Effectiveness of Zinc Supplementation in Treating Dysmenorrhea

Farrah, Aurora Marezkha; Halim, Binarwan; Kaban, Yostoto B

doi:10.15562/bmj.v6i1.380

Cited by 6 publications

(9 citation statements)

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“…Sundari LR 23 used even a lower dose of Zinc 30mg capsules in 16 medical students who had primary dysmenorrhea, only for four days before menstruation in one cycle only and showed a significant improvement not only in pain severity but also a significant reduction in PGF2 alpha levels. Farah AM 24 observed a gradual improvement in pain severity after 30mg ZnSO4 for 3 consecutive cycles. There is still no consensus on the dose and duration of treatment.…”

Section: Discussionmentioning

confidence: 95%

Perception of undergraduate medical students regarding civic responsibility through service learning by visiting persons with different abilities

Naseem¹

2022

JRMC

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Objectives: Addressing various attitudes of students, can be a challenging task for educationists, so it is generally embedded in the hidden curriculum in most Medical Institutes. The purpose of this study was to build up civic duty among undergraduates, rooted in their learning objectives of the curriculum through a visit to the school of children with different abilities (CFSPF). Materials and Methods: In year 4, students of Shifa College of Medicine during the clerkship of Community Medicine, were taken on a field visit which is part of the curriculum. CFSP is privately run by an NGO, it has 45 enrolled individuals with different mental and physical abilities. The medical students visited CFSPF in small groups for 8 months (Sep 2019 to April 2020) where they interacted with the individuals with special needs in their environment. Students were able to practice empathy through the general physical examination and other entertaining activities. In this qualitative study, this strategy was assessed by exploring the medical student’s perceptions. Results: Focus Group discussions were conducted with the medical students and themes identified were: interaction with children having different abilities, being thankful to the Almighty, philanthropy, learning to empathize, the feeling of including them in our society, selfless smile, the contribution of services, and developing various attributes. Conclusion: Students found the visit to a school for children with different abilities useful. The interaction in a different environment has revealed opportunities for a wider scope of learning. Keywords: Civic responsibility, Empathy, Persons with different abilities, Service learning.

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Section: Discussionmentioning

confidence: 95%

Perception of undergraduate medical students regarding civic responsibility through service learning by visiting persons with different abilities

Naseem¹

2022

JRMC

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“…Zn supplementation has been reported to prevent uterine spasms and cramps, inducing a reduction in prostaglandin synthesis by reducing cyclooxygenase-2 (COX-2) activity and an improvement in endometrial tissue microcirculation (40)(41)(42). The administration of Zinc, at concentrations between 20 and 126 mg/day for 3-6 days before and after menstruation, reduces pain in the first menstrual cycle after the first intake, although the reduction in pain was greater in subsequent cycles (42)(43)(44)(45).…”

Section: Discussionmentioning

confidence: 99%

Study of the recommended dosage of the N-Acetyl Cysteine, Alpha Lipoic Acid, Bromelain and Zinc preparation as a treatment for dysmenorrhea

Estrada¹,

Carmona

2022

Preprint

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Dysmenorrhea, defined as pain during menstruation, is the most common gynecological condition, affecting a large percentage of women with varying degrees of pain. In recent years, the management of dysmenorrhea has become increasingly important because of the emotional, health and economic burden it entails and because of the need for new studies and research for effective treatments to alleviate its symptoms. The most common treatments for dysmenorrhea are NSAIDs or oral contraceptives, although gynecologists also recommend the preparation composed of N-acetyl cysteine (NAC), alpha lipoic acid (LA), bromelain (Br) and Zinc (Zn), (NAC/LA/Br/Zn) due to its anti-inflammatory and anti-oxidative properties and efficacy in reducing pain. However, there is no data on what dosage of the preparation should be recommended for patients with dysmenorrhea. Therefore, the aim of this study is to determine how the NAC/LA/Br/Zn preparation is recommended for the treatment of dysmenorrhea in daily clinical practice and what specialists base their decision on. A survey was conducted among gynecologists with extensive experience recommending the preparation, with a participation rate of 97% (N=73). The most frequently recommended regimen is to begin with continuous administration for 90 days with 10-day breaks (69%) or without breaks (31%). Specialists recommend the preparation for any type of pain and may recommend discontinuous administration (in the days around menstruation) when the pain is moderate or mild. In patients with primary dysmenorrhea with mild pain, the most recommended approach is discontinuous therapy in the days around menstruation (50.7%) followed by continuous administration for 90 days with 10-day breaks (24.7%). When pain is moderate or severe, the most recommended approach is 90-day continuous therapy with 10-day breaks (47.9% and 71.2%, respectively). In the case of secondary dysmenorrhea, the most recommended approach is 90-day continuous therapy with 10-day breaks for any degree of pain (41.1%, 57.5% and 76.7% for mild, moderate and severe pain, respectively). Most gynecologists (79%) adapt the regimen after clinical assessment of the degree of pain towards discontinuous administration patterns, on the days around menstruation. Most of the specialists consulted do not modify the recommended regimen if the patient is being treated with other drugs such as NSAIDs, hormonal contraception or a combination of progestogens (78%, 59% and 58%, respectively). The preparation is recommended in conjunction with hygienic-dietary measures without modification of the dosage (90%). This is the first study that addresses how specialists recommend the NAC/LA/Br/Zn preparation to patients with dysmenorrhea. The most common regimen for dysmenorrhea is to start treatment with continuous administration of the preparation for 90 days with 10 days of break, continuing the regimen or adapting it according to the degree of pain reported by the patient during treatment.

