Effectiveness of Synthetic Polymer-coated Peripherally Inserted Central Catheter in Patients With Advanced Cancer

Abstract

Background/Aim: A peripherally inserted central catheter (PICC) is recommended for the safe administration of anticancer agents. The effectiveness of synthetic polymercoated and non-coated PICCs was compared. Patients and Methods: Patients with advanced cancers who had indwelling PICCs were reviewed using their medical records. Three types of PICCs were compared in terms of complications and catheter failure. Results: A total of 90 patients were retrospectively analyzed, including 31 with Groshong PICCs, 30 with Argyle PICC kit, and 29 with Argyle PICC kit II. The incidence of catheter failure for Groshong PICC, Argyle PICC kit, and Argyle PICC kit II per 1,000 PICC days was 4.4614, 5.6617, and 0.8658, respectively. Catheter failure-free survival in the Argyle PICC kit II group was significantly better than that in the Argyle PICC kit group (p=0.0339). Conclusion: Argyle PICC kit II, a synthetic polymer-coated PICC, may render longer patency and prevention of catheter failure than non-coated PICCs.

Effects of Peripherally inserted Central Catheter (PICC) materials and designs on reduction of PICC‐related complications: A systematic review and meta‐analysis

“…A systematic review 17 suggested that antimicrobial PICCs may reduce CLABSI for the high‐risk population. Takezawa et al 26 showed that synthetic polymer‐coated PICC is safe and has less catheter complications. However, a prospective cohort study involving 52 hospitals showed that antimicrobial and antithrombogenic PICCs cannot reduce catheter complications, and proposed more attention to balance benefits against cost 16 .…”