Effectivity of Optical Coherence Tomography for the Diagnosis of Urothelial Bladder Cancer

Sachs, Murray B.; Daniltchenko, Dmitri; Heinau, Marc; Koenig, Frank; Loening, Stefan A.; Аль-Шукри, С Х; Schnorr, Dietmar

doi:10.1016/s1569-9056(08)60265-1

Cited by 1 publication

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“…Sachs et al [43] and Lerner et al [8] published comparable results in recognition of cancer of the bladder, including invasive exophytic forms. Our study demonstrated diagnostic efficacy of CP OCT in detecting early malignization in flat suspicious zones.…”

Section: Discussionmentioning

confidence: 85%

“…We compared results of the current research (Table 4, column 1) and two statistical OCT studies in urology performed by Sachs et al [43] and Lerner et al [8] in 2008 (Table 4, columns 4-7). The compared studies differed by a number of parameters.…”

Section: Discussionmentioning

confidence: 99%

“…The compared studies differed by a number of parameters. The main difference was the OCT device: our team used a CP OCT device, whereas Sachs et al [43] and Lerner et al [8] employed traditional optical coherence tomography. The quantity and groups of patients were different too.…”

Section: Discussionmentioning

confidence: 99%

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Cross‐polarization optical coherence tomography for early bladder‐cancer detection: statistical study

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et al. 2010

Journal of Biophotonics

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The capabilities of cross-polarization optical coherence tomography (CP OCT) for early bladder-cancer detection are assessed in statistical study and compared with the traditional OCT. Unlike the traditional OCT that demonstrates images only in copolarization, CP OCT acquires images in cross-polarization and copolarization simultaneously. 116 patients with localized flat suspicious lesions in the bladder were enrolled, 360 CP OCT images were obtained and analyzed. CP OCT demonstrated sensitivity 93.7% (vs. 81.2%, <0.0001), specificity 84% (vs. 70.0%, <0.001) and accuracy 85.3% (vs. 71.5%, <0.001) in detecting flat malignant bladder lesions, which is significantly better than with the traditional OCT. Higher diagnostic efficacy of CP OCT in detecting early bladder cancer is associated with the ability to detect changes in epithelium and connective tissues.

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Section: Discussionmentioning

confidence: 85%

Section: Discussionmentioning

confidence: 99%