Effects of a preconception lifestyle intervention in obese infertile women on diet and physical activity; A secondary analysis of a randomized controlled trial

Elten, Tessa M. van; Karsten, Matty D. A.; Geelen, Anouk; Oers, Anne M. van; Poppel, Mireille N. M. van; Groen, Henk; Gemke, Reinoud J. B. J.; Mol, Ben Willem J.; Mutsaerts, Meike; Roseboom, Tessa J.; Hoek, Annemieke

doi:10.1371/journal.pone.0206888

Cited by 23 publications

(20 citation statements)

References 43 publications

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“…While many studies have explored weight maintenance in pregnant women, focused primarily on limiting gestational weight gain, few have targeted the vital preconception phase [ 12 , 24 ]. Women who intend to become pregnant are more amenable to lifestyle advice, so interventions during this time may be more effective than during any other period in life [ 25 ].…”

Section: Introductionmentioning

confidence: 99%

Creating Healthy Change in the Preconception Period for Women with Overweight or Obesity: A Qualitative Study Using the Information–Motivation–Behavioural Skills Model

Scott

Oxlad

Dodd

et al. 2020

JCM

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Worldwide, half of women begin a pregnancy with overweight or obesity, which increases the risk of pregnancy and birth complications and adversely affects the lifelong health of the offspring. In order for metabolic changes to influence the gestational environment, research suggests that weight loss should take place before conception. This study aimed to understand women’s emotional and social contexts, knowledge, motivations, skills and self-efficacy in making healthy change. Semi-structured interviews conducted with twenty-three women with overweight or obesity, informed by the Information–Motivation–Behavioural Skills (IMB) model, were analysed using reflexive thematic analysis. Information-related themes identified included poor health risk knowledge, healthy food decisions and health versus convenience. The Motivation themes comprised taking responsibility, flexible options, social expectations, interpersonal challenges and accountability. Behavioural Skills entailed themes such as the mental battle, time management, self-care and inspiration. An environmental factor was identified in affordability—limiting access to healthier alternatives. Women wanted simple, flexible options that considered family commitments, time and budgetary constraints. Unprompted, several mentioned the importance of psychological support in managing setbacks, stress and maintaining motivation. Strategies for enhancing self-efficacy and motivational support are required to enable longstanding health behaviour change. Findings will inform intervention mapping development of an eHealth solution for women preconception.

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Section: Introductionmentioning

confidence: 99%

Creating Healthy Change in the Preconception Period for Women with Overweight or Obesity: A Qualitative Study Using the Information–Motivation–Behavioural Skills Model

Scott

Oxlad

Dodd

et al. 2020

JCM

View full text Add to dashboard Cite

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“…Lifestyle interventions of >12 months duration showed more consistent weight loss results compared to interventions of <6 months duration (Naslund et al, 2017). We have shown that a lifestyle intervention, offered during the preconception period when women are particularly receptive to lifestyle advice (McBride, Emmons, & Lipkus, 2003), is effective in improving lifestyle (van Elten et al, 2018), reducing body weight and improving cardiometabolic health (van Dammen et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

A lifestyle intervention randomized controlled trial in obese women with infertility improved body composition among those who experienced childhood adversity

