Effects of acetabular resurfacing component material and fixation on the strain distribution in the pelvis

Thompson, Mark S.; Northmore-Ball,; Tanner, K. E.

doi:10.1243/09544110260138727

Cited by 44 publications

(36 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is therefore evident from the study that implantation causes localised increases in strains in a few locations around the acetabulum. These changes in load transfer mechanism after implantation are corroborated by published data [43][44][45][46]. In the clinical study by Wright et al [43], periacetabular bone-mineral density was assessed in a group of twenty-six patients who underwent primary total hip arthroplasty using press-fit acetabular cups.…”

Section: Discussionsupporting

confidence: 54%

Experimental validation of numerically predicted strain and micromotion in intact and implanted composite hemi-pelvises

Ghosh

Gupta

Dickinson

et al. 2012

Proc Inst Mech Eng H

View full text Add to dashboard Cite

The failure mechanisms of acetabular prostheses may be investigated by understanding the changes in load transfer due to implantation, and analysis of the implant-bone micromotion. Computational finite element (FE) models allow detailed mechanical analysis of the implant-bone structure, but their validity must be assessed as part of a verification process before they can be employed in pre-clinical investigations. To this end, in the present study, FE models of composite hemi-pelvises, intact and implanted with an acetabular cup, were experimentally verified. Strains and implant-bone micromotions in the hemi-pelvises were compared with those predicted by the equivalent FE models. Regression analysis indicated close agreement between the measured and FE strains, with a high correlation coefficient (0.95-0.98), a low standard error of the estimate (36-53µε) and a low error in regression slope (7-11%). Measured micromotions along three orthogonal directions were small, less than 30µm, whereas the FE predicted values were found to be less than 85µm. Although the trends were similar, the observed deviations may be due to estimation of the interfacial press-fit used in the FE model, and additional artefacts in experimental micromotion measurement which are avoided in the FE model. This supports the FE model as a valid predictor of the experimentally measured strain in the composite pelvis models, confirming its suitability for further computational investigations on acetabular prostheses. 4 IntroductionLoosening of the acetabular prosthesis is responsible for the majority of failures in total hip replacement [1][2][3][4]. However, biomechanical investigations into phenomena such as the load transfer mechanism across the pelvis and the acetabular reconstruction remain relatively under-investigated as compared to the femoral component. Measurement of such phenomena across the intact and implanted bones would be a useful step forward in the analysis of acetabular failure, and to date this has commonly been evaluated using finite element (FE) analysis [5][6][7][8][9][10][11]. The validity of the FE model generation process should be assessed using quantitative comparisons between computational predictions and experimental results [Anderson et al., 2007].Researchers have investigated the strain/stress distributions in the intact pelvis by comparing experimentally measured strains with those predicted by the equivalent FE model [5,7,10]. However, all these studies featured large areas of rigid fixation, which may not be fully representative of in-vivo bone support. Moreover, there is a scarcity of experimental data on strain measurement in intact and implanted pelvises which could be used to identify potential links between changes in strain distribution due to implantation and clinical failure mechanisms [12][13][14].The initial fixation of an uncemented implant is dependent on the primary stability, which is usually indicated by the amount of micromotion at the implant-bone interface, prior to bone-ingrowth, induc...

show abstract

Section: Discussionsupporting

confidence: 54%

Experimental validation of numerically predicted strain and micromotion in intact and implanted composite hemi-pelvises

Ghosh

Gupta

Dickinson

et al. 2012

Proc Inst Mech Eng H

View full text Add to dashboard Cite

show abstract

“…Recent developments in advanced polymer composite technology have produced bearing materials with low long-term wear and closer stiffness (E) to bone tissue (EE17 GPa) than metals (EE200 GPa), ceramics (EE350 GPa) or polymers (EE0.9 GPa). Accordingly, these materials are predicted to promote less adverse bone adaptation, a theory which has been supported by computer simulations (Huiskes et al, 1992;Thompson et al, 2002;Manley et al, 2006).…”

Section: Introductionmentioning

confidence: 87%

The influence of acetabular cup material on pelvis cortex surface strains, measured using digital image correlation

