Background-It has been speculated that the conflicting results demonstrated across poststroke aphasia therapy studies might be related to differences in intensity of therapy provided across studies. The aim of this study is to investigate the relationship between intensity of aphasia therapy and aphasia recovery. Methods-A MEDLINE literature search was conducted to retrieve clinical trials investigating aphasia therapy after stroke.Changes in mean scores from each study were recorded. Intensity of therapy was recorded in terms of length of therapy, hours of therapy provided per week, and total hours of therapy provided. Pearson correlation was used to assess the relationship between changes in mean scores of outcome measures and intensity of therapy. Results-Studies that demonstrated a significant treatment effect provided 8.8 hours of therapy per week for 11.2 weeks versus the negative studies that only provided Ϸ2 hours per week for 22.9 weeks. On average, positive studies provided a total of 98.4 hours of therapy, whereas negative studies provided 43.6 hours of therapy. Total length of therapy time was found to be inversely correlated with hours of therapy provided per week (Pϭ0.003) and total hours of therapy provided (Pϭ0.001). define aphasia as "the loss of ability to communicate orally, through signs, or in writing, or the inability to understand such communications; the loss of language usage ability." Darley 2 noted that aphasia is generally described as an impairment of language resulting from focal brain damage to the language-dominant cerebral hemisphere. This serves to distinguish aphasia from the language and cognitivecommunication problems associated with non-languagedominant hemisphere damage, dementia, and traumatic brain injury. 3 However, defining aphasia as purely a disorder of language may oversimplify a complex clinical entity. Kertesz 4 clinically described aphasia as a "neurologically central disturbance of language characterized by paraphasias, word finding difficulty, and variably impaired comprehension, associated with disturbance of reading and writing, at times with dysarthria, non-verbal constructional and problemsolving difficulty and impairment of gesture."The most effective means of treating aphasia after stroke has yet to be determined, and studies investigating the efficacy of speech and language therapy (SLT) for patients See Editorial Comment, page 992 suffering aphasia after stroke have yielded conflicting results. One possible explanation for the observed heterogeneity of findings across studies is a difference in intensity of therapy. 5,6 We have noted that the failure to identify a consistent benefit might have been due to the low intensity of SLT applied in the negative studies, whereas higher intensities of therapy were present in positive studies. 7 A meta-analysis that included all patients suffering from aphasia, not just stroke patients, revealed that the more intensive the therapy, the greater the improvement. 8 The objective of the present study is to investiga...