2019
DOI: 10.4172/neuropsychiatry.1000560
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Effects and Therapeutic Use of TMS in Psychiatric Disorders: An Evidence-Based Review

Abstract: ObjectiveRecently we found that chronic immobilization stress (CIS) induced low levels of glutamate (Glu) and glutamine (Gln) and hypoactive glutamatergic signaling in the mouse prefrontal cortex (PFC), which was closely related with Glu-Gln cycle. Moreover, Gln-supplemented diet ameliorated CISinduced deleterious changes. In the present study, therefore, we investigated the effects of CIS and Gln supplementation on Glu-Gln cycle-related proteins to understand underlying mechanisms. MethodsUsing CIS-induced de… Show more

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“…Encouraging results have been reported in the treatment of various neurological disorders, including Parkinson's disease, stroke, and chronic pain, with promising outcomes (Kim et al., 2010; Shen et al., 2017). Furthermore, rTMS has demonstrated potential in the treatment of psychiatric disorders, such as major depressive disorder (MDD), obsessive‐compulsive disorder (OCD), PTSD, and schizophrenia (Berlim et al., 2013; Camacho‐Conde et al., 2023; Escribano et al., 2019; Freitas et al., 2009; Yan et al., 2017). These findings highlight the non‐invasive, versatile, and safe nature of rTMS as a treatment modality, holding great promise for a wide range of neurological and psychiatric conditions.…”
Section: Introductionmentioning
confidence: 99%
“…Encouraging results have been reported in the treatment of various neurological disorders, including Parkinson's disease, stroke, and chronic pain, with promising outcomes (Kim et al., 2010; Shen et al., 2017). Furthermore, rTMS has demonstrated potential in the treatment of psychiatric disorders, such as major depressive disorder (MDD), obsessive‐compulsive disorder (OCD), PTSD, and schizophrenia (Berlim et al., 2013; Camacho‐Conde et al., 2023; Escribano et al., 2019; Freitas et al., 2009; Yan et al., 2017). These findings highlight the non‐invasive, versatile, and safe nature of rTMS as a treatment modality, holding great promise for a wide range of neurological and psychiatric conditions.…”
Section: Introductionmentioning
confidence: 99%