et al. 2020

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Previous research indicates that tailoring lifestyle interventions to participant characteristics optimizes intervention effectiveness. Our objective was to assess whether the effects of a preconception lifestyle intervention in obese infertile women depended on women's exposure to adversity in childhood. A follow‐up of a preconception lifestyle intervention randomized controlled trial (the LIFEstyle study) was conducted in the Netherlands among 577 infertile women (age 18–39 years) with a body mass index (BMI) ≥29 kg/m2 at time of randomization; N = 110 (19%) consented to the follow‐up assessment, 6 years later. A 6‐month preconception lifestyle intervention aimed weight loss through improving diet and increasing physical activity. The control group received care as usual. Outcome measures included weight, BMI, waist and hip circumference, body fat percentage, blood pressure and metabolic syndrome. The potential moderator, childhood adversity, was assessed with the Life Events Checklist‐5 questionnaire. Among the 110 women in our follow‐up study, n = 65 (59%) reported no childhood adverse events, n = 28 (25.5%) reported 1 type of childhood adverse events and n = 17 (15.5%) reported ≥2 types of childhood adverse events. Regression models showed significant interactions between childhood adversity and effects of lifestyle intervention at the 6‐year follow‐up. Among women who experienced childhood adversity, the intervention significantly reduced weight (−10.0 [95% CI −18.5 to −1.5] kg, p = 0.02), BMI (−3.2 [−6.1 to −0.2] kg/m2, p = 0.04) and body fat percentage (−4.5 [95% CI −7.2 to −1.9] p < 0.01). Among women without childhood adversity, the intervention did not affect these outcomes (2.7 [−3.9 to 9.4] kg, p = 0.42), (0.9 [−1.4 to 3.3] kg/m2, p = 0.42) and (1.7 [95% CI −0.3 to 3.7] p = 0.10), respectively. Having a history of childhood adversity modified the effect of a preconception lifestyle intervention on women's body composition. If replicated, it may be important to consider childhood adversity as a determinant of lifestyle intervention effectiveness.

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“…The nutritional status of women before conception can affect the critical development process during pregnancy and child born. In addition, women who intend to become pregnant are more vulnerable to suggestions for lifestyle changes [3].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Moringa oleifera to Hemoglobin Levels of Preconception Women in the Health Center Tibawa District Tibawa, Gorontalo

Mustapa

Hadju

Indriasari

et al. 2020

Open Access Maced J Med Sci

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BACKGROUND: The maternal mortality rate (MMR) in Gorontalo Province is still high at 194.7/100,000 live births. Causes of high MMR include bleeding and anemia. AIM: This study aimed to assess the effect of giving Moringa oleifera extract on the hemoglobin concentration of preconception women in the area of the health center Tibawa. METHODS: This research method was a true experiment with a type of randomized controlled double-blind intervention of WUS aged 15–35 years with a sample of 44 people selected using purposive sampling techniques collected by trained personnel, including general data of respondents. RESULTS: The results showed nutritional status and hemoglobin concentration in the treatment group of 12 people (54%) with an increase in Hb 0.1–1.0 g/dl and ten people (45%) with an increase in Hb 1.5–2.0 g/dl after the intervention, whereas in the control group of five people (22%) with an increase in Hb 0.1–1.0 g/dl and 17 people (77%), there was no increase in Hb after the intervention. There was a significant difference in hemoglobin concentration in the treatment group with p = 0.000 (p < 0.05) with an average increase of 1.54. There was a significant difference in hemoglobin concentration in controls with p = 0.025 (p < 0.05) with an average increase of 0.22. CONCLUSION: There is a difference in the effect between administration of M. oleifera extract that is more effective on hemoglobin concentration compared to MMN. It is hoped that in supporting government programs in reducing anemia in women of childbearing age, M. oleifera extract can be an alternative to giving blood-added tablets MMN.

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Effects of a preconception lifestyle intervention in obese infertile women on diet and physical activity; A secondary analysis of a randomized controlled trial

Cited by 23 publications

References 43 publications

Creating Healthy Change in the Preconception Period for Women with Overweight or Obesity: A Qualitative Study Using the Information–Motivation–Behavioural Skills Model

Creating Healthy Change in the Preconception Period for Women with Overweight or Obesity: A Qualitative Study Using the Information–Motivation–Behavioural Skills Model

A lifestyle intervention randomized controlled trial in obese women with infertility improved body composition among those who experienced childhood adversity

The Effect of Moringa oleifera to Hemoglobin Levels of Preconception Women in the Health Center Tibawa District Tibawa, Gorontalo

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