Creams against Irritant Contact Dermatitis

Mostosi

Simonart

2016

Dermatology

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Introduction: Skin tissue is frequently exposed to various irritant substances in the workplace, particularly in wet work, which can lead to the development of occupational contact dermatitis. ‘Barrier' creams (BCs) are well known, and their applications are still the subject of many studies and controversies. Methods: We searched all controlled trials investigating BCs against cutaneous irritants in humans published between 1956 and December 2014 from MEDLINE, PubMed, reference lists and existing reviews. Results: Thirty-nine studies about the effects of BCs against skin irritants in humans were selected. Among these, 27 trials in healthy volunteers were found to show many differences with regard to BCs and irritants used, their quantities, test locations, procedures and assessment methods. Finally, 14 patch test trials assessed by clinical scoring and evaporimetry emerged. Although the findings were generally positive, only few findings could be cross-checked from all the data, and vehicles seem to be as effective as BCs. Conclusion: Although this review highlights the poor quality and the lack of standardization of most studies, BCs seem to have protective effects against irritants. Further well-designed, adequately powered randomized controlled trials with clinical and biophysical assessments are required.

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“…A signifi cant deterioration was found in the control group. Therefore, the compliance to follow the skin protection regimen, especially the use of skin protection creams, should be enhanced [ 96 ].…”

Section: Moisturizers: Field and Patient Studiesmentioning

confidence: 99%

Moisturizers in the Prevention and Treatment of Hand Eczema

Lodén¹

2014

Textbook of Hand Eczema

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Effectiveness of skin protection measures in prevention of occupational hand eczema: results of a prospective randomized controlled trial over a follow-up period of 1 year

Abstract: The generally recommended skin protection regimen seems to provide effective prevention of occupational skin disease. Therefore, the compliance to follow the skin protection regimen, especially the use of skin protection, should be enhanced.

Cited by 87 publications

References 28 publications

Does Smoking Have a Significant Impact on Early Irritant Hand Dermatitis in Metal Workers?

Does Smoking Have a Significant Impact on Early Irritant Hand Dermatitis in Metal Workers?

Effectiveness of Barrier Creams against Irritant Contact Dermatitis

Moisturizers in the Prevention and Treatment of Hand Eczema

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