Effectiveness of the DHMAI monomer in the development of an antibacterial dental composite

Cherchali, Fatima Zohra; Mouzali, M.; Tommasino, Jean Bernard; Decoret, Dominique; Attik, Nina; Aboulleil, Hazem; Seux, Dominique; Grosgogeat, Brigitte

doi:10.1016/j.dental.2017.09.004

Cited by 33 publications

(34 citation statements)

References 41 publications

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“…Diverse research with different additives has been carried out to develop effective antibacterial composites. Numerous experiments have focused on resins containing polymerizable antibacterial additives, such as quaternary ammonium dimethacrylate (QADM) [ 25 ], 12-methacryloyloxydodecylpyridinium bromide (MDPB) [ 26 ], dimethylaminohexadecyl methacrylate (DMAHDM) [ 27 ], dimethyl-hexadecyl-methacryloxyethyl-ammonium iodide (DHMAI) [ 28 ], or dimethylaminododecyl and dimethylaminohexadecyl methacrylates [ 29 ]. Other organic materials including quaternary ammonium polyethylenimine (PEI) nanoparticles [ 30 ], chlorhexidine [ 31 , 32 ], triclosan [ 33 ], chitosan [ 34 ], and benzalkonium chloride and acrylic acid [ 35 ] were also tested with varying degrees of success.…”

Section: Introductionmentioning

confidence: 99%

Properties of Experimental Dental Composites Containing Antibacterial Silver-Releasing Filler

Stencel¹,

Kasperski

Pakieła

et al. 2018

Materials

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Secondary caries is one of the important issues related to using dental composite restorations. Effective prevention of cariogenic bacteria survival may reduce this problem. The aim of this study was to evaluate the antibacterial activity and physical properties of composite materials with silver sodium hydrogen zirconium phosphate (SSHZP). The antibacterial filler was introduced at concentrations of 1%, 4%, 7%, 10%, 13%, and 16% (w/w) into model composite material consisting of methacrylate monomers and silanized glass and silica fillers. The in vitro reduction in the number of viable cariogenic bacteria Streptococcus mutans ATCC 33535 colonies, Vickers microhardness, compressive strength, diametral tensile strength, flexural strength, flexural modulus, sorption, solubility, degree of conversion, and color stability were investigated. An increase in antimicrobial filler concentration resulted in a statistically significant reduction in bacteria. There were no statistically significant differences caused by the introduction of the filler in compressive strength, diametral tensile strength, flexural modulus, and solubility. Statistically significant changes in degree of conversion, flexural strength, hardness (decrease), solubility (increase), and in color were registered. A favorable combination of antibacterial properties and other properties was achieved at SSHZP concentrations from 4% to 13%. These composites exhibited properties similar to the control material and enhanced in vitro antimicrobial efficiency.

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Section: Introductionmentioning

confidence: 99%

Properties of Experimental Dental Composites Containing Antibacterial Silver-Releasing Filler

Stencel¹,

Kasperski

Pakieła

et al. 2018

Materials

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“…Diverse research with different additives has been carried out to develop effective antibacterial resin-based composites. Most of these additives are organic bactericides, such as: quaternary ammonium dimethacrylate (QADM) [21], dimethylaminohexadecyl methacrylates (DMAHDM) [22], dimethyl-hexadecylmethacryloxyethyl-ammonium iodide (DHMAI) [23], quaternary ammonium polyethylenimine (PEI) nanoparticles [24], chlorhexidine [25], triclosan [26] or chitosan [27]. Inorganic coatings have emerged as an alternative approach since they present several advantages compared to traditional organic agents, which include chemical stability, thermal resistance and protracted action, and they have not yet been associated with resistant organisms [28].…”

Section: Discussionmentioning

confidence: 99%

Prevention of Periodontitis by the Addition of a Bactericidal Particulate Glass/Glass-Ceramic to a Dental Resin: A Pilot Study in Dogs

et al. 2018

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The aim of the study is to evaluate, in a ligature-induced periodontitis model, the efficacy of a commercially available dental resin containing different antimicrobial glass/glass-ceramic additions (0–26 wt.%). It has been proved that a 26 wt.% glass addition to a conventional dental resin matrix does not alter neither its workability nor its adhesion to the surface of teeth; however, it does confer notable antimicrobial properties when tested in vitro. Moreover, in vivo tests in Beagle dogs demonstrated the prevention of bone loss in ligature-induced plaque accumulation around teeth. Particularly, the glass-ceramic filler resin composite has shown excellent antimicrobial control since it displays the same bone loss as that of the negative control. The results obtained in the present investigation have shown that a conventional dental resin containing a fraction of glass/glass-ceramic (≥26 wt.%) can prevent periodontitis, which is considered to be a most serious dental disease.

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“…This result was expressed with MPC at 3 wt.% and with QAM at 1.5 wt.%. Cherchali et al [49], with a similar aim, explored the synergism of MPC with QAM and dimethyl-hexadecyl-methacryloxyethyl- Intervention in the material properties can be made to draw an effect at various levels such that it can prevent adhesion and maturation or denatures and kills the constituent microorganism of the biofilm. Each intervention can be objectively analyzed by the corresponding measurands.…”

Section: Restorative Materialsmentioning

confidence: 99%

Bio-Interactive Zwitterionic Dental Biomaterials for Improving Biofilm Resistance: Characteristics and Applications

Mangal

Kwon

Choi

2020

IJMS

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Biofilms are formed on surfaces inside the oral cavity covered by the acquired pellicle and develop into a complex, dynamic, microbial environment. Oral biofilm is a causative factor of dental and periodontal diseases. Accordingly, novel materials that can resist biofilm formation have attracted significant attention. Zwitterionic polymers (ZPs) have unique features that resist protein adhesion and prevent biofilm formation while maintaining biocompatibility. Recent literature has reflected a rapid increase in the application of ZPs as coatings and additives with promising outcomes. In this review, we briefly introduce ZPs and their mechanism of antifouling action, properties of human oral biofilms, and present trends in anti-biofouling, zwitterionic, dental materials. Furthermore, we highlight the existing challenges in the standardization of biofilm research and the future of antifouling, zwitterated, dental materials.

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Effectiveness of the DHMAI monomer in the development of an antibacterial dental composite

Cited by 33 publications

References 41 publications

Properties of Experimental Dental Composites Containing Antibacterial Silver-Releasing Filler

Properties of Experimental Dental Composites Containing Antibacterial Silver-Releasing Filler

Prevention of Periodontitis by the Addition of a Bactericidal Particulate Glass/Glass-Ceramic to a Dental Resin: A Pilot Study in Dogs

Bio-Interactive Zwitterionic Dental Biomaterials for Improving Biofilm Resistance: Characteristics and Applications

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