Effects of a therapeutic lifestyle change diet and supplementation with Q10 plus L-carnitine on quality of life in patients with myocardial infarction: A randomized clinical trial

Sharifi, Mohammad Hossein; Eftekhari, Mohammad Hassan; Ostovan, Mohammad Ali; Rezaianazadeh, Abbas

doi:10.15171/jcvtr.2017.03

Cited by 19 publications

(21 citation statements)

References 31 publications

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“…It has been estimated that men with metabolic syndrome have 2–3 times greater probability for cardiovascular disease (CVD) than those without metabolic syndrome [ 2 – 4 ]. Overall, metabolic syndrome is associated with a twofold increase in the risk of CVD, CVD mortality, and stroke, and a 1.5-fold increase in risk of all-cause mortality [ 5 – 7 ]. In fact, coronary artery disease (CAD) is among the main causes of death in developed countries, while it has a growing epidemic in developing countries [ 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

Framingham risk score for estimation of 10-years of cardiovascular diseases risk in patients with metabolic syndrome

Jahangiry

Farhangi

Rezaei

2017

J Health Popul Nutr

125

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BackgroundThere are a few studies evaluating the predictive value of Framingham risk score (FRS) for cardiovascular disease (CVD) risk assessment in patients with metabolic syndrome in Iran. Because of the emerging high prevalence of CVD among Iranian population, it is important to predict its risk among populations with potential predictive tools. Therefore, the aim of the current study is to evaluate the FRS and its determinants in patients with metabolic syndrome.MethodsIn the current cross-sectional study, 160 patients with metabolic syndrome diagnosed according to the National Cholesterol Education Adult Treatment Panel (ATP) III criteria were enrolled. The FRS was calculated using a computer program by a previously suggested algorithm.ResultsTotally, 77.5, 16.3, and 6.3% of patients with metabolic syndrome were at low, intermediate, and high risk of CVD according to FRS categorization. The highest prevalence of all of metabolic syndrome components were in low CVD risk according to the FRS grouping (P < 0.05), while the lowest prevalence of these components was in high CVD risk group (P < 0.05). According to multiple logistic regression analysis, high systolic blood pressure (SBP) and fasting serum glucose (FSG) were potent determinants of intermediate and high risk CVD risk of FRS scoring compared with low risk group (P < 0.05).ConclusionIn the current study, significant associations between components of metabolic syndrome and different FRS categorization among patients with metabolic syndrome were identified. High SBP and FSG were associated with meaningfully increased risk of CVD compared with other parameters.Trial registrationsThe study is not a trial; the registration number is not applicable.

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Section: Introductionmentioning

confidence: 99%

Framingham risk score for estimation of 10-years of cardiovascular diseases risk in patients with metabolic syndrome

Jahangiry

Farhangi

Rezaei

2017

J Health Popul Nutr

125

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“…16 In another study, Sharifi et al showed that both a therapeutic lifestyle-change diet and supplementation with CoQ 10 (150 mg/day) and L-carnitine had a positive effect on the physical and emotional subscales of the MacNew questionnaire in patients with myocardial infarction. 17 In addition, Morris et al illustrated the CoQ 10 's potential role in improving QOL in patients with Parkinson's disease and fibromyalgia. Also, it showed antidepressive effects and significantly reduced fatigue and improved ergonomic performance during exercise.…”

Section: Discussionmentioning

confidence: 99%

“…15 Studies on the effectiveness of CoQ 10 on QOL in different diseases have indicated that this supplement can have a beneficial effect on QOL. [16][17][18] However, there have been few studies on breast cancer, 9 and to our knowledge, a trial evaluating the effect of CoQ 10 alone in breast cancer patients has not been done yet. Considering the high prevalence of breast cancer, in addition to its importance and effects on all life dimensions of patients, focusing on QOL as it relates to health and finding solutions to ameliorate QOL of these patients seems necessary.…”

Section: Introductionmentioning

confidence: 99%

<p>The Effect of CoQ10 Supplementation on Quality of Life in Women with Breast Cancer Undergoing Tamoxifen Therapy: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial</p>

