“…The leather solid waste produced by the tanning industry is rich in collagen and chromium resources. If it is recycled and reused, it not only eliminates environmental pollution from leather waste but also makes full use of the original leather and chrome resources, which meets the requirements of a circular economy and sustainable development of the modern tanning industry. − There are more studies on the preparation of collagen into microspheres, and the main methods are emulsion cross-linking, − spray drying, − self-assembly, − and template method. , Self-assembly is a technique by which the basic structural units spontaneously form an ordered structure. Current studies on the preparation of collagen microspheres by self-assembly methods have focused on natural plant tannins, namely, grape seed proanthocyanidin, tannin acid, tea catechin, and other plant polyphenols. ,− This type of study focuses on the structure of microspheres obtained by self-assembly with collagen in the form of hydrogen and hydrophobic bonds using the phenolic hydroxyl groups of natural tannins and the structural characteristics of their benzene rings.…”