Effects of a soy protein product on serum and tissue cholesterol concentratins in swine fed high-fat, high-cholesterol diets

Effect of soybean protein on coprostanol production and cholesterol metabolism in cholesterol-fed rats.

“…Key Words cholesterol, coprostanol, soybean protein Soybean protein has been recently noticed for its hypocholesterolaemic effect (1)(2)(3)(4)(5). We also reported that when a diet was used containing 0.5% of cholesterol, the concentrations of plasma and liver cholesterol were lower in rats fed soybean protein than in those fed casein and HDL-cholesterol levels were higher in the soybean protein group (6).…”

Metabolism of cholesterol and triglycerides in young pigs fed beef-based, soy-based, or conventional diets

“…Their work is based on the traditional concepts of cholesterol balance (Kim et al, 1974(Kim et al, , 1975(Kim et al, , 1983. In summary, their experiments with pigs have shown: (1) no differences in fecal excretion of neutral or acidic steroids in pigs fed either soy or casein diets in the 1978 study, but greater excretion of both types of steroids in soy protein-fed pigs in the 1980 study; (2) no differences in dietary cholesterol absorption resul ting from type of dietary protein (Kim et al, 1978); (3) no differences in whole body cholesterol synthesis (Kim et al, 1978) or hepatic HMG-CoA reductase activities (Kim et al, 1980) caused by type of dietary protein; and (4) greater cholesterol content of the whole body of pigs fed casein than of those fed soy protein (Kim et al, 1978).…”

“…Studies with young male Yorkshire pigs (Kim et al, 1978;Kim et al, 1980) (Kim et al, 1978). Kim et al (1983) also found that amount of protein in the diet affected serum cholesterol concentra tions.…”

“…The effects cf supplementation of casein and soy protein diets with glycine or methionine also were examined (Kim et al , 1978). Methionine supplementation of either diet and glycine supplementation of the soy diet had no effect on serum cholesterol.…”

Efeito do consumo de tremoço (Lupinus albus) e seu isolado protéico no metabolismo do colesterol em hamsters hipercolesterolemizados

“…A maioria dos estudos que testaram o efeito hipocolesterolêmico do consumo de leguminosas comprovou tal aptidão, mesmo quando as dietas à base de leguminosas ou seus componentes eram comparadas com dietas isoprotéicas e isoenergéticas (ANDERSON et al, 1984;KINGMAN et al, 1993;MAJOR, 2002). Diversos componentes são apontados como os responsáveis pelo efeito hipocolesterolêmico desses alimentos, como as suas frações protéicas e respectivos perfis de aminoácidos (KIM et al, 1978;KRITCHEVSKY, 1979), as frações lipídicas e as fibras (SHUTLER et al, 1987), as saponinas (OAKENFULL;FENWICK, 1978;SIDHU et al, 1987) e os fitoesteróis (CARR et al, 2002). No entanto, os mecanismos subjacentes a este efeito ainda são pouco conhecidos e inconclusivos.…”