“…Whereas previous studies often assessed one specific pre-ICU health outcome, for example, cognitive functioning ( 13 , 27 ) or quality of life ( 28 , 29 ), we assessed patient’s physical, mental, and cognitive functioning, as well as the quality of life, thereby providing a more complete picture of the pre-ICU health status. However, rates of pre-ICU frailty, anxiety, depression, and cognitive impairment are lower compared with other studies ( 13 , 17 , 27 , 40 , 41 ). This may be explained by differences in inclusion criteria: in other studies, only elderly patients ( 13 , 27 ) or medical patients with an ICU LOS of more than 48 hours ( 41 ) were included.…”