2018
DOI: 10.1016/s0140-6736(18)30295-2
|View full text |Cite|
|
Sign up to set email alerts
|

Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

21
770
14
25

Year Published

2018
2018
2024
2024

Publication Types

Select...
9

Relationship

3
6

Authors

Journals

citations
Cited by 888 publications
(830 citation statements)
references
References 43 publications
21
770
14
25
Order By: Relevance
“…Our observed antidepressant effect (70% response rate and 40% remission rate) compares favorably to other investigations (with typical response rates ranging from 50 to 60%, and typical remission rates ranging from 30% to 40%) [Blumberger et al, ; Dunner et al, ; O'Reardon et al, ]. There were no self‐identified improvements in ASD core symptoms; however, informants identified sustained improvements in hyperactivity and irritability as well as potential improvements in ritualistic, sameness, and restricted behaviors.…”
Section: Discussionsupporting
confidence: 76%
See 1 more Smart Citation
“…Our observed antidepressant effect (70% response rate and 40% remission rate) compares favorably to other investigations (with typical response rates ranging from 50 to 60%, and typical remission rates ranging from 30% to 40%) [Blumberger et al, ; Dunner et al, ; O'Reardon et al, ]. There were no self‐identified improvements in ASD core symptoms; however, informants identified sustained improvements in hyperactivity and irritability as well as potential improvements in ritualistic, sameness, and restricted behaviors.…”
Section: Discussionsupporting
confidence: 76%
“…Two participants (15%), withdrew from the trial due to irritability ( N = 1), or treatment emergent anxiety ( N = 1). This attrition rate is somewhat higher than depression trials in neurotypical adults with MDD [Blumberger et al, ; George et al, ; O'Reardon et al, ], which range from 5 to 8%. The most serious risk associated with the use of rTMS is seizure, which occurs at a low rate (estimated to be <0.1% under the FDA‐cleared protocol [O'Reardon et al, ]).…”
Section: Discussionmentioning
confidence: 85%
“…Furthermore, a recent clinical trial comparing the antidepressant efficacy between conventional 10 Hz rTMS and iTBS found similar antidepressant effects in approximately 200 patients in each group(Blumberger et al, 2018), suggesting the possibility of iTBS as a treatment option. A recent meta-analysis investigating the efficacy of TBS in major depression demonstrated a favourable clinical response to treatment, particularly with intervention involving iTBS (Berlim, McGirr, Rodrigues Dos Santos, Tremblay, & Martins, 2017).…”
mentioning
confidence: 95%
“…Potentiation of positive synaptic engrams would appear superior to enhancement of a patients usual depressive ruminations occurring while the patient is “at rest” or undirected. New data suggest theta burst rTMS stimulation works as well as the regular stimulation, and only requires 5 minutes/session rather than the usual 25 minutes …”
Section: Somatic Treatmentsmentioning
confidence: 99%