Effects of 6- and 7-hydroxy metabolites of 3β,17β-dihydroxy-5α-androstane on gonadotrophin and prolactin secretion and on sex accessories weight of male rats

The identification and simultaneous quantification of 7-hydroxylated metabolites of pregnenolone, dehydroepiandrosterone, 3β,17β-androstenediol, and testosterone in human serum using gas chromatography–mass spectrometry

“…On the other hand, a deactivation role for 7-hydroxylation of sex hormones as well as for brain neurosteroids is possible [16][17][18][19]. Neither androgenic nor estrogenic effects have been described for 7-hydroxylated metabolites of sex hormones [20,21].…”