“…Stand-alone interventions comprised 13 studies, 223,233,235,236,239,246,248,249,251,252,[254][255][256] but in 19 studies 224,227,229-234, 237,238,240-245,247,250,253 the digital communication tool was included within a wider intervention such as a web-based therapy or web-based system (portal, telemedicine, telehealth, etc. ), which allowed a two-way communication (e-mails, web messaging, videoconferencing, etc.)…”