Effects of a Protected Vitamin and Choline Supplement in the Transition Period on Dairy Cow Metabolic Parameters and Health

Evans, E.; Mair, D.T.; Gauthier, Robert C.; Fontaine, J L

doi:10.15232/s1080-7446(15)31082-2

Cited by 4 publications

(3 citation statements)

References 19 publications

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“…We did detect lower mean blood BHB at wk 3 postpartum only, and a lower degree of liver fat infiltration in RPBC among primiparous cows at 4 DIM. A similar magnitude of reduction in mean BHB, specifically at wk 2 postpartum, was observed in a field case study with a RPBC supplement (Evans et al, 2006b). We note that DMI was high in the close-up dry cows, and liver fat percentages were low.…”

Section: Discussionsupporting

confidence: 82%

Effect of rumen-protected B vitamins and choline supplementation on health, production, and reproduction in transition dairy cows

Morrison

Reinhardt

Leclerc

et al. 2018

Journal of Dairy Science

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The objectives were to determine the effects of a rumen-protected blend of B vitamins and choline (RPBC) on the incidence of health disorders, milk yield, and reproduction in early lactation and the effects on gene expression and liver fat infiltration. A randomized controlled trial in 3 commercial dairy herds (n = 1,346 cows with group as the experimental unit; experiment 1) and a university research herd (n = 50 cows with cow as the experimental unit; experiment 2) evaluated the use of 100 g/cow per d of commercially available proprietary RPBC supplement (Transition VB, Jefo, St. Hyacinthe, Quebec, Canada), or a placebo, fed 3 wk before to 3 wk after calving. In experiment 2 liver biopsies were taken at 4 and 14 ± 1 d in milk to measure triacylglycerol concentrations and expression of 28 genes selected to represent relevant aspects of liver metabolism. Treatment effects were assessed using multivariable mixed logistic regression models for binary health and reproductive outcomes; linear regression models for milk yield, dry matter intake, and liver outcomes; and survival analysis for time insemination and pregnancy. In experiment 1, treatment did not have an effect on the incidence of hyperketonemia (blood β-hydroxybutyrate ≥ 1.2 mmol/L; cumulative incidence to 3 wk postpartum of 28 to 30%), clinical health disorders, or udder edema. The prevalence of anovulation at 8 wk postpartum was 11% in the treatment group and 23% in the control but did not differ statistically given group-level randomization. Pregnancy at first insemination (33 and 35%) and median time to pregnancy to 200 d in milk (96 and 97 d) were not different between treatment and control, respectively. No difference was observed between treatment groups in milk yield or components through the first 3 Dairy Herd Improvement Association test days (44 kg/d in both groups, accounting for parity and components). In experiment 2, there were no differences between treatment groups in feed intake. Mean blood β-hydroxybutyrate was lower at wk 3 in RPBC (0.6 vs. 0.9 ± 0.12 mmol/L) with no difference between treatments for mean blood concentrations of fatty acids (wk -1 or 1) and β-hydroxybutyrate at wk 1 or 2. The gene for acyl-CoA oxidase 1 (ACOX1) had lower mRNA abundance in RPBC with no difference between treatments for the other genes, but the expression of half of the genes assessed differed with days in milk. Liver triacylglycerol was lower in primiparous cows at 4 d in milk in RPBC (2.0 vs. 4.4 ± 1.2%) but not at 14 d in milk (2.2 vs. 3.2 ± 0.97%) with no treatment effect in multiparous cows (4.6 ± 0.8%). Accounting for parity, days in milk, fat and protein percentages, repeated test days, and a random effect of cow, no significant difference was observed between treatments in milk yield across the first 3 Dairy Herd Improvement Association tests (41.2 ± 1.3 in RPBC vs. 38.0 ± 1.4 kg/d in control). Under the diet and management conditions of the field study including low prevalence of clinical health disorders, in experiment 1 we did not detect a bene...

