Effects and safety of fire needle adjuvant chemical peels therapy in acne vulgaris: a systematic review and meta-analysis

Zhang, Jianfeng; Lin, Peng; Guo, Chenqi; Ma, Cong; Liu, Yiting; Wang, Yingdong; Zhang, Yu

doi:10.1080/09546634.2023.2240455

Journal of Dermatological Treatment

2023

DOI: 10.1080/09546634.2023.2240455

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Effects and safety of fire needle adjuvant chemical peels therapy in acne vulgaris: a systematic review and meta-analysis

Jianfeng Zhang,

Peng Lin,

Chenqi Guo

et al.

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2024

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Cited by 3 publications

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Fire needle pretreatment with 5-aminolevulinic acid photodynamic therapy combined with low-dose isotretinoin in the treatment of severe refractory nodulocystic acne

Du,

Cao,

Wei

et al. 2024

Photodiagnosis and Photodynamic Therapy

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Fire needle pretreatment with 5-aminolevulinic acid photodynamic therapy combined with low-dose isotretinoin in the treatment of severe refractory nodulocystic acne

Du,

Cao,

Wei

et al. 2024

Photodiagnosis and Photodynamic Therapy

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Efficacy of fire needle combined with 308 nm excimer laser therapy for vitiligo: A systematic review and meta‐analysis of randomized controlled trials

Guo,

Gu,

Zhang

et al. 2024

J of Cosmetic Dermatology

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IntroductionVitiligo is a common depigmenting skin disorder. This work is performed to systematically evaluate the efficacy and safety of fire needles combined with 308 nm excimer laser therapy in treating vitiligo.MethodsWe searched the PubMed, EMBASE, Cochrane Library, Web of Science, CNKI, Wanfang, and VIP databases. Randomized controlled trials (RCTs) on fire needles combined with 308 nm excimer laser therapy with 308 nm excimer laser therapy alone for vitiligo were included. The Cochrane Collaborative Network Tool was used to assess the risk of bias. Statistical analysis was completed using RevMan5.3 software and Stata 15.0 software. The GRADE system was used to evaluate the quality of evidence for outcomes.ResultsIn this study, 10 RCTs and 1333 patients were included. The results showed that compared with 308 nm excimer laser therapy alone, fire needle combined with 308 nm excimer laser therapy is more effective in improving clinical effective rate (RR = 1.36, 95% CI [1.24, 1.50], p < 0.00001), serum CD4+ level (MD = 3.12, 95% CI [2.50, 3.74], p < 0.00001), CD4+/CD8+ ratio (MD = 0.24, 95% CI [0.09, 0.39], p = 0.001), and quality of life measured by the Dermatology Life Quality Index (DLQI) (MD = 3.76, 95% CI [3.33, 4.19], p < 0.00001), and reducing the Vitiligo Area Score Index (VASI) (MD = −5.47, 95% CI [−6.56, −4.37], p < 0.00001). The reported adverse events, including redness, swelling, pain, blisters, and itching, were controllable, and all these events were well tolerated.ConclusionThe current evidence indicates that fire needle combined with 308 nm excimer laser therapy is effective and safe for vitiligo. However, owing to the suboptimal quality of the included studies, more high‐quality and large‐scale RCTs are needed for comprehensive analysis and further validation.

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Fire needle therapy for the treatment of cancer pain: a protocol for the systematic review and meta-analysis

Zhang,

Ren,

et al. 2024

Front. Neurol.

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BackgroundCancer patients frequently suffer pain as one of their symptoms. It includes acute and chronic pain and is one of the most feared symptoms for patients. About one-third of adults actively undergoing cancer treatment suffer from pain related to their condition. Cancer pain control remains suboptimal due to a lack of assessment, knowledge, and access. Fire needle therapy, a traditional Chinese medicine, offers a potentially beneficial addition to current pain management approaches. This protocol outlines a systematic review and meta-analysis to compile evidence and examine the pain-relieving effects and safety of fire needle therapy for cancer patients.Methods and analysisWe will systematically search China National Knowledge Infrastructure (CNKI), Wanfang Database, China Biology Medicine disc (CBM), China Science and Technology Journal Database (CSTJ or VIP), PubMed, Web of Science, Embase, Cochrane Central Registry of Controlled Trials (CENTRAL), Chinese Clinical Trial Registry (Chictr), Opengrey, Worldcat, and Scopus from inception through July 2023. Random control trials (RCTs) include all types of cancer patients (age ≥ 18 years) complaining of pain. The primary outcome will be changes in pain intensity measured by Visual Analogue Scale (VAS), Numerical Rating Scale (NRS), Neuropathic Pain Scale (NPS), or Brief Pain Inventory (BPI). Secondary outcomes include quality of life (EORTC QLQ-C30 and GCQ), performance status (KPS), times of burst pain, treatment response rate, the dose reduction of analgesic drugs, and side effects rates. Utilizing the Cochrane risk bias measurement tool: Risk of Bias 2 (RoB 2), the trials’ quality will be evaluated, and meta-analysis will be performed using RevMan software (version 5.4).DiscussionThis systematic review will be the first comprehensive review of the literature to provide a meta-analysis of fire needle therapy for cancer pain, including only Random control trials (RCTs). For the sake of transparency and to avoid future duplication, the publication of this protocol offers a clear illustration of the procedures utilized in this evaluation. The results of our future studies may provide a new approach and theoretical basis for the treatment of cancer pain by medical oncology professionals.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42023418609.

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Effects and safety of fire needle adjuvant chemical peels therapy in acne vulgaris: a systematic review and meta-analysis

Cited by 3 publications

References 28 publications

Fire needle pretreatment with 5-aminolevulinic acid photodynamic therapy combined with low-dose isotretinoin in the treatment of severe refractory nodulocystic acne

Fire needle pretreatment with 5-aminolevulinic acid photodynamic therapy combined with low-dose isotretinoin in the treatment of severe refractory nodulocystic acne

Efficacy of fire needle combined with 308 nm excimer laser therapy for vitiligo: A systematic review and meta‐analysis of randomized controlled trials

Fire needle therapy for the treatment of cancer pain: a protocol for the systematic review and meta-analysis

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