Hosseini¹,

Zahrooni²,

Ahmadzadeh³

et al. 2020

PRBM

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Background: Survival rates among breast cancer patients and the number of patients living with treatment side effects have improved, leading to increased focus on quality of life (QOL). The objective of this study was to determine the efficacy of CoQ 10 on QOL scores among breast cancer patients in Iranian undergoing tamoxifen therapy. Methods: Thirty breast cancer patients were randomized into two groups. The first group received 100 mg CoQ 10 , and the second group took fplacebo once a day for 8 weeks. QOL was evaluated by a standard QOL questionnaire and a specific questionnaire on QOL of breast cancer patients at baseline and the end of the study. Also, physical activity of patients was assessed with the IPAQ questionnaire and dietary intake determined by a 3-day dietary record. Results: The data of 30 subjects were analyzed. According to QOL C30 data, CoQ 10 led to a significant increase in physical functioning (P=0.029), emotional functioning (P=0.031), and cognitive functioning (P=0.023) compared to placebo. Symptom scales revealed a notable reduction in appetite loss in the first group (P=0.01). Global health status showed no significant changes in either study arm. On the QOL BR23, progress in functions and decline in symptoms were not statistically significant. Arm symptoms showed significant reduction (P=0.022) in patients that received placebo. Conclusion: This trial indicates that CoQ 10 supplementation has effects in ameliorating some dimensions of QOL in breast cancer patients. To generalize the results, larger and longer intervention studies are needed. Clinical Trial Registration: IRCT2015042021874N1.

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“…Behavioural changes following an MI are critical for addressing the risk of future morbidity and mortality (Gaalema, Elliott, Morford, Higgins, & Ades, ). Adherence to secondary prevention guidelines that include the modification of lifestyle behaviours such as quitting smoking, improving diet and increasing moderate physical activity can significantly reduce the risk of recurrent events or deaths after MI (Sharifi, Eftekhari, Ostovan, & Rezaianazadeh, ; Wallert, Madison, Held, & Olsson, ).…”

Section: Introductionmentioning

confidence: 99%

The dissimilarity between myocardial infarction patients’ and spouses’ illness perception and its relation to patients’ lifestyle

Qin

Chen

Suo

et al. 2020

Journal of Clinical Nursing

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Aim and objectives To examine the dissimilarity between Chinese myocardial infarction (MI) patients’ and spouses’ illness perceptions (IPs), and to explore the relationship between patients’ IP, differences in couples’ IP and patients’ lifestyle after discharge. Background An individual's IP is affected and moderated by several factors, including the social context. One of the most influential members of the social network of patients is the spouse. Design Cross‐sectional design. Methods From April 2016–April 2017, 111 MI patients and their spouses were recruited. Before discharge from hospital, revised Illness Perception Questionnaire was administered to MI patients and their spouses separately. Two months after discharge, patients’ lifestyle was assessed using Health Promoting Lifestyle Profile II. The manuscript was organised according to STROBE guidelines. Results Spouses were more likely to believe that the illness would last for a long time, and patients perceived MI as being more controllable than their spouses did. The patient–spouse dissimilarity in the perception of consequences was negatively correlated with both nutrition and stress control behaviours. Patients in couples with more dissimilar perception of environmental factors as a cause were more likely to choose a healthy diet, while patients in couples with more dissimilar perceived treatment control were more able to control stress. Conclusion There are both similarities and dissimilarities between MI patients’ and spouses’ IP, and these dissimilarities contributed the majority of the explained variance in patients’ lifestyle after discharge. Relevance to clinical practice We should consider both couples when examining how a patient copes with a chronic illness.

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Effects of a therapeutic lifestyle change diet and supplementation with Q10 plus L-carnitine on quality of life in patients with myocardial infarction: A randomized clinical trial

Cited by 19 publications

References 31 publications

Framingham risk score for estimation of 10-years of cardiovascular diseases risk in patients with metabolic syndrome

Framingham risk score for estimation of 10-years of cardiovascular diseases risk in patients with metabolic syndrome

<p>The Effect of CoQ10 Supplementation on Quality of Life in Women with Breast Cancer Undergoing Tamoxifen Therapy: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial</p>

The dissimilarity between myocardial infarction patients’ and spouses’ illness perception and its relation to patients’ lifestyle

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