Effects of a Low-FODMAP Diet on Irritable Bowel Syndrome in Both Children and Adults—A Narrative Review

Morariu, Ionela-Daniela; Avasilcai, Liliana; Vieriu, Madalina; Lupu, Vasile Valeriu; Morariu, Branco-Adrian; Lupu, Ancuța; Morariu, Paula-Cristina; Pop, Oana-Lelia; Starcea, Iuliana Magalena; Trandafir, Laura

doi:10.3390/nu15102295

Cited by 13 publications

(9 citation statements)

References 95 publications

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“…There is significant evidence that the follow-up of a low-FODMAP diet might be a feasible first-line therapeutic strategy to reduce stomach discomfort, pain, bloating, and quality of life for patients with IBS [ 32 ] and that around 70% of FM patients also report IBS symptoms [ 33 ].…”

Section: Resultsmentioning

confidence: 99%

Restrictive Diets in Patients with Fibromyalgia: State of the Art

Almirall,

Musté,

Serrat

et al. 2024

Biomedicines

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Around 20–30% of Fibromyalgia patients modify their dietary habits after diagnosis, including avoiding certain food groups such as cereals. In this systematic review, we used the PRISMA guidelines to select the main studies that have evaluated the effectiveness of restrictive diets, including elimination and vegetarian diets, in patients with Fibromyalgia. Data on vegetarian/vegan diets are more consistent than data on elimination diets due to higher quality and better results of the published studies. Although the results are favorable in most of the studies, their heterogenicity and the scarce and low quality of the evidence (small number of patients included, often non-randomized and uncontrolled studies and multiple confounding factors and biases) does not allow for a positive recommendation about these restrictive diets in Fibromyalgia patients. Several factors other than food restriction could influence the symptomatic and functional improvements observed after restrictive diets, such as the placebo effect, weight loss that often occurs, coexistence with gastrointestinal diseases and positive effects of unrestricted foods. We must advance more and improve in our knowledge of the effectiveness of restrictive diets and variables related to them before recommending them systematically to all patients with Fibromyalgia. Randomized, placebo-controlled trials with large sample sizes, longer follow-up periods and standardized outcome measures that explore predictors of dietary response are needed to better understand the relationship between Fibromyalgia and nutrition.

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Section: Resultsmentioning

confidence: 99%

Restrictive Diets in Patients with Fibromyalgia: State of the Art

Almirall,

Musté,

Serrat

et al. 2024

Biomedicines

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show abstract

“…High-FODMAP foods are those that contain more than 4 g of lactose, more than 0.3 g of mannitol, sorbitol, galacto-oligosaccharides, or fructans. So, it is possible to categorize foods by considering their FODMAP amount [46]. FODMAPs are poorly absorbed and fermented by intestinal bacteria.…”

Section: Fodmap Intolerancementioning

confidence: 99%

“…Nowadays, the pathogenesis of IBS is still not completely understood, but different studies have demonstrated that diet plays an important role in symptom management [46]. The most evidence-based diet is the low-FODMAP diet (LFD), which was found to be effective in IBS treatment [49,52].…”

Section: Uses Of Low-fodmap Diets In Clinical Practicementioning

confidence: 99%

Myths and Facts about Food Intolerance: A Narrative Review

Zingone,

Bertin,

Maniero

et al. 2023

Nutrients

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Most adverse reactions to food are patient self-reported and not based on validated tests but nevertheless lead to dietary restrictions, with patients believing that these restrictions will improve their symptoms and quality of life. We aimed to clarify the myths and reality of common food intolerances, giving clinicians a guide on diagnosing and treating these cases. We performed a narrative review of the latest evidence on the widespread food intolerances reported by our patients, giving indications on the clinical presentations, possible tests, and dietary suggestions, and underlining the myths and reality. While lactose intolerance and hereditary fructose intolerance are based on well-defined mechanisms and have validated diagnostic tests, non-coeliac gluten sensitivity and fermentable oligosaccharide, disaccharide, monosaccharide, and polyol (FODMAP) intolerance are mainly based on patients’ reports. Others, like non-hereditary fructose, sorbitol, and histamine intolerance, still need more evidence and often cause unnecessary dietary restrictions. Finally, the main outcome of the present review is that the medical community should work to reduce the spread of unvalidated tests, the leading cause of the problematic management of our patients.

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“…FODMAPs are a group of compounds that can produce gas through gut microbial fermentation and, in susceptible individuals, can worsen symptoms such as abdominal bloating and other gastrointestinal symptoms. The low FODMAP diet improves symptoms in 70% of IBS patients [23].…”

Section: Introductionmentioning

confidence: 98%

Do Herbal Supplements and Probiotics Complement Antibiotics and Diet in the Management of SIBO? A Randomized Clinical Trial

Redondo-Cuevas,

Belloch,

Martín-Carbonell

et al. 2024

Nutrients

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Small intestinal bacterial overgrowth (SIBO) arises from dysbiosis in the small intestine, manifesting with abdominal symptoms. This study aims to assess the efficacy of combined antibiotic therapy, herbal supplements, probiotics, and dietary modifications in SIBO management. A total of 179 SIBO-diagnosed patients underwent clinical evaluation and breath testing. Patients were categorized into hydrogen (H2-SIBO) and methane (CH4-SIBO) groups. The control group received standard antibiotic therapy and a low-FODMAP diet, while the intervention group received additional herbal antibiotics, probiotics, and prebiotics. After treatment, both groups exhibited reduced gas levels, particularly in CH4-SIBO. Clinical remission rates were higher in the intervention group, especially in CH4-SIBO cases. Logistic regression analysis showed gas concentrations at diagnosis as significant predictors of treatment success. In conclusion, adjunctive herbal supplements and probiotics did not significantly impact gas levels, but showed potential for clinical improvement, especially in CH4-SIBO.

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Effects of a Low-FODMAP Diet on Irritable Bowel Syndrome in Both Children and Adults—A Narrative Review

Cited by 13 publications

References 95 publications

Restrictive Diets in Patients with Fibromyalgia: State of the Art

Restrictive Diets in Patients with Fibromyalgia: State of the Art

Myths and Facts about Food Intolerance: A Narrative Review

Do Herbal Supplements and Probiotics Complement Antibiotics and Diet in the Management of SIBO? A Randomized Clinical Trial

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