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“…Zink memiliki kandungan antioksidan dan anti inflamasi yang berguna menghambat metabolisme prostaglandin. Asupan zat ini akan membantu mengurangi kram saat menstruasi (16).…”

Section: Perbedaan Asupan Zink Pada Remaja Putri Atlet Dismenorea Dan Tidak Dismenoreunclassified

Analisis perbedaan asupan kalsium, magnesium, zink, dan aktivitas fisik berdasarkan kejadian dismenorea pada remaja putri atlet di SMA Negeri Ragunan

Wahyuni

Fasya

Novianti

2021

ilgi

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Latar Belakang: Dismenorea adalah nyeri yang terjadi terutama di perut bagian bawah yang dapat menyebar hingga ke punggung bagian bawah, pinggang, panggul, paha atas, hingga betis. Faktor yang memengaruhi dismenorea antara lain defisiensi asupan zat gizi dan aktivitas fisik. Asupan zat gizi yang berpengaruh pada dismenorea diantaranya adalah asupan kalsium, magnesium dan zink. Tujuan: Untuk menganalisis perbedaan asupan kalsium, magnesium, zink, dan aktivitas fisik berdasarkan kejadian dismenorea di SMA Negeri Ragunan (Khusus Olahragawan). Metode: Penelitian ini merupakan penelitian kuantitatif melalui pendekatan observasional analitik dengan desain case control. Responden dalam penelitian ini terbagi menjadi dua kelompok yaitu kelompok dismenorea dan tidak dismenore, dengan masing-masing kelompok berjumlah 32 orang. Pengambilan sampel dilakukan dengan teknik purposive sampling. Data yang dikumpulkan meliputi data karakteristik responden, data asupat zat gizi mikro yang dikumpulkan menggunakan Semi Quantitative Food Frequency Questionnaire. Data aktivitas fisik dikumpulkan menggunakan kuesioner Physical Activity Level, data kram perut saat menstruasi dikumpulkan menggunakan Numerical Rating Scale. Analisis bivariat menggunakan uji statistik Independent t-Test dan Mann Whitney. Hasil: Ada perbedaan yang signifikan pada variabel asupan kalsium, asupan magnesium, dan aktivitas fisik (p<0,05). Tidak ada perbedaan yang signifikan pada variabel asupan zink (p>0,05). Kesimpulan: Ada perbedaan asupan kalsium, asupan magnesium, dan aktivitas fisik pada remaja putri atlet yang mengalami dismenorea dan tidak mengalami dismenorea. Tidak ada perbedaan asupan zink pada remaja putri yang mengalami dismenorea dan tidak mengalami dismenorea.

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Effectiveness of Zinc Supplementation in Treating Dysmenorrhea

Cited by 6 publications

References 0 publications

Perception of undergraduate medical students regarding civic responsibility through service learning by visiting persons with different abilities

Perception of undergraduate medical students regarding civic responsibility through service learning by visiting persons with different abilities

Study of the recommended dosage of the N-Acetyl Cysteine, Alpha Lipoic Acid, Bromelain and Zinc preparation as a treatment for dysmenorrhea

Analisis perbedaan asupan kalsium, magnesium, zink, dan aktivitas fisik berdasarkan kejadian dismenorea pada remaja putri atlet di SMA Negeri Ragunan

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