Effectiveness of topical use of Lietofix® in wound healing after pilonidalis sinus excision: a multicenter study by the Italian Society of Colorectal Surgery (SICCR)

Giannini, Ivana; Andreoli, R.; Bianchi, Francesco Paolo; Cavallaro, V; Corno, F; Geccherle, Andrea; Ghiglione, F; Legnaro, A.; Losacco, L; Marola, Silvia; Orlandi, Simone; Pecorella, G; Pennisi, Damiano; Perinotti, Roberto; Poli, Federica; Pozzo, M; Pulzato, Luca; Schembari, Elena; Tafuri, Silvio; Tegon, G.; Tricomi, N.; Velci, Luigi; Vittadello, Fabrizio; Santoro, G. A.

doi:10.1007/s10151-019-01950-x

Cited by 4 publications

(3 citation statements)

References 5 publications

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“…Open healing, aside from causing patient discomfort, may require frequent painful dressings, and close clinical observation. Dressings should provide an optimal environment for wound healing, and the so called “advanced dressings” do this by simple physical or chemical means, typically by controlling moisture levels, with the aim of optimizing wound cleansing and re-epithelization (for example, calcium alginate, film, foam, hydrocolloid, and hydrogel dressings) [ 79 – 82 ].…”

Section: Methodsmentioning

confidence: 99%

Consensus statement of the Italian society of colorectal surgery (SICCR): management and treatment of pilonidal disease

et al. 2021

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Pilonidal disease (PD) is a relatively common, benign but challenging condition of the natal cleft. This consensus statement was drawn up by a panel of surgeons, identified by the Italian Society of Colorectal Surgery (SICCR) as having a “special interest” in PD, with the aim of recommending the best therapeutic options according to currently available scientific evidence. A three-step modified-Delphi process was adopted, implying: (1) choice of the panelists; (2) development of a discussion outline and of target issues; and (3) a detailed systematic review of the current literature. The agreement/disagreement level was scored on a five-point Likert scale as follows: “A + : strongly agree; A–: agree; N: unsure/no opinion; D–: disagree; D + : strongly disagree. Each panelist contributed to the production of this manuscript, and the final recommendations were reviewed by the Clinical Practice Guidelines Committee.

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Section: Methodsmentioning

confidence: 99%

Consensus statement of the Italian society of colorectal surgery (SICCR): management and treatment of pilonidal disease

et al. 2021

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“…A recent trial by Sadati et al, 15 confirmed this clinical benefit. Moreover, in a multicenter RCT, 31 the local use of an alginate‐based cream expedited the rate of re‐epithelialization and complete wound healing. Although our experimental group displayed a shorter healing time, compared to conventional dressings, statistical significance was not confirmed.…”

Section: Discussionmentioning

confidence: 99%

The role of alginate dressings in wound healing and quality of life after pilonidal sinus resection: A randomised controlled trial

Mamaloudis

Perivoliotis

Zlatanos

et al. 2022

International Wound Journal

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In this trial, we evaluated the role of alginate dressings in the secondary intention wound healing and quality of life (QoL) after pilonidal sinus resection.The study was designed as a prospective randomised controlled trial (RCT). In the experimental group, alginate dressings with silver and high-G cellulose were introduced after elective pilonidal cyst excision, whereas in the control group, simple gauges were used. The primary end point was the difference in terms of the wound healing period. Blinding existed at the level of the investigator. Overall, 65 patients were included during the study period. Wound healing duration was comparable between the two groups (P = .381). No difference in postoperative pain scores or recovery outcomes was found. The experimental group was associated with reduced wound secretions at specific time end points. Similarly, no effect was identified, on overall Wound-QoL or SF-36 scores. Alginate dressings do not accelerate wound healing or improve QoL. Due to suboptimal sample size and several study limitations, further RCTs are required to confirm our findings.

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“… 5 Some studies have used advanced dressings to provide an optimal environment for wound healing, typically by optimizing wound cleansing and re-epithelization. 6 …”

Section: Introductionmentioning

confidence: 99%

Platelet-rich plasma for pilonidal disease: a systematic review

Zhuang,

Feng

2023

J Int Med Res

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Objective To examine the use of platelet-rich plasma (PRP) for treatment of pilonidal disease (PD) and thus provide a reference for clinical application. Methods A systematic review of PubMed and the Cochrane Library was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. We considered all studies that reported the use of PRP for treatment of PD. Extracted data included the first author’s name, year of publication, study type, number of included patients, inclusion and exclusion criteria, interventions, anesthesia, application of PRP (source, preparation, dose, and operation), antibiotics, follow-up time, therapeutic outcomes, and adverse events. Results In total, eight randomized controlled trials and one prospective cohort study involving 809 patients were included. PRP reduced pain, accelerated healing, and reduced adverse events. The application of combined minimally invasive surgery achieved better results. However, overfilling of the wound with PRP in minimally invasive surgeries was shown to potentially increase the risk of adverse events. Conclusion PRP can be used as an adjuvant treatment in PD surgery to improve the therapeutic effect and reduce adverse events. The optimal combination of PRP and various factors is an important direction of future research. INPLASY registration number: INPLASY2023100070.

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Effectiveness of topical use of Lietofix® in wound healing after pilonidalis sinus excision: a multicenter study by the Italian Society of Colorectal Surgery (SICCR)

Cited by 4 publications

References 5 publications

Consensus statement of the Italian society of colorectal surgery (SICCR): management and treatment of pilonidal disease

Consensus statement of the Italian society of colorectal surgery (SICCR): management and treatment of pilonidal disease

The role of alginate dressings in wound healing and quality of life after pilonidal sinus resection: A randomised controlled trial

Platelet-rich plasma for pilonidal disease: a systematic review

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