Effects of a Persistent Binge Drinking Pattern of Alcohol Consumption in Young People: A Follow-Up Study Using Event-Related Potentials

López‐Caneda, Eduardo; Cadaveira, Fernando; Crego, Alberto; Doallo, Sonia; Corral, Montserrat; Gómez-Suárez, Ana; Holguı́n, Socorro Rodrı́guez

doi:10.1093/alcalc/agt046

Cited by 71 publications

(73 citation statements)

References 73 publications

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“…In a previous study by our research group, electrophysiological findings have revealed anomalies in neural activity involving WM/attention processes after 2 years of a stable BD pattern. These results may reflect the recruitment of additional resources for adequate task performance and may compensate underlying dysfunctions (López-Caneda et al, 2013).…”

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 95%

Working memory over a six-year period in young binge drinkers

Carbia

Cadaveira

López‐Caneda

et al. 2017

Alcohol

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Adolescence and early adulthood are periods of particular vulnerability to the neurotoxic effects of alcohol. Young people with alcohol-use disorders display deficits in working memory (WM). This function is supported by the prefrontal cortex, a late-maturing brain region. However, little is known about the progression of cognitive dysfunctions associated with a binge-drinking (BD) pattern of alcohol consumption among non-clinical adolescents. The objective of this study was to analyze the relationship between BD trajectory and WM in university students. An initial sample of 155 male and female first-year university students was followed prospectively over 6 years. The participants were classified as stable non-BDs, stable BDs, and ex-BDs, according to the third item of the Alcohol Use Disorders Identification Test (AUDIT). WM was assessed using the Self-Ordered Pointing Task. Generalized linear mixed models were applied. The results showed that stable BDs committed more total perseverative errors and showed a lower WM span in the difficult blocks than stable non-BDs. Difficulties in WM span showed some improvement, whereas perseveration errors remained constant throughout the follow-ups in the stable BDs. There were no significant differences between ex-BDs and non-BDs. In conclusion, stable BD is associated with WM deficits, particularly perseverations and low WM span in demanding trials, when compensatory mechanisms may no longer be successful. The partial improvement in WM span may support the notion of a neuromaturational delay, whereas the temporal stability of perseveration deficits may reflect either neurotoxic effects of alcohol or premorbid characteristics. Abandoning the BD pattern of alcohol consumption may lead to partial recovery.

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Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 95%

Working memory over a six-year period in young binge drinkers

Carbia

Cadaveira

López‐Caneda

et al. 2017

Alcohol

View full text Add to dashboard Cite

show abstract

“…The binge drinking score [37], considering the consumption speed, the frequency of drunkenness episodes, and the percentage of drunkenness episodes compared to the total number of drinking episodes, was used to categorize students together with classical alcohol-related variables [46]. Importantly, in the current study, an alcohol dose corresponded to 10 g of pure ethanol.…”

Section: Participantsmentioning

confidence: 99%

Executive Impairments in Binge Drinking: Evidence for a Specific Performance-Monitoring Difficulty during Alcohol-Related Processing

et al. 2018

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This study evaluated inhibition and performance-monitoring abilities through the explicit processing of alcohol cues. Twenty-two binge drinkers (BD) and 22 control participants performed a speeded Go/No-Go task using pictures of alcohol and soft cans as Go and No-Go targets. This task measures inhibitory control and performance monitoring (i.e., task adjustment through errors and feedback processing) during the explicit processing of alcohol cues. Groups did not significantly differ regarding inhibition abilities. However, BD had poorer performance-monitoring abilities, reflected by a difficulty to adjust after errors, especially when these errors were related to alcohol cues. These findings suggest that the explicit processing of alcohol cues negatively impacts cognitive abilities among BD.

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“…Electrophysiological studies first showed that the event-related potentials associated with attentional and executive processes have abnormal latency and amplitude during working memory tasks in binge drinking (Ehlers et al, 2007; Crego et al, 2012; Lopez-Caneda et al, 2013). Moreover, neuroimaging studies suggested the brain areas involved: anatomical studies showed reduced cortical thickness among male binge drinkers (Squeglia et al, 2012) and reduced activations in prefrontal areas during memory and executive tasks were observed (Schweinsburg et al, 2010, 2011; Xiao et al, 2013).…”

Section: Reflective System In Binge Drinkingmentioning

confidence: 99%

Beyond Inhibition: A Dual-Process Perspective to Renew the Exploration of Binge Drinking

Lannoy

Billieux

Maurage

2014

Front. Hum. Neurosci.

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Binge drinking is a widespread alcohol-consumption pattern in youth and is linked to cognitive consequences, mostly for executive functions. However, other crucial factors remain less explored in binge drinking and notably the emotional-automatic processes. Dual-process model postulates that addictive disorders are not only due to impaired reflective system (involved in deliberate behaviors), but rather to an imbalance between under-activated reflective system and over-activated affective-automatic one (involved in impulsive behaviors). This proposal has been confirmed in alcohol-dependence, but has not been tested in binge drinking. The observation of comparable impairments in binge drinking and alcohol-dependence led to the “continuum hypothesis,” suggesting similar deficits across different alcohol-related disorders. In this perspective, applying the dual-process model to binge drinking might renew the understanding of this continuum hypothesis. A three-axes research agenda will be proposed, exploring: (1) the affective-automatic system in binge drinking; (2) the systems’ interactions and imbalance in binge drinking; (3) the evolution of this imbalance in the transition between binge drinking and alcohol-dependence.

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Effects of a Persistent Binge Drinking Pattern of Alcohol Consumption in Young People: A Follow-Up Study Using Event-Related Potentials

Cited by 71 publications

References 73 publications

Working memory over a six-year period in young binge drinkers

Working memory over a six-year period in young binge drinkers

Executive Impairments in Binge Drinking: Evidence for a Specific Performance-Monitoring Difficulty during Alcohol-Related Processing

Beyond Inhibition: A Dual-Process Perspective to Renew the Exploration of Binge Drinking

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