Effects of a Cereal Bar with a Combination of Phytoestrogens on the Climacteric Symptoms: A Placebo-Controlled, Randomized Trial

Frigo, Maiara; Barros, Evayne de; Santos, Patrícia Cerqueira; Peres, G.; Weber, Jucieli; Zanelatto, Carla; Koehnlein, Eloá Angélica

doi:10.1080/07315724.2021.1884143

Cited by 6 publications

(12 citation statements)

References 36 publications

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“…49 Several studies suggest that using different types of phytoestrogens can be a safe, accessible, and low-risk method compared with hormone therapy during the postmenopausal period. [50][51][52] Similar to our findings, a systematic review and meta-analysis by Hooper et al 53 indicates beneficial effects of isoflavone-rich soy products on estradiol elevation, LH, and FSH reduction. Thomas et al 50 revealed that fenugreek seed extract increases estradiol, progesterone, and free testosterone and decreases SHBG and FSH due to its phytoestrogenic effect.…”

Section: Discussionsupporting

confidence: 90%

“…During the menopausal transition, sharply decreased estrogen levels and increased FSH levels in the long term might be responsible for the high risk of osteoporosis and CVD in postmenopausal women 49 . Several studies suggest that using different types of phytoestrogens can be a safe, accessible, and low-risk method compared with hormone therapy during the postmenopausal period 50-52 . Similar to our findings, a systematic review and meta-analysis by Hooper et al 53 indicates beneficial effects of isoflavone-rich soy products on estradiol elevation, LH, and FSH reduction.…”

Section: Discussionsupporting

confidence: 86%

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The effect of Cornus mas fruit extract on vasomotor symptoms and sex hormones in postmenopausal women: a randomized, double-blind, clinical trial

et al. 2022

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 86%

The effect of Cornus mas fruit extract on vasomotor symptoms and sex hormones in postmenopausal women: a randomized, double-blind, clinical trial

et al. 2022

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“…The BKI consists of eleven symptoms (vasomotor, paresthesia, insomnia, nervousness, melancholy, vertigo, weakness, arthralgia/myalgia, headache, palpitations, and tingling), to which different scores are attributed. The total score is classified as light ( 19), moderate (from 20 to 35) or intense (! 36).…”

Section: Methodsmentioning

confidence: 99%

Does Obesity Aggravate Climacteric Symptoms in Postmenopausal Women?

Dechichi

Rodrigues

Puga

et al. 2022

Rev Bras Ginecol Obstet

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Objective To determine if there is a correlation between body mass index (BMI) and climacteric symptoms in postmenopausal women. Methods The study sample was composed of 109 postmenopausal women with a mean age of 57 ± 8 years, mean body mass index (BMI) of 30 ± 6 kg/m2, and 8 ± 8 years after menopause. For the assessment of the climacteric symptoms, the Blatt-Kupperman Index (BKI), the Menopause Rating Scale (MRS), and the Cervantes Scale (CS) were used. Data analysis was performed through the Chi-squared test, analysis of variance (ANOVA) with the Bonferroni post hoc test, and multiple linear regression. The level of significance adopted was of p < 0.05. The statistical analyses were performed using the Statistical Package for the Social Sciences (IBM SPSS Statistics for Windows, IBM Corp., Armonk, NY, United States) software, version 26.0. Results The multiple linear regression showed a positive association (p < 0.01) between BMI values and menopause symptoms when adjusted for age and time after menopause in the 3 questionnaires used (BKI: B = 0.432; CS: B = 304; and MRS: B = 302). Regarding symptom scores, the obese women had higher mean scores (p < 0.05) when compared to eutrophic women (BKI = 28 ± 10 and 20 ± 10; and MRS = 20 ± 10 and 13 ± 7, respectively). In the Chi-squared analysis, 28% of obese women had severe symptoms and 46% had moderate symptoms, while only 1% and 46% of eutrophic women had these same symptoms. Conclusion There is an association between BMI and climacteric symptoms, and overweight or obese women have more intense and moderate symptoms than eutrophic women.

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“…It is a transitional period for women from maturity to old age.Take a closer look, menopause could be divided into three sub-periods, including premenopausal, perimenopausal, and postmenopausal stages Before 40 years old, women experience the regular menstruation cycle every month, in a long period called premenopause.However, starting from the age of 40, females may observe subtle changes in the length of menstruation cycles, in the transition period of perimenopause. The final stage, the postmenopausal state comes after 1 months of pausimenia [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

“…However, few studies have specifically examine about the exact reasons causing these downsides and the helpful treatments. Currently therapy treating menopausal uncomfortness, such as estrogen plus progestogen therapy (EPT), which generates negative impacts on human health by altering female hormone levels, warm acupuncture, and N-3 dietary therapy just have effects alleviating serious symptoms [1,4,[7][8][9]. This paper will take psychological problems as the main starting point,and introduce the pathogenesis and management measures of psychological symptoms in detail…”

Section: Introductionmentioning

confidence: 99%

Management of menopausal physiological symptoms

Su¹,

Zhang²

2022

HSET

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With the development of our society, people are putting more and more emphasis on women’s health. Perimenopause is a period that women must experience. When women are in perimenopause, their hormone levels will change greatly, resulting in obvious physiological changes, such as hot flashes, night sweats and other physical symptoms,such as muscle and joint problems, urinal system, and cardiac problems.In fact, there will be a series of psychological changes, such as depression, anxiety and so on, but most of the symptoms will be covered up by physical symptoms, leading to misdiagnosis and missed diagnosis. When patients have negative emotions, they will continue to have an impact on the development of the disease, and even accelerate the development of the disease, gradually forming a vicious circle.It is very important for perimenopausal women to do a good job in hormone supplementation and mental health care, and it is also the key to help perimenopausal women alleviate the physiological and psychological changes caused by menopause. MHT is the first-line recommended treatment, which can also be supplemented by other treatments, such as physical exercise, yoga, warm acupuncture, etc

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Effects of a Cereal Bar with a Combination of Phytoestrogens on the Climacteric Symptoms: A Placebo-Controlled, Randomized Trial

Cited by 6 publications

References 36 publications

The effect of Cornus mas fruit extract on vasomotor symptoms and sex hormones in postmenopausal women: a randomized, double-blind, clinical trial

The effect of Cornus mas fruit extract on vasomotor symptoms and sex hormones in postmenopausal women: a randomized, double-blind, clinical trial

Does Obesity Aggravate Climacteric Symptoms in Postmenopausal Women?

Management of menopausal physiological symptoms

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