Effects of a high-molecular-weight cranberry fraction on growth, biofilm formation and adherence of Porphyromonas gingivalis

Labrecque, Julie; Bodet, Charles; Chandad, Fatiha; Grenier, Daniel

doi:10.1093/jac/dkl220

Cited by 128 publications

(112 citation statements)

References 13 publications

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“…These results were similar to those reported by Ahuja et al [13] and Labrecque et al [28] who observed that cranberry juice concentrate had neither antibacterial activity on uropathogenic E. coli nor on Porphyromonas gingivalis. The results were also similar to those obtained by Wang et al [31] who suggested that the inhibitory effect of resveratrol, a naturally occurring phytoalexin, on P. mirabilis swarming and virulence factors expression is unlikely to be due to its inhibitory effect on bacterial growth.…”

Section: Discussionsupporting

confidence: 92%

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Effect of Ibicella lutea on uropathogenic Proteus mirabilis growth, virulence, and biofilm formation

Sosa

Zunino

2009

J Infect Dev Ctries

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Background: Proteus mirabilis, an important uropathogen that can cause complicated urinary tract infections (UTI), has emerged as a therapeutic problem following mutations that compromise the use of antimicrobial drugs. Due to the serious effects associated with uropathogenic P. mirabilis and the problems related to the use of antibiotics, it is necessary to develop alternative strategies for its control. The objective of this study was to assess the effect of Ibicella lutea extract, a South American indigenous plant, on growth, virulence and biofilm production of uropathogenic P. mirabilis. Methodology: This study was based on the extract generation and the assessment of its effect on bacterial features related to virulence. These assays involved determination of antibacterial activity, swarming motility, Western blot to assess expression of fimbriae and flagella, biofilms formation, haemagglutination, haemolysis, and electron microscopy. Results and Conclusions: I. lutea extract had an effect on bacterial growth rate and bacterial morphology. It also affected P. mirabilis swarming differentiation, hemagglutination and biofilm formation on glass and polystyrene. These findings suggest that I. lutea may have a role as an agent for the control of P. mirabilis UTI.

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Section: Discussionsupporting

confidence: 92%

“…The effect of I. lutea extract on biofilms formation was performed according to Pitts et al [28]. Bacteria were statically grown in polystyrene multi-well plates and in glass tubes containing unmodified LB or LB supplemented with I. lutea (1 and 2 mg ml -1 ) for 48 h at 37°C.…”

Section: Biofilm Formation Assaymentioning

confidence: 99%

Effect of Ibicella lutea on uropathogenic Proteus mirabilis growth, virulence, and biofilm formation

Sosa

Zunino

2009

J Infect Dev Ctries

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“…Labrecque et al 4) reported that NDM inhibited biofilm formation by P. gingivalis. NDM fraction contains 0.35% anthocyanins and 65.1% proanthocyanidins 4,13) .…”

Section: Discussionmentioning

confidence: 99%

Inhibitory Effect of Cranberry Polyphenol on Cariogenic Bacteria

Yamanaka-Okada

Sato

Kouchi

et al. 2008

Bull. Tokyo Dent. Coll.

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The purpose of this study was to investigate the effect of cranberry polyphenol fraction on mutans streptococci. Hydrophobicity is an important factor in the adherence of bacteria to the tooth surface. We found that cranberry polyphenol fraction significantly decreased the hydrophobicity of Streptococcus sobrinus 6715, Streptococcus mutans MT8148R and JC2 in a dose-dependent manner (pϽ0.05). Biofilm formation by S. sobrinus 6715 and S. mutans MT8148R was inhibited by 100g/ml cranberry polyphenol fraction (pϽ0.01). When dosage was increased to 500g/ml, biofilm formation by S. mutans JC2 was significantly inhibited (pϽ0.05). Addition of 500g/ml cranberry polyphenol fraction to medium inhibited growth of S. mutans MT8148R compared with the control (pϽ0.05).

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“…NDM fraction contains 0.35% anthocyanins and 65.1% proanthocyanidins 4,13) . Our polyphenol fraction sample contained 34% flavonol, including catechins and primary components such as proanthocyanidins.…”

Section: Discussionmentioning

confidence: 99%

Longitudinal Study on Influence of Prolonged Non-nutritive Sucking Habits on Dental Caries in Japanese Children from 1.5 to 3 Years of Age

Yonezu

Yakushiji

2008

Bull. Tokyo Dent. Coll.

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Effects of a high-molecular-weight cranberry fraction on growth, biofilm formation and adherence of Porphyromonas gingivalis

Abstract: Our data suggest that cranberry constituents may have a beneficial effect for the prevention and treatment of periodontitis by reducing the capacity of P. gingivalis to colonize periodontal sites.

Cited by 128 publications

References 13 publications

Effect of Ibicella lutea on uropathogenic Proteus mirabilis growth, virulence, and biofilm formation

Effect of Ibicella lutea on uropathogenic Proteus mirabilis growth, virulence, and biofilm formation

Inhibitory Effect of Cranberry Polyphenol on Cariogenic Bacteria

Longitudinal Study on Influence of Prolonged Non-nutritive Sucking Habits on Dental Caries in Japanese Children from 1.5 to 3 Years of Age

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