Dickinson¹,

Taylor²,

Browne³

2012

Journal of Biomechanics

View full text Add to dashboard Cite

Replacement 32All authors have made a substantial contribution to this work, have read and concur with 33 the content of the manuscript. 34 This work has not been submitted for publication elsewhere, but was presented as a poster 35 at the ISTA conference 2011. The CFR-PEEK cup was observed to produce the closest bone strain to the intact hip in the main 50 load path, the superior peri-acetabular cortex (+12% on average, R 2 =0.84), in comparison to CoCr 51 (+40%, R 2 =0.91) and UHWMPE cups (-26%, R 2 =0.94). Clinical observations have indicated that 52 increased periacetabular cortex loading may result in reduced polar cancellous bone loading, leading 53 to longer term losses in periprosthetic bone mineral density. This study provides experimental 54 evidence to verify previous computational studies, indicating that cups produced using materials 55 with stiffness closer to cortical bone recreate physiological cortical bone strains more closely and 56 could, therefore, potentially promote less adverse bone adaptation than stiffer press-fitted implants 57 in current use. 58 59 60 4

show abstract

“…A linear calibration of CT grey value and apparent density and power law relationship between apparent density and Young's modulus were used for the purpose (Dalstra and Huiskes 1995;Anderson et al 2005;Zhang et al 2010;Ghosh et al 2013bGhosh et al , 2015Ghosh and Gupta 2014). The cortical bone was assumed to be homogenous with Young's modulus of 17 GPa (Dalstra and Huiskes 1995;Anderson et al 2005;Thompson et al 2002;Ghosh et al 2013bGhosh et al , 2015Ghosh and Gupta 2014). The Poisson's ratios of the cancellous and cortical bones were taken as 0.2 and 0.3, respectively (Anderson et al 2005;Zhang et al 2010;Ghosh et al 2013bGhosh et al , 2015Ghosh and Gupta 2014).…”

Section: Development Of Fe Model Of An Implanted Pelvismentioning

confidence: 99%

“…The muscle forces were applied as distributed loads on the patched areas identified as muscle attachment sites on the pelvis (Ghosh et al 2013b(Ghosh et al , 2015. Displacements in all directions were restrained at the pubic symphysis and sacroiliac joint (Thompson et al 2002;Dalstra and Huiskes 1995;Clarke et al 2013;Ghosh et al 2013bGhosh et al , 2015.…”

Section: Applied Loading Conditionsmentioning

confidence: 99%

“…In order to simulate the mechanical environment within the microscale model, a mapping framework needs to be developed that would link the physiological boundary conditions and host bone material properties of the macroscale model to the microscale model. Earlier FE studies on macroscale implanted pelvis either analysed immediate post-operative condition (Spears et al 2001; Thompson et al 2002;Janssen et al 2010;Zhang et al 2010;Besong et al 2001;Widmer et al 2002;Udofia et al 2004;Ong et al 2006) or periacetabular bone adaptation (Levenston et al 1993;Manley et al 2006;Ghosh et al 2013b;Ghosh and Gupta 2014). However, none of these studies has numerically investigated peri-acetabular bone ingrowth.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Bone ingrowth around porous-coated acetabular implant: a three-dimensional finite element study using mechanoregulatory algorithm

Mukherjee

Gupta

2015

Biomech Model Mechanobiol

View full text Add to dashboard Cite

Fixation of uncemented implant is influenced by peri-prosthetic bone ingrowth, which is dependent on the mechanical environment of the implant-bone structure. The objective of the study is to gain an insight into the tissue differentiation around an acetabular component. A mapping framework has been developed to simulate appropriate mechanical environment in the three-dimensional microscale model, implement the mechanoregulatory tissue differentiation algorithm and subsequently assess spatial distribution of bone ingrowth around an acetabular component, quantitatively. The FE model of implanted pelvis subjected to eight static load cases during a normal walking cycle was first solved. Thereafter, a mapping algorithm has been employed to include the variations in implant-bone relative displacement and host bone material properties from the macroscale FE model of implanted pelvis to the microscale FE model of the beaded implant-bone interface. The evolutionary tissue differentiation was observed in each of the 13 microscale models corresponding to 13 acetabular regions. The total implant-bone relative displacements, averaged over each region of the acetabulum, were found to vary between 10 and 60 μm. Both the linear elastic and biphasic poroelastic models predicted similar mechanoregulatory peri-prosthetic tissue differentiation. Considerable variations in bone ingrowth (13-88%), interdigitation depth (0.2-0.82 mm) and average tissue Young's modulus (970-3430 MPa) were predicted around the acetabular cup. A progressive increase in the average Young's modulus, interdigitation depth and decrease in average radial strains of newly formed tissue layer were also observed. This scheme can be extended to investigate tissue differentiation for different surface texture designs on the implants.

show abstract

Effects of acetabular resurfacing component material and fixation on the strain distribution in the pelvis

Cited by 44 publications

References 24 publications

Experimental validation of numerically predicted strain and micromotion in intact and implanted composite hemi-pelvises

Experimental validation of numerically predicted strain and micromotion in intact and implanted composite hemi-pelvises

The influence of acetabular cup material on pelvis cortex surface strains, measured using digital image correlation

Bone ingrowth around porous-coated acetabular implant: a three-dimensional finite element study using mechanoregulatory algorithm

Contact Info

Product

Resources

About