Effects of a 12-Week Multifaceted Wearable-Based Program for People With Knee Osteoarthritis: Randomized Controlled Trial

Abstract

<jats:sec> <jats:title>Background</jats:title> <jats:p>Current guidelines emphasize an active lifestyle in the management of knee osteoarthritis (OA), but up to 90% of patients with OA are inactive. In a previous study, we demonstrated that an 8-week physiotherapist (PT)-led counseling intervention, with the use of a Fitbit, improved step count and quality of life in patients with knee OA, compared with a control.</jats:p> </jats:sec> <jats:sec> <jats:title>Objective</jats:title> <jats:p>This study aimed to examine the effect of a 12-week, multifaceted wearable-based program on physical activity and patient outcomes in patients with knee OA.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>This was a randomized controlled trial with a delay-control design. The immediate group (IG) received group education, a Fitbit, access to FitViz (a Fitbit-compatible app), and 4 biweekly phone calls from a PT over 8 weeks. Participants then continued using Fitbit and FitViz independently up to week 12. The delay group (DG) received a monthly electronic newsletter in weeks 1 to 12 and started the same intervention in week 14. Participants were assessed in weeks 13, 26, and 39. The primary outcome was time spent in daily moderate-to-vigorous physical activity (MVPA; in bouts ≥10 min) measured with a SenseWear Mini. Secondary outcomes included daily steps, time spent in purposeful activity and sedentary behavior, Knee Injury and OA Outcome Score, Patient Health Questionnaire-9, Partners in Health Scale, Theory of Planned Behavior Questionnaire, and Self-Reported Habit Index.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>We enrolled 51 participants (IG: n=26 and DG: n=25). Compared with the IG, the DG accumulated significantly more MVPA time at baseline. The adjusted mean difference in MVPA was 13.1 min per day (95% CI 1.6 to 24.5). A significant effect was also found in the adjusted mean difference in perceived sitting habit at work (0.7; 95% CI 0.2 to 1.2) and during leisure activities (0.7; 95% CI 0.2 to 1.2). No significant effect was found in the remaining secondary outcomes.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions</jats:title> <jats:p>A 12-week multifaceted program with the use of a wearable device, an app, and PT counseling improved physical activity in people with knee OA.</jats:p> </jats:sec> <jats:sec> <jats:title>Trial Registration</jats:title> <jats:p>ClinicalTrials.gov NCT02585323; https://clinicaltrials.gov/ct2/show/NCT02585323</jats:p> </jats:sec>

Twenty‐Four Hour Activity and Sleep Profiles for Adults Living with Arthritis: Habits Matter

“…We conducted a cross-sectional cohort study using baseline data from 2 randomized clinical trials studying the effect of physical activity counseling for people with knee OA (SuPRA study), or RA or SLE (The Effectiveness of Physical Activity Monitoring in Inflammatory Arthritis [OPAM-IA] study) (33,34). Participants were eligible if they had a physician diagnosis of RA, SLE, or knee OA, or, in the case of undiagnosed knee OA, were age ≥50 years and had experienced pain or discomfort in or around the knee during the previous year lasting ≥28 days (35).…”

“…Participants were eligible if they had a physician diagnosis of RA, SLE, or knee OA, or, in the case of undiagnosed knee OA, were age ≥50 years and had experienced pain or discomfort in or around the knee during the previous year lasting ≥28 days (35). Participants had to be able to participate in physical activities without health professional supervision, have no prior experience with using wearable activity monitors, and have email and internet access (33,34). Participants were recruited from facilities offering arthritis care in 2 large metropolitan health care authorities in British Columbia, Canada.…”

“…Participants were recruited from facilities offering arthritis care in 2 large metropolitan health care authorities in British Columbia, Canada. Recruitment information was also posted on research websites, Facebook, Twitter, Kajiji, and Craigslist (33,34).…”

“…All statistical analyses were conducted using SAS software, version 9.4. Both studies were carried out in compliance with the Helsinki declaration for conducting research with humans and received ethical approval from the University of British Columbia, Vancouver, Canada (SuPRA study H15-02038 and OPAM-IA study H15-01843) (33,34).…”

Clinical severity of serum S100A12 levels in patients with osteoarthritis and S100A12 open inflammation of osteoarthritis model by NLRP3

“…In terms of clinical manifestation, it is mainly characterized by repeated and progressive pain and swelling of the joint, along with joint deformities and movement disorders. 12 The etiology of OA is not yet fully understood. 13 In recent years, accumulative studies have shown that various cytokines play important roles in the occurrence and development of OA, which are closely associated with the functional changes of synovium, articular cartilage, and subchondral cartilage.…”