Effects of 2,2-Dichlorovinyl Dimethyl Phosphate (DDVP) on Hsp70 Gene Expression in Rainbow Trout

Erdoğan, Orhan; Atamanalp, Muhammed; Şi̇şman, Turgay; Aksakal, Ecrument; Alak, Gonca

doi:10.46989/001c.20532

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…Dichlorvos (2, 2 dichlorovinyl dimethyl phosphate; DDVP), is a household and agricultural pesticide used for the protection of grains and stored products, traded under names such as Sniper, Nuvan and Ota-piapia [5]. It's also used to treat external parasitic infections in livestock, farmed fish and domestic animals [6]. Dichlorvos is reported to cause toxicity of brain [7], pancreas [8], kidney and spleen [9], the reproductive system [10] and immune system [11].…”

Section: Introductionmentioning

confidence: 99%

Mitigating Effects of Zingiber Officinale Against Reproductive Toxicity Induced by Dichlorovos in Male Rats

Joshi,

Sharma,

Joshi

2017

Int J Pharm Pharm Sci

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Objective: Aim of this study was to evaluate the effect of Z. officinalein mitigating oxidative damage and reproductive toxicity in the testis, induced by chronic dichlorovos administration in male Wistar rats.Methods: Twenty four adult male Wistar rats were divided into 4 groups of 6 rats in each group. Group I received olive oil (1 ml/ kg bwt/day) and served as control group, while Group II was administered dichlorovos (20 mg/kg bwt/day) and Group III & IV received a combination of dichlorovos (20 mg/kg bwt) andZingiber officinale (ginger) extract (100 & 200 mg/kg bwt) for 45 days. At the end of the treatment period, the rats were sacrificed.Results: The weight of the reproductive organs and serum FSH, LH and testosterone levels were assayed. Lipid peroxidation (LPO) (indexed by MDA) and antioxidants enzymes GSH, SOD, CAT were also analysed. Dichlorovos treatment decreased the weight of testis, epididymis, prostate and seminal vesicle as well as the serumlevels of FSH, LH and testosterone. There was a decrease in the activities of GSH, SOD and CAT as well as an increase in MDA concentration.Conclusion: Co-administration of aqueous extract ofZingiber officinalewith dichlorovos showed protective effect and increases the reproductive organs weight and enhancesserum hormones level along with increased antioxidants activities and reduced lipid peroxidation. This indicates that Zingiber officinale mitigates reproductive toxicity and oxidative damage induced by dichlorovos exposure due to its antioxidant activity in the testes.

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Section: Introductionmentioning

confidence: 99%

Mitigating Effects of Zingiber Officinale Against Reproductive Toxicity Induced by Dichlorovos in Male Rats

Joshi,

Sharma,

Joshi

2017

Int J Pharm Pharm Sci

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The impact of climate change on aquatic risk from agricultural pesticides in the US

Koleva

Schneider

2010

International Journal of Environmental Studies

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We investigate how climate change may affect the acute and chronic toxicity risk to aquatic species from agricultural pesticides in 32 States of the US. We combine climate change projections from the Canadian and Hadley climate model, statistically estimated relationships between pesticide applications and climate and weather variables, and the environmental risk indicator REXTOX developed by the OECD. On average, we find that climate change is likely to increase the toxicity risk to aquatic species by 47% because of increased applications of agricultural pesticides. Daphnia and fish are more affected than algae. Across eight broad crop groups, pesticides used on pome and stone fruits and on fruiting vegetables contribute the most to aquatic risk. Within the 32 US States examined, more than 90% of the pesticide pollution impacts induced by climate change on the aquatic environment are caused by only 13 States near to the coast.

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Alterations of HSP70 gene expression in rainbow trout (Oncorhyncus mykiss) exposed to deltamethrin

Atamanalp¹,

Erdoğan²

2010

Turkish Journal of Veterinary & Animal Sciences

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Effects of 2,2-Dichlorovinyl Dimethyl Phosphate (DDVP) on Hsp70 Gene Expression in Rainbow Trout

Cited by 3 publications

References 9 publications

Mitigating Effects of Zingiber Officinale Against Reproductive Toxicity Induced by Dichlorovos in Male Rats

Mitigating Effects of Zingiber Officinale Against Reproductive Toxicity Induced by Dichlorovos in Male Rats

The impact of climate change on aquatic risk from agricultural pesticides in the US

Alterations of HSP70 gene expression in rainbow trout (Oncorhyncus mykiss) exposed to deltamethrin

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