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Section: Discussionsupporting

confidence: 82%

Effect of rumen-protected B vitamins and choline supplementation on health, production, and reproduction in transition dairy cows

Morrison

Reinhardt

Leclerc

et al. 2018

Journal of Dairy Science

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“…Dry matter intake was not affected by the addition of FA in dairy cows, indicating that folic acid supplementation had no significant impact on DMI. However, according to other research, FA supplementation improved DM intake in transition dairy cows (Evans et al, 2006) and in weaned dairy calves (Wang et al, 2019). 091 2 nd International Scientific Conference "Agriculture and Futuristic Challenges (Food Security: Challenges and Confrontation)", Faculty of Agriculture, Al-Azhar University, Cairo, Egypt, October 10 th -11 th , 2023.…”

Section: Feed Intake and Feed Conversion Ratiomentioning

confidence: 81%

Productive performance of buffalo calves fed rations supplemented with folic acid

El-Sysy,

solaiman,

Boraei

et al. 2024

Al-Azhar Journal of Agricultural Research

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To investigate the impact of folic acid (FA) supplementation on growth performance and nutrient digestion in growing male buffalo calves, fifteen buffalo calves were randomly divided into three groups (five animals/group). The average initial live body weight of the buffalo calves was 181 ± 0.2 kg. Three nutritional groups of calves were randomly assigned to receive one of the three experimental rations; the control group (T1) was fed the basal diet; the second group (T2) was fed the control ration plus 50 mg of folic acid per head /day, and the third group (T3) was fed the control ration plus 75 mg of folic acid per head /day. Daily gain recorded by T2 was (0.77 kg/h/d) somewhat higher than T1 (0.75 kg/h/d) followed by T3 (0.85 kg/h/d). The daily gain of calves that received rations of folic acid 75 mg/h/day was slightly higher than that of calves that received rations without folic acid supplementation (control group). The total dry matter intake and feed conversion ratio were not significantly affected by folic acid administration. The digestibility coefficients for DM, OM, CP and CF of T3 were significantly greater than those of T1 (control group), but there was no statistically significant difference between T1 and T2 or T2 and T3. The third treatment recorded highest value for protein digestibility coefficients, while the first treatment recorded lowest value, and the differences were statistically non-significant. The supplementation of FA to buffalo calves' rations significantly improved the amount of total digestible nutrients and digestible crude protein.

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“…The findings of another study (10) that choline supplementation in rations did not change NEFA and BHBA levels in comparison to control groups were in agreement with those obtained in this study. Evans et al (23) reported that choline addition to the rations of dairy cattle in the transition period may help reduce NEFA levels in the blood. In this study, there were numerical reductions in the serum NEFA levels in the groups for which RPC was added to the rations.…”

Section: Discussionmentioning

confidence: 99%

The effects of supplementation of rumen-protected choline on some blood and milk metabolites in the transition period of dairy cattle

Alan¹,

Salman²

2019

Turk J Vet Anim Sci

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The aim of this study was to investigate nonesterified fatty acid (NEFA), beta-hydroxy butyric acid (BHBA), and milk urea nitrogen (MUN) profiles for dairy cows fed with rumen-protected choline (RPC) during the transition period. A total of 30 dairy cows were allocated to one control and two experimental groups (10 animals per group) and were fed from 3 weeks before calving to 21 days in milk. The control was fed only the basal diet. Treatment groups 1 and 2 were fed a basal diet containing 60 and 120 g/head/day RPC, respectively. The differences between groups were insignificant for MUN levels of colostrum and milk. There were no significant differences (P > 0.05) between the groups in terms of serum NEFA or BHBA levels. RPC supplementation did not have a significant effect on energy or protein metabolism of dairy cows during the transition period. The main effects of the periods without group effects in the model were highly significant (P < 0.01) for NEFA and BHBA. There is no need to add RPC to rations formulated as isocaloric and isonitrogenic for optimal rumen fermentation in dairy cows during the transition period. To better understand the effect of RPC on dairy cows during the transition period, there is a need for further studies of animals with known metabolic profiles, and those having high milk yields or metabolic disorders.

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Effects of a Protected Vitamin and Choline Supplement in the Transition Period on Dairy Cow Metabolic Parameters and Health

Cited by 4 publications

References 19 publications

Effect of rumen-protected B vitamins and choline supplementation on health, production, and reproduction in transition dairy cows

Effect of rumen-protected B vitamins and choline supplementation on health, production, and reproduction in transition dairy cows

Productive performance of buffalo calves fed rations supplemented with folic acid

The effects of supplementation of rumen-protected choline on some blood and milk metabolites in the transition period of dairy cattle

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