Effectiveness of terbinafine in cutaneous alternariosis

Gf, Altomare; Capella, Giovanni Luigi; Boneschi, Vinicio; Viviani, M. A.

doi:10.1046/j.1365-2133.2000.03453.x

Cited by 25 publications

(12 citation statements)

References 3 publications

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“…S ir , We read with interest the recent report by Altomare et al . which described a patient with cutaneous alternariosis successfully treated with oral terfinafine 1 . We agree with the authors that cutaneous alternariosis is not exceptional (we have seen five cases in our department in 12 years), 2–5 especially in immunosuppressed patients.…”

supporting

confidence: 88%

Effectiveness of terbinafine in cutaneous alternariosis

Machet¹,

Machet

Vaillant³

2000

British Journal of Dermatology

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supporting

confidence: 88%

Effectiveness of terbinafine in cutaneous alternariosis

Machet¹,

Machet

Vaillant³

2000

British Journal of Dermatology

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“…Conversely, Alternaria species are resistant to griseofulvin and flucytosine. Oral and intralesional miconazole, 25 itraconazole, 23,26,27 fluconazole, terbinafine, 28 and amphotericin B 27 have been used with variable success. Some authors have postulated that itraconazole should be the treatment of choice, but the dose and duration of treatment are not fully established.…”

Section: Discussionmentioning

confidence: 99%

Cutaneous alternariosis in transplant recipients: Clinicopathologic review of 9 cases

Gilaberte

Bartralot²,

Torres

et al. 2005

Journal of the American Academy of Dermatology

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“…Organ transplantation is also a common risk factor (28,38,112,142,235,236,262,271,286,296,465,484,514,556,587,645,679,704,725). Apparently nosocomial cases have also been reported, with skin irritations from dressings or i.v.…”

Section: Phaeohyphomycosismentioning

confidence: 99%

Melanized Fungi in Human Disease

2010

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SUMMARY Melanized or dematiaceous fungi are associated with a wide variety of infectious syndromes. Many are soil organisms and are generally distributed worldwide, though certain species appear to have restricted geographic ranges. Though they are uncommon causes of disease, melanized fungi have been increasingly recognized as important pathogens, with most reports occurring in the past 20 years. The spectrum of diseases with which they are associated has also broadened and includes allergic disease, superficial and deep local infections, pneumonia, brain abscess, and disseminated infection. For some infections in immunocompetent individuals, such as allergic fungal sinusitis and brain abscess, they are among the most common etiologic fungi. Melanin is a likely virulence factor for these fungi. Diagnosis relies on careful microscopic and pathological examination, as well as clinical assessment of the patient, as these fungi are often considered contaminants. Therapy varies depending upon the clinical syndrome. Local infection may be cured with excision alone, while systemic disease is often refractory to therapy. Triazoles such as voriconazole, posaconazole, and itraconazole have the most consistent in vitro activity. Further studies are needed to better understand the pathogenesis and optimal treatment of these uncommon infections.

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Effectiveness of terbinafine in cutaneous alternariosis

Cited by 25 publications

References 3 publications

Effectiveness of terbinafine in cutaneous alternariosis

Effectiveness of terbinafine in cutaneous alternariosis

Cutaneous alternariosis in transplant recipients: Clinicopathologic review of 9 cases

Melanized Fungi in Human Disease

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