One of the main benefits of Building Information Modelling is the capability of improving the decision-making process thanks performing what-if tests on digital twins of the building to be realized. Pairing BIM models to Building Energy Models allows designers to determine in advance the energy consumption of the building, improving sustainability of the construction. The challenge is to consider as many elements involved in the energy balance as possible and shuffling their parameters within a certain range. In this work, the automatic creation of a relevant set of design options to be analyzed for searching the optimum has been carried out. Firstly, the usual workflow that would be applied manually has been automatically followed by running scripts and codes, depending just on the initial setup given by the user. Although the procedure is very resource consuming, the main advancement relies in the reduction of the manual intervention and the possibility of creating large datasets of design options, avoiding gross errors. Secondly, Artificial Neural Networks and Transfer Learning techniques are applied to speed up the process of dataset creation. With such approach, the same dataset has been created, with about 30% of initial data and without significant loss of accuracy.